Dedicator of cyto-kinesis 2 (Q21983880)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Mus musculus

• Dock2
• Protein Hch
• dedicator of cytokinesis protein 2

edit

Language	Label	Description	Also known as
English	Dedicator of cyto-kinesis 2	mammalian protein found in Mus musculus	Dock2 Protein Hch dedicator of cytokinesis protein 2

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q8C3J5

part of

Dedicator of cytokinesis protein 2

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8C3J5

SH3-like domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8C3J5

Armadillo-type fold

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8C3J5

C2 domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8C3J5

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Dedicator of cytokinesis, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DHR-1 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

DHR-2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

house mouse

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q8C3J5

encoded by

Dock2

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q8C3J5

molecular function

GTPase activator activity

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

guanyl-nucleotide exchange factor activity

determination method or standard

IEA

2 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8C3J5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IEA

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IEA

T cell receptor binding

determination method or standard

ISS

IEA

ISO

3 references

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8C3J5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

ISS

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

ISO

retrieved

14 February 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IEA

cell component

cytoplasm

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8C3J5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IEA

cytoskeleton

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8C3J5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IEA

endomembrane system

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8C3J5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IEA

membrane

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8C3J5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IEA

biological process

positive regulation of phagocytosis

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

GOA

curator

UniProt

UniProt protein ID

Q8C3J5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

small GTPase mediated signal transduction

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IEA

alpha-beta T cell activation

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

membrane raft polarization

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

negative thymic T cell selection

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

T cell proliferation

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

chemotaxis

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

alpha-beta T cell proliferation

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

macropinocytosis

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

GOA

curator

UniProt

UniProt protein ID

Q8C3J5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

cytoskeleton organization

determination method or standard

IDA

1 reference

retrieved

14 February 2019

stated in

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IDA

myeloid dendritic cell activation involved in immune response

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization

GOA

curator

UniProt

UniProt protein ID

Q8C3J5

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

positive thymic T cell selection

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

establishment of T cell polarity

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

immunological synapse formation

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

actin cytoskeleton organization

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IEA

T cell activation

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IMP

positive regulation of Rac protein signal transduction

determination method or standard

IC

1 reference

retrieved

14 February 2019

stated in

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IC

positive regulation of GTPase activity

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8C3J5

determination method or standard

IEA

has part(s)

Dedicator of cytokinesis, N-terminal domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8C3J5

SH3 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8C3J5

DHR-2 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8C3J5

DHR-1 domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8C3J5

Identifiers

RefSeq protein ID

NP_203538

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

94176

XP_017170351

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

94176

UniProt protein ID

Q8C3J5

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q8C3J5

Ensembl protein ID

ENSMUSP00000090884

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000090884

ENSMUSP00000098915

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000098915

ENSMUSP00000098916

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000098916

ENSMUSP00000116893

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000116893

 

Sitelinks

Wikipedia(0 entries)

edit

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21983880&oldid=2023230423"