Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis (Q22010222)

beta-glucuronidase activity

GOA release 2020-03-11

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GOA release 2020-03-11

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I Vlodavsky

1

Israel

Vlodavsky

1 reference

6 February 2023

Y Friedmann

2

Yael

Friedmann

1 reference

6 February 2023

M Elkin

3

Michael

Elkin

1 reference

6 February 2023

H Aingorn

4

Helena

Aingorn

1 reference

6 February 2023

R Atzmon

5

Ruth

Atzmon

1 reference

6 February 2023

R Ishai-Michaeli

6

Rivka

Ishai-Michaeli

1 reference

6 February 2023

M Bitan

7

Menachem

Bitan

1 reference

6 February 2023

O Pappo

8

Orit

Pappo

1 reference

6 February 2023

T Peretz

9

Tuvia

Peretz

1 reference

6 February 2023

I Michal

10

Israel

Michal

1 reference

6 February 2023

L Spector

11

Larissa

Spector

1 reference

6 February 2023

I Pecker

12

Iris

Pecker

1 reference

Proteoglycans: structures and interactions

6 February 2023

language of work or name

English

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publication date

July 1999

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published in

Nature Medicine

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volume

5

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issue

7

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page(s)

793-802

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cites work

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7 January 2021

Integral membrane heparan sulfate proteoglycans

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Glycosaminoglycans: molecular properties, protein interactions, and role in physiological processes

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The role of proteoglycans in cell adhesion, migration and proliferation

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The coordinated regulation of heparan sulfate, syndecans and cell behavior

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Cell biology of arterial proteoglycans.

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Heparan sulfate degradation: relation to tumor invasive and metastatic properties of mouse B16 melanoma sublines

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Heparanases and tumor metastasis

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Evidence that sulphated polysaccharides inhibit tumour metastasis by blocking tumour-cell-derived heparanases

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Suppression of experimental autoimmune diseases and prolongation of allograft survival by treatment of animals with low doses of heparins

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7 January 2021

Heparanase activity expressed by platelets, neutrophils, and lymphoma cells releases active fibroblast growth factor from extracellular matrix

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7 January 2021

Extracellular sequestration and release of fibroblast growth factor: a regulatory mechanism?

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7 January 2021

Lipoprotein lipase enhances binding of lipoproteins to heparan sulfate on cell surfaces and extracellular matrix

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7 January 2021

Human platelet heparanase: purification, characterization and catalytic activity

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7 January 2021

CXC chemokines connective tissue activating peptide-III and neutrophil activating peptide-2 are heparin/heparan sulfate-degrading enzymes

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7 January 2021

Partial sequence of human platelet heparitinase and evidence of its ability to polymerize

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7 January 2021

Immunochemical localization of heparanase in mouse and human melanomas

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7 January 2021

Immunoselection of GRP94/endoplasmin from a KNRK cell-specific lambda gt11 library using antibodies directed against a putative heparanase amino-terminal peptide

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7 January 2021

Purification and characterization of placental heparanase and its expression by cultured cytotrophoblasts

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7 January 2021

Thrombin receptor overexpression in malignant and physiological invasion processes

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7 January 2021

Acquisition of high metastatic capacity after in vitro fusion of a nonmetastatic tumor line with a bone marrow-derived macrophage

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7 January 2021

Substrate specificity of heparanases from human hepatoma and platelets

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7 January 2021

Endothelial cell heparanase modulation of lipoprotein lipase activity. Evidence that heparan sulfate oligosaccharide is an extracellular chaperone

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7 January 2021

Degradation of sulfated proteoglycans in the subendothelial extracellular matrix by human platelet heparitinase

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7 January 2021

Degradation of heparan sulfate in the subendothelial extracellular matrix by a readily released heparanase from human neutrophils. Possible role in invasion through basement membranes

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7 January 2021

Activated T lymphocytes produce a matrix-degrading heparan sulphate endoglycosidase

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7 January 2021

Maintenance on extracellular matrix and expression of heparanase activity by human ovarian carcinoma cells from biopsy specimens

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7 January 2021

Structural biochemistry and activation of matrix metalloproteases

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7 January 2021

Type IV collagenases in tumor invasion and metastasis

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7 January 2021

Biology and biochemistry of proteinases in tumor invasion.

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7 January 2021

Sequential degradation of heparan sulfate in the subendothelial extracellular matrix by highly metastatic lymphoma cells

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7 January 2021

Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

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7 January 2021

Modulation of fibroblast growth factor-2 receptor binding, dimerization, signaling, and angiogenic activity by a synthetic heparin-mimicking polyanionic compound

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7 January 2021

Endothelial cell-derived basic fibroblast growth factor: synthesis and deposition into subendothelial extracellular matrix

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7 January 2021

Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression

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7 January 2021