Poly(ADP-ribose) polymerase family member 16 (Q21125793)

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mammalian protein found in Homo sapiens

protein mono-ADP-ribosyltransferase PARP16
poly [ADP-ribose] polymerase 16
ADP-ribosyltransferase diphtheria toxin-like 15
mono [ADP-ribose] polymerase PARP16
PARP16
PARP-16

Language	Label	Description	Also known as
English	Poly(ADP-ribose) polymerase family member 16	mammalian protein found in Homo sapiens	protein mono-ADP-ribosyltransferase PARP16 poly [ADP-ribose] polymerase 16 ADP-ribosyltransferase diphtheria toxin-like 15 mono [ADP-ribose] polymerase PARP16 PARP16 PARP-16

Statements

1 reference

13 November 2019

UniProt protein ID

Poly(ADP-ribose) polymerase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

transferase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

determination method or standard

1 reference

26 September 2017

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

protein serine/threonine kinase activator activity

determination method or standard

1 reference

26 September 2017

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

protein binding

determination method or standard

glycosyltransferase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

NAD+ ADP-ribosyltransferase activity

determination method or standard

5 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

26 September 2017

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

26 September 2017

PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

26 September 2017

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

NAD+ ADP-ribosyltransferase activity

determination method or standard

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

1 January 2018

PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

1 January 2018

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

determination method or standard

protein serine/threonine kinase activator activity

determination method or standard

protein ADP-ribosylase activity

determination method or standard

1 reference

8 April 2019

Family-wide analysis of poly(ADP-ribose) polymerase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

NAD+ ADP-ribosyltransferase activity

determination method or standard

4 references

8 April 2019

PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

8 April 2019

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

integral component of membrane

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

nuclear envelope

determination method or standard

1 reference

26 September 2017

PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

endoplasmic reticulum membrane

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

endoplasmic reticulum tubular network

determination method or standard

1 reference

26 September 2017

PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

nuclear envelope

determination method or standard

endoplasmic reticulum

determination method or standard

3 references

8 April 2019

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

endoplasmic reticulum tubular network

determination method or standard

biological process

endoplasmic reticulum unfolded protein response

determination method or standard

1 reference

26 September 2017

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

protein auto-ADP-ribosylation

determination method or standard

2 references

26 September 2017

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

26 September 2017

PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

response to unfolded protein

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

protein ADP-ribosylation

determination method or standard

2 references

26 September 2017

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

26 September 2017

PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N5Y8&geneProductId=UniProtKB:Q8N5Y8

determination method or standard

negative regulation of cell death

determination method or standard

1 reference

8 April 2019

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

positive regulation of protein serine/threonine kinase activity

determination method or standard

1 reference

8 April 2019

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

NAD biosynthesis via nicotinamide riboside salvage pathway

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

cellular response to leukemia inhibitory factor

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

protein ADP-ribosylation

determination method or standard

3 references

8 April 2019

PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

8 April 2019

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

endoplasmic reticulum unfolded protein response

determination method or standard

IRE1-mediated unfolded protein response

determination method or standard

1 reference

8 April 2019

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

protein auto-ADP-ribosylation

determination method or standard

3 references

8 April 2019

PARP16/ARTD15 is a novel endoplasmic-reticulum-associated mono-ADP-ribosyltransferase that interacts with, and modifies karyopherin-ß1

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

8 April 2019

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

8 April 2019

Family-wide analysis of poly(ADP-ribose) polymerase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

protein mono-ADP-ribosylation

determination method or standard

1 reference

8 April 2019

Family-wide analysis of poly(ADP-ribose) polymerase activity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N5Y8

determination method or standard

poly(ADP-ribose) polymerase, catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8N5Y8

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000261888

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000261888

ENSP00000396118

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000396118

ENSP00000457982

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000457982

ENSP00000496935

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000496935

PDB structure ID

1 reference

UniProt protein ID

20 March 2016

language of work or name

Sitelinks

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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