ADAM metallopeptidase with thrombospondin type 1 motif 1 (Q21170793)

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mammalian protein found in Homo sapiens

A disintegrin and metalloproteinase with thrombospondin motifs 1
ADAM-TS 1
ADAMTS1
METH-1
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1
human metalloproteinase with thrombospondin type 1 motifs
ADAMTS-1
ADAM-TS1

Language	Label	Description	Also known as
English	ADAM metallopeptidase with thrombospondin type 1 motif 1	mammalian protein found in Homo sapiens	A disintegrin and metalloproteinase with thrombospondin motifs 1 ADAM-TS 1 ADAMTS1 METH-1 a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1 human metalloproteinase with thrombospondin type 1 motifs ADAMTS-1 ADAM-TS1

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

1 December 2016

UniProt protein ID

Peptidase M12B, ADAM-TS1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UHI8

Thrombospondin type-1 (TSP1) repeat superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UHI8

Metallopeptidase, catalytic domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UHI8

ADAMTS/ADAMTS-like

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Peptidase M12B, ADAM/reprolysin, protein family

1 reference

based on heuristic

inferred from protein domain or family

ADAM-TS Spacer 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

ADAM, cysteine-rich, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase M12B, propeptide family

1 reference

based on heuristic

inferred from protein domain or family

Thrombospondin type-1 (TSP1) repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

zinc ion binding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

metal ion binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

peptidase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

hydrolase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

metallopeptidase activity

determination method or standard

3 references

8 April 2019

METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

extracellular region

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

basement membrane

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

cytoplasmic vesicle

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

collagen-containing extracellular matrix

determination method or standard

1 reference

8 April 2019

Comprehensive proteomic characterization of stem cell-derived extracellular matrices

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

biological process

ovulation from ovarian follicle

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

heart trabecula formation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

kidney development

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

integrin-mediated signaling pathway

determination method or standard

1 reference

8 April 2019

Molecular cloning of a gene encoding a new type of metalloproteinase-disintegrin family protein with thrombospondin motifs as an inflammation associated gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

negative regulation of cell population proliferation

determination method or standard

1 reference

8 April 2019

METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

positive regulation of G1/S transition of mitotic cell cycle

determination method or standard

1 reference

8 April 2019

MiR-362-3p inhibits the proliferation and migration of vascular smooth muscle cells in atherosclerosis by targeting ADAMTS1.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

positive regulation of vascular associated smooth muscle cell proliferation

determination method or standard

1 reference

8 April 2019

MiR-362-3p inhibits the proliferation and migration of vascular smooth muscle cells in atherosclerosis by targeting ADAMTS1.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

positive regulation of vascular associated smooth muscle cell migration

determination method or standard

1 reference

8 April 2019

MiR-362-3p inhibits the proliferation and migration of vascular smooth muscle cells in atherosclerosis by targeting ADAMTS1.

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHI8

determination method or standard

Peptidase M12B, ADAM/reprolysin

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UHI8

ADAM, cysteine-rich

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UHI8

Thrombospondin type-1 (TSP1) repeat

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UHI8

ADAM-TS Spacer 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UHI8

Peptidase M12B, propeptide

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UHI8

Identifiers

MeSH descriptor ID

subject named as

ADAMTS1 Protein

0 references

D08.811.277.656.675.374.102.500.500

0 references

D09.400.430.500.500.500

0 references

D12.776.395.033.500.500

0 references

D12.776.860.300.085.500

0 references

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000284984

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000284984

ENSP00000403404

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000403404

ENSP00000429557

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000429557

ENSP00000431065

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000431065

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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