SAM pointed domain containing ETS transcription factor (Q21135660)

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mammalian protein found in Homo sapiens

• prostate-specific Ets
• prostate epithelium-specific Ets transcription factor
• prostate-derived Ets factor
• SAM pointed domain-containing Ets transcription factor
• SPDEF

edit

Language	Label	Description	Also known as
English	SAM pointed domain containing ETS transcription factor	mammalian protein found in Homo sapiens	prostate-specific Ets prostate epithelium-specific Ets transcription factor prostate-derived Ets factor SAM pointed domain-containing Ets transcription factor SPDEF

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O95238

subclass of

protein

1 reference

stated in

UniProt

retrieved

1 December 2016

UniProt protein ID

O95238

part of

winged helix DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O95238

Winged helix-like DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O95238

Sterile alpha motif/pointed domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O95238

ETS transcription factor family

1 reference

based on heuristic

inferred from protein domain or family

Pointed domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O95238

encoded by

SPDEF

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O95238

molecular function

DNA-binding transcription factor activity

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

DNA binding

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O95238

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method or standard

IC

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IC

sequence-specific DNA binding

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

retrieved

8 April 2019

stated in

DNA-binding specificities of human transcription factors

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IDA

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method or standard

IBA

ISA

ISM

NAS

4 references

retrieved

8 April 2019

stated in

A census of human transcription factors: function, expression and evolution

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

NAS

retrieved

8 April 2019

stated in

A census of human transcription factors: function, expression and evolution

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

ISM

retrieved

8 April 2019

stated in

GOA

curator

Norwegian University of Science and Technology, Systems Biology team

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

ISA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IBA

cell component

nucleus

determination method or standard

IEA

IBA

4 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

O95238

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IBA

biological process

multicellular organism development

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

TAS

cell differentiation

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IBA

regulation of transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

negative regulation of transcription by RNA polymerase II

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

retrieved

8 April 2019

stated in

Prostate-derived Ets transcription factor (PDEF) is a potential prognostic marker in patients with prostate cancer

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IDA

negative regulation of cell fate commitment

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

lung goblet cell differentiation

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

intestinal epithelial cell development

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

O95238

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=O95238&geneProductId=UniProtKB:O95238

determination method or standard

IEA

positive regulation of cell fate commitment

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

positive regulation of transcription by RNA polymerase II

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IEA

positive regulation of apoptotic process

determination method or standard

IDA

1 reference

retrieved

8 April 2019

stated in

Prostate-derived Ets transcription factor (PDEF) is a potential prognostic marker in patients with prostate cancer

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IDA

regulation of transcription by RNA polymerase II

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O95238

determination method or standard

IBA

has part(s)

Ets domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O95238

Pointed domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O95238

Identifiers

RefSeq protein ID

NP_001239223

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

25803

NP_036523

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

25803

XP_005249045

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

25803

XP_011512759

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

25803

UniProt protein ID

O95238

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

O95238

Ensembl protein ID

ENSP00000363149

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000363149

ENSP00000442715

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000442715

PDB structure ID

2DKX

1 reference

stated in

UniProt

UniProt protein ID

O95238

retrieved

4 August 2016

language of work or name

English

 

Sitelinks

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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