Delta like non-canonical Notch ligand 1 (Q21495525)

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mammalian protein found in Mus musculus

fetal antigen 1
Pref-1
protein delta homolog 1
delta-like 1 homolog
Dlk1
adipocyte differentiation inhibitor protein
stromal cell derived protein 1
preadipocyte factor 1

Language	Label	Description	Also known as
English	Delta like non-canonical Notch ligand 1	mammalian protein found in Mus musculus	fetal antigen 1 Pref-1 protein delta homolog 1 delta-like 1 homolog Dlk1 adipocyte differentiation inhibitor protein stromal cell derived protein 1 preadipocyte factor 1

Statements

1 reference

25 May 2022

UniProt protein ID

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

EGF-like calcium-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

EGF-like, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

plasma membrane

determination method or standard

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

external side of plasma membrane

determination method or standard

1 reference

14 February 2019

Hematopoietic progenitors from early murine fetal liver possess hepatic differentiation potential

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

extracellular space

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

integral component of membrane

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

determination method or standard

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

biological process

regulation of gene expression

determination method or standard

1 reference

14 February 2019

Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

negative regulation of fat cell differentiation

determination method or standard

1 reference

14 February 2019

Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

post-embryonic development

determination method or standard

1 reference

14 February 2019

Gene dosage effects of the imprinted delta-like homologue 1 (dlk1/pref1) in development: implications for the evolution of imprinting

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

embryonic skeletal system development

determination method or standard

1 reference

14 February 2019

Gene dosage effects of the imprinted delta-like homologue 1 (dlk1/pref1) in development: implications for the evolution of imprinting

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

determination method or standard

1 reference

14 February 2019

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

osteoblast differentiation

determination method or standard

1 reference

14 February 2019

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

positive regulation of cytokine production

determination method or standard

1 reference

14 February 2019

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

bone mineralization

determination method or standard

1 reference

14 February 2019

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

multicellular organism growth

determination method or standard

1 reference

14 February 2019

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

positive regulation of bone resorption

determination method or standard

1 reference

24 April 2018

DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q09163&geneProductId=UniProtKB:Q09163

determination method or standard

negative regulation of vascular endothelial cell proliferation

determination method or standard

1 reference

14 February 2019

MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

cell differentiation

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

negative regulation of ossification

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

negative regulation of osteoblast differentiation

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

regulation of bone remodeling

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

negative regulation of bone remodeling

determination method or standard

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

negative regulation of Notch signaling pathway

determination method or standard

3 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

14 February 2019

The EGF-like proteins DLK1 and DLK2 function as inhibitory non-canonical ligands of NOTCH1 receptor that modulate each other's activities

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q09163

determination method or standard

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000063104

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000063104

ENSMUSP00000105467

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000105467

ENSMUSP00000105470

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000105470

ENSMUSP00000133530

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000133530

ENSMUSP00000134308

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000134308

ENSMUSP00000105472

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000105472

ENSMUSP00000133430

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000133430

ENSMUSP00000105469

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000105469

ENSMUSP00000105468

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000105468

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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