Troponin T3, fast skeletal type (Q21135818)

http://www.ebi.ac.uk/interpro/protein/P45378

InterPro Release 71.0

reference URL

Troponin domain superfamily

1 reference

http://www.ebi.ac.uk/interpro/protein/P45378

InterPro Release 71.0

reference URL

1 reference

16 January 2019

1 reference

16 January 2019

calcium-dependent ATPase activity

2 references

27 March 2018

A recombinant monocysteine mutant (Ser to Cys-155) of fast skeletal troponin T: identification by cross-linking of a domain involved in a physiologically relevant interaction with troponins C and I

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

27 March 2018

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

actin binding

1 reference

8 April 2019

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

tropomyosin binding

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system

2 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

IMP

27 March 2018

A recombinant monocysteine mutant (Ser to Cys-155) of fast skeletal troponin T: identification by cross-linking of a domain involved in a physiologically relevant interaction with troponins C and I

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

troponin I binding

3 references

27 March 2018

Identification of a region of fast skeletal troponin T required for stabilization of the coiled-coil formation with troponin I

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

27 March 2018

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

27 March 2018

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

calcium-dependent protein binding

1 reference

8 April 2019

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

troponin C binding

2 references

27 March 2018

A recombinant monocysteine mutant (Ser to Cys-155) of fast skeletal troponin T: identification by cross-linking of a domain involved in a physiologically relevant interaction with troponins C and I

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

27 March 2018

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

calcium ion binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

protein binding

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

tropomyosin binding

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

IMP

8 April 2019

A recombinant monocysteine mutant (Ser to Cys-155) of fast skeletal troponin T: identification by cross-linking of a domain involved in a physiologically relevant interaction with troponins C and I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

troponin C binding

A recombinant monocysteine mutant (Ser to Cys-155) of fast skeletal troponin T: identification by cross-linking of a domain involved in a physiologically relevant interaction with troponins C and I

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

8 April 2019

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

calcium-dependent ATPase activity

A recombinant monocysteine mutant (Ser to Cys-155) of fast skeletal troponin T: identification by cross-linking of a domain involved in a physiologically relevant interaction with troponins C and I

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

8 April 2019

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

troponin I binding

Identification of a region of fast skeletal troponin T required for stabilization of the coiled-coil formation with troponin I

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

8 April 2019

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

8 April 2019

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

cell component

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

1 reference

8 April 2019

TAS

troponin complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

4 references

27 March 2018

IEA

27 March 2018

A recombinant monocysteine mutant (Ser to Cys-155) of fast skeletal troponin T: identification by cross-linking of a domain involved in a physiologically relevant interaction with troponins C and I

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

27 March 2018

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

27 March 2018

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

troponin complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

5 references

8 April 2019

IEA

8 April 2019

A recombinant monocysteine mutant (Ser to Cys-155) of fast skeletal troponin T: identification by cross-linking of a domain involved in a physiologically relevant interaction with troponins C and I

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

8 April 2019

Interaction of deletion mutants of troponins I and T: COOH-terminal truncation of troponin T abolishes troponin I binding and reduces Ca2+ sensitivity of the reconstituted regulatory system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

8 April 2019

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

regulation of muscle contraction

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

1 reference

8 April 2019

skeletal muscle contraction

IEA

1 reference

27 March 2018

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function

http://www.ebi.ac.uk/QuickGO/annotations?protein=P45378&geneProductId=UniProtKB:P45378

regulation of ATP-dependent activity

1 reference

8 April 2019

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

muscle filament sliding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

1 reference

8 April 2019

skeletal muscle contraction

TAS

muscle contraction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

sarcomere organization

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

cardiac muscle contraction

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45378

physically interacts with

tirasemtiv

object of statement has role

activation

1 reference

Open Targets Platform