VANGL planar cell polarity 2 (Q21981325)

http://www.ebi.ac.uk/interpro/protein/Q91ZD4

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

1 reference

25 May 2022

1 reference

25 May 2022

14 references

9 May 2019

Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Rack1 is required for Vangl2 membrane localization and planar cell polarity signaling while attenuating canonical Wnt activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Vangl2, the planar cell polarity protein, is complexed with postsynaptic density protein PSD-95 [corrected]

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

integral component of membrane

IPI

cell component

3 references

9 May 2019

Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

4 references

9 May 2019

Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Wnt5a functions in planar cell polarity regulation in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

14 February 2019

Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

14 February 2019

Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: effect of the Lp mutation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

14 February 2019

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

1 reference

9 May 2019

Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

1 reference

9 May 2019

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

basolateral plasma membrane

IDA

1 reference

9 May 2019

Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

IDA

apical plasma membrane

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

COPII-coated ER to Golgi transport vesicle

IDA

1 reference

9 May 2019

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

1 reference

9 May 2019

Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: effect of the Lp mutation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

hair follicle development

IBA

biological process

1 reference

9 May 2019

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

dopaminergic neuron axon guidance

1 reference

9 May 2019

Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

1 reference

9 May 2019

Ciliary proteins link basal body polarization to planar cell polarity regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

planar dichotomous subdivision of terminal units involved in lung branching morphogenesis

1 reference

9 May 2019

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

establishment of epithelial cell polarity

1 reference

9 May 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

non-canonical Wnt signaling pathway

1 reference

9 May 2019

Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

regulation of establishment of planar polarity

1 reference

9 May 2019

Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

lateral sprouting involved in lung morphogenesis

1 reference

9 May 2019

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

inner ear receptor cell stereocilium organization

3 references

9 May 2019

Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Ciliary proteins link basal body polarization to planar cell polarity regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Syndecan 4 interacts genetically with Vangl2 to regulate neural tube closure and planar cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

regulation of actin cytoskeleton organization

1 reference

9 May 2019

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

somatic stem cell population maintenance

1 reference

9 May 2019

Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

convergent extension involved in axis elongation

1 reference

9 May 2019

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis

1 reference

9 May 2019

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

positive regulation of JUN kinase activity

1 reference

9 May 2019

MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

muscular septum morphogenesis

1 reference

9 May 2019

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

serotonergic neuron axon guidance

1 reference

9 May 2019

Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

establishment of planar polarity

3 references

14 February 2019

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

14 February 2019

Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

14 February 2019

Epidermal wound repair is regulated by the planar cell polarity signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

membranous septum morphogenesis

1 reference

9 May 2019

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

somatic stem cell division

1 reference

9 May 2019

Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

planar cell polarity pathway involved in heart morphogenesis

1 reference

9 May 2019

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

cardiac vascular smooth muscle cell differentiation

1 reference

9 May 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

heparan sulfate proteoglycan biosynthetic process

1 reference

9 May 2019

Syndecan 4 interacts genetically with Vangl2 to regulate neural tube closure and planar cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

glomerulus development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

establishment of body hair planar orientation

1 reference

9 May 2019

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

planar cell polarity pathway involved in axis elongation

1 reference

9 May 2019

Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

establishment of planar polarity involved in neural tube closure

1 reference

9 May 2019

Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

outflow tract septum morphogenesis

1 reference

9 May 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

planar cell polarity pathway involved in neural tube closure

7 references

9 May 2019

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

The novel mouse mutant, chuzhoi, has disruption of Ptk7 protein and exhibits defects in neural tube, heart and lung development and abnormal planar cell polarity in the ear.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Epidermal wound repair is regulated by the planar cell polarity signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

epicardial cell to mesenchymal cell transition

1 reference

9 May 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

1 reference

9 May 2019

Cardiovascular defects associated with abnormalities in midline development in the Loop-tail mouse mutant

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

regulation of Wnt signaling pathway

1 reference

9 May 2019

Wdpcp, a PCP protein required for ciliogenesis, regulates directional cell migration and cell polarity by direct modulation of the actin cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 references

9 May 2019

Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Cordon-bleu is a conserved gene involved in neural tube formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Syndecan 4 interacts genetically with Vangl2 to regulate neural tube closure and planar cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Wnt5a functions in planar cell polarity regulation in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

inner ear receptor cell development

1 reference

9 May 2019

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway

cochlea morphogenesis

6 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Wnt5a functions in planar cell polarity regulation in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Epidermal wound repair is regulated by the planar cell polarity signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

Rho protein signal transduction

1 reference

9 May 2019

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

establishment or maintenance of epithelial cell apical/basal polarity

1 reference

9 May 2019

Asymmetric distribution of prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner ear

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

1 reference

9 May 2019

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

cell migration involved in kidney development

1 reference

9 May 2019

Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

branching involved in blood vessel morphogenesis

1 reference

9 May 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

post-anal tail morphogenesis

1 reference

9 May 2019

PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

convergent extension involved in neural plate elongation

3 references

9 May 2019

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

convergent extension involved in organogenesis

1 reference

9 May 2019

Wnt5a functions in planar cell polarity regulation in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

anterior/posterior pattern specification

1 reference

9 May 2019

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

digestive tract morphogenesis

1 reference

9 May 2019

Sfrp controls apicobasal polarity and oriented cell division in developing gut epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

planar cell polarity pathway involved in axon guidance

1 reference

9 May 2019

Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

non-motile cilium assembly

1 reference

9 May 2019

Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

Wnt signaling pathway, planar cell polarity pathway

3 references

14 February 2019

Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

14 February 2019

Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

14 February 2019

Wnt5a functions in planar cell polarity regulation in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

establishment of planar polarity

4 references

9 May 2019

Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tract

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Epidermal wound repair is regulated by the planar cell polarity signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

Wnt signaling pathway, planar cell polarity pathway

IBA

4 references

9 May 2019

Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Wnt5a functions in planar cell polarity regulation in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91ZD4