Euchromatic histone methyltransferase 1 (Q21982953)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5DW34

Histone-lysine N-methyltransferase EHMT1

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q5DW34

SET domain, protein family

1 reference

Pre-SET domain, protein family

1 reference

Ankyrin repeat-containing domain, protein family

1 reference

Ankyrin repeat, protein family

1 reference

histone methyltransferase activity (H3-K9 specific)

1 reference

25 May 2022

1 reference

25 May 2022

histone methyltransferase activity (H3-K27 specific)

1 reference

14 February 2019

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

1 reference

14 February 2019

transferase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

1 reference

14 February 2019

zinc ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

1 reference

14 February 2019

C2H2 zinc finger domain binding

1 reference

14 February 2019

Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

histone-lysine N-methyltransferase activity

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

protein binding

5 references

14 February 2019

A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

14 February 2019

G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

14 February 2019

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

14 February 2019

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

14 February 2019

Rif1 maintains telomere length homeostasis of ESCs by mediating heterochromatin silencing

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

methyltransferase activity

ISO

p53 binding

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins

5 references

14 February 2019

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

14 February 2019

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

chromosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

1 reference

14 February 2019

biological process

embryo development

1 reference

27 February 2018

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q5DW34&geneProductId=UniProtKB:Q5DW34

peptidyl-lysine monomethylation

1 reference

14 February 2019

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

histone lysine methylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

1 reference

14 February 2019

DNA methylation

1 reference

14 February 2019

G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

methylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

1 reference

14 February 2019

response to fungicide

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

negative regulation of transcription by RNA polymerase II

1 reference

14 February 2019

Opposing LSD1 complexes function in developmental gene activation and repression programmes

GOA

curator

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

peptidyl-lysine dimethylation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

ISO

14 February 2019

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

negative regulation of transcription, DNA-templated

1 reference

14 February 2019

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

histone H3-K9 methylation

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

histone H3-K27 methylation

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

chromatin organization

regulation of embryonic development

ISO

1 reference

14 February 2019

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34

positive regulation of cold-induced thermogenesis

1 reference

14 February 2019

EHMT1 controls brown adipose cell fate and thermogenesis through the PRDM16 complex.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q5DW34