Rho GTPase activating protein 6 (Q21135388)

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mammalian protein found in Homo sapiens

• ARHGAP6
• rho-type GTPase-activating protein 6
• Rho-type GTPase-activating protein RhoGAPX-1
• rho GTPase-activating protein 6

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Language	Label	Description	Also known as
English	Rho GTPase activating protein 6	mammalian protein found in Homo sapiens	ARHGAP6 rho-type GTPase-activating protein 6 Rho-type GTPase-activating protein RhoGAPX-1 rho GTPase-activating protein 6

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O43182

part of

Rho GTPase activation protein

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O43182

Rho GTPase-activating protein 6

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O43182

Rho GTPase-activating protein domain family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O43182

encoded by

ARHGAP6

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O43182

molecular function

phospholipase binding

determination method or standard

IPI

1 reference

retrieved

27 March 2018

stated in

Regulation of phospholipase C-delta1 by ARGHAP6, a GTPase-activating protein for RhoA: possible role for enhanced activity of phospholipase C in hypertension

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43182&geneProductId=UniProtKB:O43182

determination method or standard

IPI

SH3 domain binding

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

phospholipase activator activity

determination method or standard

IDA

1 reference

retrieved

27 March 2018

stated in

Regulation of phospholipase C-delta1 by ARGHAP6, a GTPase-activating protein for RhoA: possible role for enhanced activity of phospholipase C in hypertension

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43182&geneProductId=UniProtKB:O43182

determination method or standard

IDA

GTPase activator activity

determination method or standard

IEA

TAS

4 references

retrieved

7 November 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43182&geneProductId=UniProtKB:O43182

determination method or standard

TAS

retrieved

7 November 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O43182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43182&geneProductId=UniProtKB:O43182

determination method or standard

IEA

retrieved

7 November 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43182&geneProductId=UniProtKB:O43182

determination method or standard

IEA

retrieved

7 November 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43182&geneProductId=UniProtKB:O43182

determination method or standard

IEA

GTPase activator activity

determination method or standard

IEA

3 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

phospholipase activator activity

determination method or standard

IBA

1 reference

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IBA

phospholipase binding

determination method or standard

IBA

1 reference

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IBA

cell component

cytoplasm

determination method or standard

IEA

IMP

2 references

retrieved

9 May 2019

stated in

Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IMP

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O43182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

cytosol

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

TAS

actin filament

determination method or standard

NAS

1 reference

retrieved

9 May 2019

stated in

Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA

GOA

curator

UniProt

UniProt protein ID

O43182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

NAS

actin cytoskeleton

determination method or standard

ISS

IEA

2 references

retrieved

9 May 2019

stated in

Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

ISS

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

biological process

actin filament organization

determination method or standard

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

regulation of GTPase activity

determination method or standard

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

activation of phospholipase C activity

determination method or standard

IDA

1 reference

retrieved

27 March 2018

stated in

Regulation of phospholipase C-delta1 by ARGHAP6, a GTPase-activating protein for RhoA: possible role for enhanced activity of phospholipase C in hypertension

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43182&geneProductId=UniProtKB:O43182

determination method or standard

IDA

positive regulation of phospholipase activity

determination method or standard

IDA

1 reference

retrieved

27 March 2018

stated in

Regulation of phospholipase C-delta1 by ARGHAP6, a GTPase-activating protein for RhoA: possible role for enhanced activity of phospholipase C in hypertension

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O43182&geneProductId=UniProtKB:O43182

determination method or standard

IDA

focal adhesion assembly

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

actin filament polymerization

determination method or standard

NAS

1 reference

retrieved

9 May 2019

stated in

Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA

GOA

curator

UniProt

UniProt protein ID

O43182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

NAS

positive regulation of GTPase activity

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

Rho protein signal transduction

determination method or standard

NAS

TAS

2 references

retrieved

9 May 2019

stated in

Cloning and characterization of a novel rho-type GTPase-activating protein gene (ARHGAP6) from the critical region for microphthalmia with linear skin defects

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

TAS

retrieved

9 May 2019

stated in

Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA

GOA

curator

UniProt

UniProt protein ID

O43182

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

NAS

negative regulation of stress fiber assembly

determination method or standard

IMP

1 reference

retrieved

9 May 2019

stated in

Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IMP

regulation of small GTPase mediated signal transduction

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

TAS

negative regulation of focal adhesion assembly

determination method or standard

IMP

1 reference

retrieved

9 May 2019

stated in

Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IMP

signal transduction

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

positive regulation of signal transduction

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IEA

activation of phospholipase C activity

determination method or standard

IBA

1 reference

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O43182

determination method or standard

IBA

has part(s)

Rho GTPase-activating protein domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O43182

Identifiers

RefSeq protein ID

NP_001274171

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

395

NP_006116

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

395

NP_038267

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

395

NP_038286

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

395

UniProt protein ID

O43182

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O43182

Ensembl protein ID

ENSP00000302312

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000302312

ENSP00000338967

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000338967

ENSP00000370094

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000370094

ENSP00000370112

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000370112

ENSP00000435767

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000435767

ENSP00000370093

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000370093

ENSP00000499351

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000499351

 

Sitelinks

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21135388&oldid=2023025150"