General transcription factor IIH subunit 5 (Q21122186)

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mammalian protein found in Homo sapiens

• general transcription factor IIH subunit 5
• GTF2H5
• general transcription factor IIH, polypeptide 5
• TFB5 ortholog
• TFIIH basal transcription factor complex TTD-A subunit
• General transcription factor IIH polypeptide 5
• TFIIH basal transcription factor complex TTDA subunit

edit

Language	Label	Description	Also known as
English	General transcription factor IIH subunit 5	mammalian protein found in Homo sapiens	general transcription factor IIH subunit 5 GTF2H5 general transcription factor IIH, polypeptide 5 TFB5 ortholog TFIIH basal transcription factor complex TTD-A subunit General transcription factor IIH polypeptide 5 TFIIH basal transcription factor complex TTDA subunit

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q6ZYL4

part of

TFB5-like superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q6ZYL4

TFIIH subunit TTDA/Tfb5

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q6ZYL4

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q6ZYL4

encoded by

GTF2H5

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q6ZYL4

molecular function

rDNA binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

protein binding

determination method

IPI

3 references

retrieved

8 April 2019

stated in

Structural basis for group A trichothiodystrophy

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IPI

retrieved

8 April 2019

stated in

Dynamic interaction of TTDA with TFIIH is stabilized by nucleotide excision repair in living cells

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IPI

retrieved

8 April 2019

stated in

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IPI

cell component

nucleoplasm

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

nucleolus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

transcription factor TFIIH core complex

determination method

IEA

1 reference

retrieved

7 November 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZYL4&geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

nucleus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q6ZYL4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

transcription factor TFIID complex

determination method

IDA

1 reference

retrieved

7 November 2018

stated in

Near-atomic resolution visualization of human transcription promoter opening

GOA

curator

UniProt

UniProt protein ID

Q6ZYL4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZYL4&geneProductId=UniProtKB:Q6ZYL4

determination method

IDA

transcription factor TFIIH core complex

determination method

IBA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IBA

transcription factor TFIID complex

determination method

IBA

IDA

2 references

retrieved

8 April 2019

stated in

Near-atomic resolution visualization of human transcription promoter opening

GOA

curator

UniProt

UniProt protein ID

Q6ZYL4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IBA

transcription factor TFIIH holo complex

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IBA

biological process

termination of RNA polymerase I transcription

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

regulation of transcription, DNA-templated

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

transcription initiation from RNA polymerase I promoter

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

transcription elongation from RNA polymerase II promoter

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

7-methylguanosine mRNA capping

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

transcription by RNA polymerase II

determination method

TAS

1 reference

retrieved

7 November 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZYL4&geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

transcription, DNA-templated

determination method

IEA

1 reference

retrieved

24 April 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q6ZYL4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZYL4&geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

cellular response to DNA damage stimulus

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q6ZYL4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

global genome nucleotide-excision repair

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

cellular response to gamma radiation

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

rRNA processing

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

transcription-coupled nucleotide-excision repair

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

transcription initiation from RNA polymerase II promoter

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

nucleotide-excision repair, DNA incision

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

nucleotide-excision repair, preincision complex assembly

determination method

IEA

TAS

2 references

retrieved

7 November 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZYL4&geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

retrieved

7 November 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZYL4&geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

nucleotide-excision repair

determination method

IEA

IMP

3 references

retrieved

7 November 2018

stated in

Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethality

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZYL4&geneProductId=UniProtKB:Q6ZYL4

determination method

IMP

retrieved

7 November 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZYL4&geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

retrieved

7 November 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZYL4&geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

nucleotide-excision repair, DNA incision, 5'-to lesion

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

DNA repair

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q6ZYL4

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

nucleotide-excision repair, preincision complex stabilization

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

transcription elongation from RNA polymerase I promoter

determination method

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6ZYL4&geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

nucleotide-excision repair

determination method

IBA

IEA

IMP

4 references

retrieved

8 April 2019

stated in

Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethality

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IMP

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IBA

nucleotide-excision repair, preincision complex assembly

determination method

IBA

IEA

TAS

3 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IBA

transcription by RNA polymerase II

determination method

IBA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IBA

phosphorylation of RNA polymerase II C-terminal domain

determination method

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IBA

nucleotide-excision repair, DNA duplex unwinding

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

nucleotide-excision repair, DNA incision, 3'-to lesion

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

transcription elongation from RNA polymerase I promoter

determination method

IEA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6ZYL4

determination method

IEA

Identifiers

RefSeq protein ID

NP_997001

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

404672

XP_016866351

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

404672

UniProt protein ID

Q6ZYL4

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q6ZYL4

Ensembl protein ID

ENSP00000476100

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000476100

ENSP00000497338

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000497338

PDB structure ID

1YDL

1 reference

stated in

UniProt

UniProt protein ID

Q6ZYL4

retrieved

4 August 2016

language of work or name

English

2JNJ

1 reference

stated in

UniProt

UniProt protein ID

Q6ZYL4

retrieved

4 August 2016

language of work or name

English

5IY8

1 reference

stated in

UniProt

UniProt protein ID

Q6ZYL4

retrieved

4 August 2016

language of work or name

English

5IY6

1 reference

stated in

UniProt

UniProt protein ID

Q6ZYL4

retrieved

4 August 2016

language of work or name

English

5IY7

1 reference

stated in

UniProt

UniProt protein ID

Q6ZYL4

retrieved

4 August 2016

language of work or name

English

5IVW

1 reference

stated in

UniProt

UniProt protein ID

Q6ZYL4

retrieved

4 August 2016

language of work or name

English

5IY9

1 reference

stated in

UniProt

UniProt protein ID

Q6ZYL4

retrieved

4 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21122186&oldid=2022993205"