Huntingtin interacting proteins are genetic modifiers of neurodegeneration (Q21145230)

Syntaxin 1A (brain)

1 reference

Synaptosomal-associated protein 25

1 reference

Ubiquitin specific peptidase 9, X chromosome

1 reference

Cullin 2

1 reference

Huntingtin

1 reference

Pyruvate kinase, muscle

1 reference

26S protease regulatory subunit 7

1 reference

1 reference

17

Cornelia Kurschner

Cornelia

Kurschner

1 reference

17 August 2022

1

Linda S

Kaltenbach

Linda S Kaltenbach

1 reference

17 August 2022

18

Lisa M

Ellerby

Lisa M Ellerby

1 reference

17 August 2022

Eliana Romero

2

Eliana

Romero

1 reference

17 August 2022

Robert R Becklin

3

Robert R

Becklin

1 reference

17 August 2022

Rakesh Chettier

4

Rakesh

Chettier

1 reference

17 August 2022

Russell Bell

5

Russell

Bell

1 reference

17 August 2022

Amit Phansalkar

6

Amit

Phansalkar

1 reference

17 August 2022

Andrew Strand

7

Andrew

Strand

1 reference

17 August 2022

Cameron Torcassi

8

Cameron

Torcassi

1 reference

17 August 2022

Justin Savage

9

Justin

Savage

1 reference

17 August 2022

Anthony Hurlburt

10

Anthony

Hurlburt

1 reference

17 August 2022

Guang-Ho Cha

11

Guang-Ho

Cha

1 reference

17 August 2022

Lubna Ukani

12

Lubna

Ukani

1 reference

17 August 2022

Cindy Lou Chepanoske

13

Cindy Lou

Chepanoske

1 reference

17 August 2022

Yuejun Zhen

14

Yuejun

Zhen

1 reference

17 August 2022

Sudhir Sahasrabudhe

15

Sudhir

Sahasrabudhe

1 reference

17 August 2022

James Olson

16

James

Olson

1 reference

17 August 2022

John M Peltier

19

John M

Peltier

1 reference

17 August 2022

Juan Botas

20

Juan

Botas

1 reference

17 August 2022

Robert E Hughes

21

Robert E

Hughes

1 reference

Creative Commons Attribution 4.0 International

17 August 2022

language of work or name

English

0 references

publication date

11 May 2007

0 references

published in

PLOS Genetics

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volume

3

0 references

issue

5

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page(s)

e82

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copyright license

start time

11 May 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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19 March 2017

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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

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19 March 2017

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Normal huntingtin function: an alternative approach to Huntington's disease

19 March 2017

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

19 March 2017

1 reference

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19 March 2017

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Huntingtin: alive and well and working in middle management

19 March 2017

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The hunt for huntingtin function: interaction partners tell many different stories

19 March 2017

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Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

19 March 2017

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Huntingtin interacts with a family of WW domain proteins

19 March 2017

1 reference

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Wild-type and mutant huntingtins function in vesicle trafficking in the secretory and endocytic pathways

19 March 2017

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19 March 2017

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Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH

12 September 2017

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Huntingtin-protein interactions and the pathogenesis of Huntington's disease

12 September 2017

1 reference

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Huntingtin bodies sequester vesicle-associated proteins by a polyproline-dependent interaction.

12 September 2017

1 reference

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Huntington's disease: a synaptopathy?

12 September 2017

1 reference

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The use of transgenic and knock-in mice to study Huntington's disease.

12 September 2017

1 reference

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How reliable are experimental protein-protein interaction data?

12 September 2017

1 reference

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Dying for a cause: invertebrate genetics takes on human neurodegeneration

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Mouse and fly models of neurodegeneration

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Identities of sequestered proteins in aggregates from cells with induced polyglutamine expression

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Recruitment and the role of nuclear localization in polyglutamine-mediated aggregation

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Crosstalk between huntingtin and syntaxin 1A regulates N-type calcium channels.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

The complete set of predicted genes from Saccharomyces cerevisiae in a readily usable form

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

On the relationship between senescence and age-related changes in two wild-type strains of Drosophila melanogaster

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Genetic suppression of polyglutamine toxicity in Drosophila

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

HEAT repeats in the Huntington's disease protein

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Progressive and selective striatal degeneration in primary neuronal cultures using lentiviral vector coding for a mutant huntingtin fragment

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Disruption of Axonal Transport by Loss of Huntingtin or Expression of Pathogenic PolyQ Proteins in Drosophila

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Identification of genes that modify ataxin-1-induced neurodegeneration.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866352

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

29 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/17500595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Huntingtin: Alive and Well and Working in Middle Management

1 reference

https://pubmed.ncbi.nlm.nih.gov/17500595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.0030082

1 reference

1 reference

1 reference

1 reference