Peptidyl arginine deiminase 4 (Q21123689)

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mammalian protein found in Homo sapiens

• Peptidylarginine deiminase IV
• HL-60 PAD
• protein-arginine deiminase type IV
• PADI4
• PADI-H protein
• peptidyl arginine deiminase, type V
• peptidyl arginine deiminase, type IV
• protein-arginine deiminase type-4

edit

Language	Label	Description	Also known as
English	Peptidyl arginine deiminase 4	mammalian protein found in Homo sapiens	Peptidylarginine deiminase IV HL-60 PAD protein-arginine deiminase type IV PADI4 PADI-H protein peptidyl arginine deiminase, type V peptidyl arginine deiminase, type IV protein-arginine deiminase type-4

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UM07

part of

Protein-arginine deiminase, central domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UM07

Protein-arginine deiminase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UM07

Cupredoxin

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UM07

PAD, N-terminal domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UM07

Protein-arginine deiminase (PAD), central domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-arginine deiminase (PAD) N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-arginine deiminase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UM07

encoded by

PADI4

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UM07

molecular function

metal ion binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

arginine deiminase activity

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Discovery of peptidylarginine deiminase-4 substrates by protein array: antagonistic citrullination and methylation of human ribosomal protein S2

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IDA

protein binding

determination method or standard

IPI

2 references

retrieved

8 April 2019

stated in

Discovery of peptidylarginine deiminase-4 substrates by protein array: antagonistic citrullination and methylation of human ribosomal protein S2

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IPI

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IPI

hydrolase activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

protein-arginine deiminase activity

determination method or standard

IDA

IEA

IMP

TAS

8 references

retrieved

27 February 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

TAS

retrieved

27 February 2018

stated in

Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3)

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

TAS

retrieved

27 February 2018

stated in

Structural basis for Ca(2+)-induced activation of human PAD4

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

IMP

retrieved

27 February 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

27 February 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

27 February 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

27 February 2018

stated in

Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

IDA

retrieved

27 February 2018

stated in

Histone deimination antagonizes arginine methylation

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

IDA

calcium ion binding

determination method or standard

IDA

IEA

IMP

3 references

retrieved

8 April 2019

stated in

Structural basis for Ca(2+)-induced activation of human PAD4

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IMP

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

8 April 2019

stated in

Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IDA

arginine binding

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Structural basis for Ca(2+)-induced activation of human PAD4

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IMP

protein homodimerization activity

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Structural basis for Ca(2+)-induced activation of human PAD4

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IMP

protein-arginine deiminase activity

determination method or standard

IBA

IDA

IEA

IMP

TAS

8 references

retrieved

8 April 2019

stated in

Molecular characterization of peptidylarginine deiminase in HL-60 cells induced by retinoic acid and 1alpha,25-dihydroxyvitamin D(3)

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

TAS

retrieved

8 April 2019

stated in

Structural basis for Ca(2+)-induced activation of human PAD4

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IMP

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

8 April 2019

stated in

Histone deimination antagonizes arginine methylation

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IDA

retrieved

8 April 2019

stated in

Structural basis for histone N-terminal recognition by human peptidylarginine deiminase 4

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IBA

cell component

nucleoplasm

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

TAS

nucleus

determination method or standard

IDA

IEA

2 references

retrieved

27 February 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

27 February 2018

stated in

Histone deimination antagonizes arginine methylation

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

IDA

cytosol

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

TAS

cytoplasm

determination method or standard

IBA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IBA

protein-containing complex

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Structural basis for Ca(2+)-induced activation of human PAD4

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IMP

nucleus

determination method or standard

IBA

IDA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

8 April 2019

stated in

Histone deimination antagonizes arginine methylation

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IBA

biological process

chromatin remodeling

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

nucleosome assembly

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

regulation of transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

27 February 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

immune system process

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

27 February 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UM07&geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

stem cell population maintenance

determination method or standard

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

innate immune response

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

chromatin organization

determination method or standard

IEA

ISS

TAS

4 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9UM07

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IEA

arginine deiminase pathway

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Structural basis for Ca(2+)-induced activation of human PAD4

GOA

curator

Critical Assessment of Protein Function Annotation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UM07

determination method or standard

IMP

EC enzyme number

3.5.3.15

0 references

has part(s)

Protein-arginine deiminase (PAD), central domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UM07

Protein-arginine deiminase, C-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UM07

Protein-arginine deiminase (PAD) N-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UM07

Identifiers

MeSH descriptor ID

D000080002

subject named as

Protein-Arginine Deiminase Type 4

0 references

MeSH tree code

D08.811.277.721.500

0 references

RefSeq protein ID

NP_036519

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23569

XP_011539452

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23569

XP_011539453

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23569

XP_011539454

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23569

XP_011539455

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23569

XP_011539456

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23569

XP_011539457

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23569

XP_011539458

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23569

XP_011539459

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

23569

UniProt protein ID

Q9UM07

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9UM07

Ensembl protein ID

ENSP00000364597

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000364597

ENSP00000487021

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000487021

ENSP00000364602

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000364602

ENSP00000486726

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000486726

PDB structure ID

1WD8

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

1WD9

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

1WDA

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

2DEW

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

2DEX

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

2DEY

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

2DW5

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

3APM

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

3APN

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

3B1T

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

3B1U

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

4DKT

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

4X8C

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

4X8G

1 reference

stated in

UniProt

UniProt protein ID

Q9UM07

retrieved

9 August 2016

language of work or name

English

UMLS CUI

C0765808

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

25 May 2023

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21123689&oldid=2022999974"