Fibroblast growth factor 2 (Q21985348)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P15655

Cytokine IL1/FGF

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P15655

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

heparin binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

1 reference

9 May 2019

protein binding

4 references

9 May 2019

Inactivation of fibroblast growth factor binding protein 3 causes anxiety-related behaviors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Characterization of FGFRL1, a novel fibroblast growth factor (FGF) receptor preferentially expressed in skeletal tissues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

nuclear receptor coactivator activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

chemoattractant activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

growth factor activity

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

9 May 2019

FGF2-induced upregulation of DNA polymerase-delta p12 subunit in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

fibroblast growth factor receptor binding

receptor-receptor interaction

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

cell component

extracellular space

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Fibroblast growth factor signaling regulates pillar cell development in the organ of corti

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

nucleus

release of sequestered calcium ion into cytosol

biological process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

1 reference

9 May 2019

positive regulation of protein kinase B signaling

1 reference

9 May 2019

C3G regulates the size of the cerebral cortex neural precursor population

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of protein phosphorylation

1 reference

9 May 2019

FGF2-induced upregulation of DNA polymerase-delta p12 subunit in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

negative regulation of fibroblast migration

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

hyaluronan catabolic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of endothelial cell chemotaxis to fibroblast growth factor

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of MAP kinase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

substantia nigra development

1 reference

9 May 2019

Fibroblast growth factor (FGF)-2 and FGF receptor 3 are required for the development of the substantia nigra, and FGF-2 plays a crucial role for the rescue of dopaminergic neurons after 6-hydroxydopamine lesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

negative regulation of blood vessel endothelial cell migration

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

corticotropin hormone secreting cell differentiation

1 reference

9 May 2019

Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

organ induction

1 reference

9 May 2019

Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of phospholipase C activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

stem cell development

1 reference

9 May 2019

Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of epithelial cell proliferation

1 reference

9 May 2019

Angiogenic factors stimulate tubular branching morphogenesis of sonic hedgehog-deficient lungs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of canonical Wnt signaling pathway

1 reference

9 May 2019

C3G regulates the size of the cerebral cortex neural precursor population

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

human ageing

Ensembl genome database project

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

glial cell differentiation

1 reference

9 May 2019

Functions of fibroblast growth factor (FGF)-2 and FGF-5 in astroglial differentiation and blood-brain barrier permeability: evidence from mouse mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

cardiac muscle cell proliferation

TAS

1 reference

9 May 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

Developmental FunctionaL Annotation at Tufts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

regulation of retinal cell programmed cell death

TAS

1 reference

9 May 2019

Neurotrophic signaling in normal and degenerating rodent retinas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

mammary gland epithelial cell differentiation

1 reference

9 May 2019

The int-2 gene product acts as a growth factor and substitutes for basic fibroblast growth factor in promoting the differentiation of a normal mouse mammary epithelial cell line

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

cell migration involved in sprouting angiogenesis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

regulation of cell cycle

1 reference

9 May 2019

Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of phosphatidylinositol 3-kinase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of endothelial cell migration

1 reference

9 May 2019

Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

1 reference

9 May 2019

chondroblast differentiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of gene expression

1 reference

9 May 2019

Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of osteoblast differentiation

1 reference

9 May 2019

Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

response to axon injury

1 reference

9 May 2019

Regulation of neuronal death and calcitonin gene-related peptide by fibroblast growth factor-2 and FGFR3 after peripheral nerve injury: evidence from mouse mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

angiogenesis

Angiogenic factors stimulate tubular branching morphogenesis of sonic hedgehog-deficient lungs

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

14 February 2019

14 February 2019

Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

14 February 2019

Aminopeptidase A is a functional target in angiogenic blood vessels

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of cell fate specification

1 reference

9 May 2019

Crucial role of vHNF1 in vertebrate hepatic specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

regulation of endothelial cell chemotaxis to fibroblast growth factor

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of cerebellar granule cell precursor proliferation

1 reference

9 May 2019

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

phosphatidylinositol biosynthetic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

thyroid-stimulating hormone-secreting cell differentiation

1 reference

9 May 2019

Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

inositol phosphate biosynthetic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

negative regulation of wound healing

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

1 reference

9 May 2019

negative regulation of cell population proliferation

positive regulation of transcription by RNA polymerase II

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Msx1 controls inductive signaling in mammalian tooth morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Protease nexin-1 is expressed at the mouse met-/mesencephalic junction and FGF signaling regulates its promoter activity in primary met-/mesencephalic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of cell population proliferation

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Fibroblast growth factor receptor signaling promotes radial glial identity and interacts with Notch1 signaling in telencephalic progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

Ensembl genome database project

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Shox2-deficient mice exhibit a rare type of incomplete clefting of the secondary palate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive chemotaxis

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of ERK1 and ERK2 cascade

fibroblast growth factor receptor signaling pathway

3 references

growth factor dependent regulation of skeletal muscle satellite cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

8 references

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Angiogenic factors stimulate tubular branching morphogenesis of sonic hedgehog-deficient lungs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Caveolin-1 knockout mice show an impaired angiogenic response to exogenous stimuli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Aminopeptidase A is a functional target in angiogenic blood vessels

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

9 May 2019

Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of vascular associated smooth muscle cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of vascular endothelial cell proliferation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

paracrine signaling

Ensembl genome database project

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15655&geneProductId=UniProtKB:P15655

positive regulation of DNA biosynthetic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

positive regulation of endothelial cell chemotaxis

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15655

1 reference

9 May 2019