Integrin alpha L (Q21983362)

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mammalian protein found in Mus musculus

Itgal
leukocyte function-associated molecule 1 alpha chain
LFA-1A
CD11 antigen-like family member A
Ly-15
leukocyte adhesion glycoprotein LFA-1 alpha chain
alpha L integrin
lymphocyte antigen 15
integrin alpha-L
lymphocyte function associated antigen 1, alpha polypeptide

Language	Label	Description	Also known as
English	Integrin alpha L	mammalian protein found in Mus musculus	Itgal leukocyte function-associated molecule 1 alpha chain LFA-1A CD11 antigen-like family member A Ly-15 leukocyte adhesion glycoprotein LFA-1 alpha chain alpha L integrin lymphocyte antigen 15 integrin alpha-L lymphocyte function associated antigen 1, alpha polypeptide

Statements

1 reference

25 May 2022

UniProt protein ID

Integrin domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24063

integrin alpha chain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24063

von Willebrand factor A-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24063

Integrin alpha, N-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24063

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

von Willebrand factor, type A, protein family

1 reference

based on heuristic

inferred from protein domain or family

Integrin alpha beta-propellor, protein family

1 reference

based on heuristic

inferred from protein domain or family

Integrin alpha-2, protein family

1 reference

based on heuristic

inferred from protein domain or family

FG-GAP repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

Integrin alpha chain, C-terminal cytoplasmic region, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

metal ion binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

ICAM-3 receptor activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

cell adhesion molecule binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

protein-containing complex binding

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

protein heterodimerization activity

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

integral component of membrane

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

integrin alphaL-beta2 complex

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

cell-cell junction

determination method

1 reference

14 February 2019

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

integrin complex

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

immunological synapse

determination method

1 reference

14 February 2019

A single class II myosin modulates T cell motility and stopping, but not synapse formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

plasma membrane

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

biological process

leukocyte cell-cell adhesion

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

14 February 2019

Heat stable antigen (mouse CD24) supports myeloid cell binding to endothelial and platelet P-selectin

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

14 February 2019

Differential, LFA-1-sensitive effects of antibodies to nectadrin, the heat-stable antigen, on B lymphoblast aggregation and signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

14 February 2019

A single class II myosin modulates T cell motility and stopping, but not synapse formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

positive regulation of calcium-mediated signaling

determination method

1 reference

14 February 2019

Differential, LFA-1-sensitive effects of antibodies to nectadrin, the heat-stable antigen, on B lymphoblast aggregation and signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

activated T cell proliferation

determination method

1 reference

14 February 2019

Deficiency of CD11b or CD11d results in reduced staphylococcal enterotoxin-induced T cell response and T cell phenotypic changes

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

positive regulation of cell-cell adhesion

determination method

1 reference

14 February 2019

Heat-stable antigen is a costimulatory molecule for CD4 T cell growth

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

receptor clustering

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

cell surface receptor signaling pathway

determination method

1 reference

14 February 2019

Differential, LFA-1-sensitive effects of antibodies to nectadrin, the heat-stable antigen, on B lymphoblast aggregation and signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

determination method

2 references

positive regulation of T cell proliferation

determination method

1 reference

14 February 2019

Heat-stable antigen is a costimulatory molecule for CD4 T cell growth

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

regulation of cell-cell adhesion

determination method

1 reference

14 February 2019

Differential, LFA-1-sensitive effects of antibodies to nectadrin, the heat-stable antigen, on B lymphoblast aggregation and signal transduction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

integrin-mediated signaling pathway

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

cell-matrix adhesion

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P24063

determination method

cell-cell adhesion

determination method

1 reference

24 April 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P24063&geneProductId=UniProtKB:P24063

determination method

Integrin alpha chain, C-terminal cytoplasmic region, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24063

von Willebrand factor, type A

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24063

Integrin alpha-2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24063

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24063

Integrin alpha beta-propellor

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P24063

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000131847

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000131847

ENSMUSP00000101913

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000101913

ENSMUSP00000112591

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000112591

ENSMUSP00000113396

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000113396

ENSMUSP00000113946

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000113946

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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