CAMP responsive element binding protein 1 (Q21498062)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01147

Basic-leucine zipper domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Coactivator CBP, pKID, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

DNA-binding transcription factor activity

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Multiple basic-leucine zipper proteins regulate induction of the mouse heme oxygenase-1 gene by arsenite

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

protein binding

6 references

14 February 2019

A role for brain-specific homeobox factor Bsx in the control of hyperphagia and locomotory behavior

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

MeCP2, a key contributor to neurological disease, activates and represses transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Hepatocyte Growth Factor Modulates Interleukin-6 Production in Bone Marrow Derived Macrophages: Implications for Inflammatory Mediated Diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Genome-wide map of nuclear protein degradation shows NCoR1 turnover as a key to mitochondrial gene regulation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Individual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanisms

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

CREBL2, interacting with CREB, induces adipogenesis in 3T3-L1 adipocytes

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

14 February 2019

Secalonic acid D alters the expression and phosphorylation of the transcription factors and their binding to cAMP response element in developing murine secondary palate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

CD40 stimulation induces Pax5/BSAP and EBF activation through a APE/Ref-1-dependent redox mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

sequence-specific DNA binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

A twist code determines the onset of osteoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

DNA-binding transcription activator activity, RNA polymerase II-specific

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

cell component

nucleus

Endogenous prolactin-releasing peptide regulates food intake in rodents

12 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

CREBL2, interacting with CREB, induces adipogenesis in 3T3-L1 adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Proteolytic cleavage of ALF into alpha- and beta-subunits that form homologous and heterologous complexes with somatic TFIIA and TRF2 in male germ cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

ATF4-CREB1 transcription factor complex

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

nucleoplasm

TAS

transcription regulator complex

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01147&geneProductId=UniProtKB:Q01147

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01147&geneProductId=UniProtKB:Q01147

21 June 2018

Secalonic acid D alters the expression and phosphorylation of the transcription factors and their binding to cAMP response element in developing murine secondary palate

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01147&geneProductId=UniProtKB:Q01147

transcription regulator complex

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Secalonic acid D alters the expression and phosphorylation of the transcription factors and their binding to cAMP response element in developing murine secondary palate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

cellular response to nerve growth factor stimulus

IBA

biological process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

positive regulation of lipid biosynthetic process

1 reference

14 February 2019

CREBL2, interacting with CREB, induces adipogenesis in 3T3-L1 adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

rhythmic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

1 reference

14 February 2019

cellular response to insulin-like growth factor stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

mammary gland development

1 reference

14 February 2019

Hypothalamic 3',5'-cyclic adenosine monophosphate response element-binding protein loss causes anterior pituitary hypoplasia and dwarfism in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

type I pneumocyte differentiation

1 reference

14 February 2019

cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

positive regulation of multicellular organism growth

1 reference

14 February 2019

Hypothalamic 3',5'-cyclic adenosine monophosphate response element-binding protein loss causes anterior pituitary hypoplasia and dwarfism in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

response to L-glutamate

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

lung saccule development

1 reference

14 February 2019

cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

lung epithelium development

1 reference

14 February 2019

cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

cellular response to transforming growth factor beta stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

response to glucagon

1 reference

14 February 2019

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

response to nicotine

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

positive regulation of osteoclast differentiation

1 reference

14 February 2019

Tmem64 modulates calcium signaling during RANKL-mediated osteoclast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

memory

1 reference

5 June 2018

Increasing CRTC1 function in the dentate gyrus during memory formation or reactivation increases memory strength without compromising memory quality

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01147&geneProductId=UniProtKB:Q01147

transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01147&geneProductId=UniProtKB:Q01147

1 reference

21 June 2018

positive regulation of transcription, DNA-templated

1 reference

14 February 2019

CREBL2, interacting with CREB, induces adipogenesis in 3T3-L1 adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

lactation

1 reference

14 February 2019

Hypothalamic 3',5'-cyclic adenosine monophosphate response element-binding protein loss causes anterior pituitary hypoplasia and dwarfism in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

positive regulation of fat cell differentiation

1 reference

14 February 2019

CREBL2, interacting with CREB, induces adipogenesis in 3T3-L1 adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

1 reference

14 February 2019

cellular response to hepatocyte growth factor stimulus

1 reference

14 February 2019

Hepatocyte Growth Factor Modulates Interleukin-6 Production in Bone Marrow Derived Macrophages: Implications for Inflammatory Mediated Diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

positive regulation of cardiac muscle tissue development

1 reference

14 February 2019

Neuregulin-1β induces embryonic stem cell cardiomyogenesis via ErbB3/ErbB2 receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

protein stabilization

1 reference

14 February 2019

CREBL2, interacting with CREB, induces adipogenesis in 3T3-L1 adipocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

cellular response to platelet-derived growth factor stimulus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

secretory granule organization

1 reference

14 February 2019

cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

regulation of cell size

1 reference

14 February 2019

Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

pituitary gland development

1 reference

14 February 2019

Hypothalamic 3',5'-cyclic adenosine monophosphate response element-binding protein loss causes anterior pituitary hypoplasia and dwarfism in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

response to hypoxia

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

axonogenesis

1 reference

14 February 2019

Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

cellular response to growth factor stimulus

1 reference

14 February 2019

A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

human ageing

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

response to activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

cellular response to zinc ion

1 reference

14 February 2019

Neurulation and neurite extension require the zinc transporter ZIP12 (slc39a12)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

cellular response to fatty acid

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

positive regulation of hormone secretion

1 reference

14 February 2019

Hypothalamic 3',5'-cyclic adenosine monophosphate response element-binding protein loss causes anterior pituitary hypoplasia and dwarfism in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

positive regulation of transcription by RNA polymerase II

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

4 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01147&geneProductId=UniProtKB:Q01147

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01147&geneProductId=UniProtKB:Q01147

21 June 2018

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01147&geneProductId=UniProtKB:Q01147

21 June 2018

Deregulated protein kinase A signaling and myospryn expression in muscular dystrophy

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01147&geneProductId=UniProtKB:Q01147

cellular response to leukemia inhibitory factor

IEP

1 reference

14 February 2019

miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

IEP

memory

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Increasing CRTC1 function in the dentate gyrus during memory formation or reactivation increases memory strength without compromising memory quality

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

positive regulation of transcription by RNA polymerase II

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

14 February 2019

Deregulated protein kinase A signaling and myospryn expression in muscular dystrophy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

cellular response to retinoic acid

1 reference

14 February 2019

The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01147

has part(s)

Coactivator CBP, pKID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q01147

Basic-leucine zipper domain

1 reference

InterPro Release 71.0