Exocyst complex component 8 (Q21173384)

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mammalian protein found in Homo sapiens

• exocyst complex component 8
• EXOC8
• exocyst complex 84 kDa subunit

edit

Language	Label	Description	Also known as
English	Exocyst complex component 8	mammalian protein found in Homo sapiens	exocyst complex component 8 EXOC8 exocyst complex 84 kDa subunit

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IYI6

part of

Cullin repeat-like-containing domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8IYI6

PH-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8IYI6

Exocyst complex component Exo84

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8IYI6

exocyst family

1 reference

Transporter Classification Database ID

1.F.2.1.2

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

pleckstrin homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Exocyst component Exo84, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IYI6

encoded by

EXOC8

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IYI6

molecular function

protein binding

determination method or standard

IPI

8 references

retrieved

9 May 2019

stated in

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IPI

retrieved

9 May 2019

stated in

SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IPI

retrieved

9 May 2019

stated in

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IPI

retrieved

9 May 2019

stated in

Towards a proteome-scale map of the human protein–protein interaction network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IPI

retrieved

9 May 2019

stated in

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IPI

retrieved

9 May 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IPI

retrieved

9 May 2019

stated in

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IPI

retrieved

9 May 2019

stated in

RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IPI

cell component

late endosome

determination method or standard

IDA

1 reference

retrieved

9 May 2019

stated in

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IDA

cell projection

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

membrane

determination method or standard

IDA

1 reference

retrieved

26 September 2017

stated in

Defining the membrane proteome of NK cells

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IYI6&geneProductId=UniProtKB:Q8IYI6

determination method or standard

IDA

growth cone

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

plasma membrane

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

TAS

exocyst

determination method or standard

IDA

IEA

3 references

retrieved

26 September 2017

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IYI6&geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

retrieved

26 September 2017

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IYI6&geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

retrieved

26 September 2017

stated in

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IYI6&geneProductId=UniProtKB:Q8IYI6

determination method or standard

IDA

cytoplasm

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

cytosol

determination method or standard

IDA

TAS

2 references

retrieved

9 May 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

TAS

retrieved

9 May 2019

stated in

GOA

curator

Human Protein Atlas

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IDA

perinuclear region of cytoplasm

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

cell leading edge

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

exocyst

determination method or standard

IBA

IDA

IEA

4 references

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

retrieved

9 May 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

retrieved

9 May 2019

stated in

The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IDA

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IBA

membrane

determination method or standard

HDA

1 reference

retrieved

9 May 2019

stated in

Defining the membrane proteome of NK cells

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

HDA

biological process

extracellular matrix disassembly

determination method or standard

IMP

1 reference

retrieved

9 May 2019

stated in

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IMP

endosome organization

determination method or standard

IMP

1 reference

retrieved

9 May 2019

stated in

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IMP

exocyst localization

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IBA

exocyst assembly

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IBA

protein transport

determination method or standard

IEA

1 reference

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

regulation of macroautophagy

determination method or standard

TAS

1 reference

retrieved

9 May 2019

stated in

RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

TAS

exocytosis

determination method or standard

IEA

2 references

retrieved

9 May 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

retrieved

9 May 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

transport

determination method or standard

IEA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

UniProt

UniProt protein ID

Q8IYI6

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IYI6&geneProductId=UniProtKB:Q8IYI6

determination method or standard

IEA

Golgi to plasma membrane transport

determination method or standard

IBA

1 reference

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IBA

protein localization

determination method or standard

IBA

1 reference

retrieved

9 May 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8IYI6

determination method or standard

IBA

has part(s)

Exocyst component Exo84, C-terminal

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8IYI6

pleckstrin homology domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8IYI6

Identifiers

RefSeq protein ID

NP_787072

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

149371

UniProt protein ID

Q8IYI6

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8IYI6

Ensembl protein ID

ENSP00000355605

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000355605

Transporter Classification Database ID

1.F.2.1.2

2 references

stated in

Transporter Classification database

retrieved

13 March 2020

stated in

Transporter Classification database

retrieved

29 April 2020

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21173384&oldid=2023036366"