Transcription factor AP-2 beta (Q21202951)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q92481

Transcription factor AP-2, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

sequence-specific DNA binding

protein dimerization activity

1 reference

8 April 2019

Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

protein homodimerization activity

1 reference

8 April 2019

Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

transcription corepressor activity

1 reference

27 March 2018

Transcription factor AP-2 regulates human insulin-like growth factor binding protein-5 gene expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

DNA-binding transcription factor activity

Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

8 April 2019

Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

The role of Sp1 and AP-2 in basal and protein kinase A--induced expression of mitochondrial serine:pyruvate aminotransferase in hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

chromatin binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

RNA polymerase II general transcription initiation factor activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

4 references

10 September 2018

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

7 November 2018

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

protein binding

5 references

8 April 2019

Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

cis-regulatory region sequence-specific DNA binding

1 reference

8 April 2019

Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

protein heterodimerization activity

1 reference

8 April 2019

Novel TFAP2B mutations that cause Char syndrome provide a genotype-phenotype correlation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

4 references

5 June 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

NAS

5 June 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

Norwegian University of Science and Technology, Systems Biology team

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

ISA

5 June 2018

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

transcription coactivator activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

transcription corepressor activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Transcription factor AP-2 regulates human insulin-like growth factor binding protein-5 gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

RNA polymerase II transcription regulatory region sequence-specific DNA binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

5 references

7 November 2018

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

NAS

7 November 2018

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

Norwegian University of Science and Technology, Systems Biology team

7 November 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

ISA

7 November 2018

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

7 November 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

DNA-binding transcription factor activity, RNA polymerase II-specific

A census of human transcription factors: function, expression and evolution

6 references

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

NAS

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

Norwegian University of Science and Technology, Systems Biology team

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

cell component

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

5 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

5 June 2018

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

5 June 2018

AP2 transcription factor induces apoptosis in retinoblastoma cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

5 June 2018

The role of Sp1 and AP-2 in basal and protein kinase A--induced expression of mitochondrial serine:pyruvate aminotransferase in hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

IC

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

1 reference

8 April 2019

TAS

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

AP2 transcription factor induces apoptosis in retinoblastoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

The role of Sp1 and AP-2 in basal and protein kinase A--induced expression of mitochondrial serine:pyruvate aminotransferase in hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

IC

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

negative regulation of neuron apoptotic process

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

retina layer formation

IEP

1 reference

8 April 2019

AP2 transcription factor induces apoptosis in retinoblastoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

regulation of insulin secretion

IEP

negative regulation of apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Comparative expression profiling identifies an in vivo target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

metanephric nephron development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

1 reference

5 June 2018

response to lithium ion

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92481&geneProductId=UniProtKB:Q92481

positive regulation of transcription, DNA-templated

positive regulation of neuron apoptotic process

1 reference

8 April 2019

AP2 transcription factor induces apoptosis in retinoblastoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

glucose metabolic process

3 references

8 April 2019

The transcription factor TFAP2B is associated with insulin resistance and adiposity in healthy adolescents

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Intronic polymorphisms within TFAP2B regulate transcriptional activity and affect adipocytokine gene expression in differentiated adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

sensory organ development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

regulation of cell differentiation

1 reference

8 April 2019

AP2 transcription factor induces apoptosis in retinoblastoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

negative regulation of transcription, DNA-templated

1 reference

8 April 2019

AP2 transcription factor induces apoptosis in retinoblastoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

negative regulation of cell population proliferation

1 reference

8 April 2019

AP2 transcription factor induces apoptosis in retinoblastoma cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

skin development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

apoptotic process

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

1 reference

8 April 2019

positive regulation of transcription by RNA polymerase II

ISS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

8 April 2019

The role of Sp1 and AP-2 in basal and protein kinase A--induced expression of mitochondrial serine:pyruvate aminotransferase in hepatocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92481

Transcription factor AP-2, C-terminal

has part(s)

1 reference

InterPro Release 71.0