BUB1B, mitotic checkpoint serine/threonine kinase (Q21494913)

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mammalian protein found in Mus musculus

budding uninhibited by benzimidazoles 1 beta
mitotic checkpoint kinase MAD3L
MAD3/BUB1-related protein kinase
mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Bub1b
BubR1
budding uninhibited by benzimidazoles 1 homolog, beta

Language	Label	Description	Also known as
English	BUB1B, mitotic checkpoint serine/threonine kinase	mammalian protein found in Mus musculus	budding uninhibited by benzimidazoles 1 beta mitotic checkpoint kinase MAD3L MAD3/BUB1-related protein kinase mitotic checkpoint serine/threonine-protein kinase BUB1 beta Bub1b BubR1 budding uninhibited by benzimidazoles 1 homolog, beta

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Mitotic spindle checkpoint protein Bub1/Mad3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1S0

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1S0

Mad3/Bub1 homology region 1, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

transferase activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

nucleotide binding

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

kinase activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

protein serine/threonine kinase activity

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

protein binding

determination method or standard

1 reference

14 February 2019

Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

outer kinetochore

determination method or standard

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

14 February 2019

Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

14 February 2019

Sequential assembly of centromeric proteins in male mouse meiosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

chromosome, centromeric region

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

determination method or standard

8 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

14 February 2019

Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

14 February 2019

Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

14 February 2019

Bub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

14 February 2019

The E4F protein is required for mitotic progression during embryonic cell cycles

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

determination method or standard

1 reference

10 September 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1S0&geneProductId=UniProtKB:Q9Z1S0

determination method or standard

biological process

phosphorylation

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

protein phosphorylation

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

determination method or standard

1 reference

14 February 2019

Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

protein localization to chromosome, centromeric region

determination method or standard

1 reference

14 February 2019

Sequential assembly of centromeric proteins in male mouse meiosis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

apoptotic process

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

meiotic sister chromatid cohesion, centromeric

determination method or standard

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z1S0

determination method or standard

protein localization to kinetochore

determination method or standard

1 reference

10 September 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z1S0&geneProductId=UniProtKB:Q9Z1S0

determination method or standard

Mad3/Bub1 homology region 1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1S0

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9Z1S0

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000037126

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000037126

Sitelinks

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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