Efficacy and safety of metformin during pregnancy in women with gestational diabetes mellitus or polycystic ovary syndrome: A systematic review (Q22252361)

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Efficacy and safety of metformin during pregnancy in women with gestational diabetes mellitus or polycystic ovary syndrome: a systematic review

Language	Label	Description	Also known as
English	Efficacy and safety of metformin during pregnancy in women with gestational diabetes mellitus or polycystic ovary syndrome: A systematic review	scientific article	Efficacy and safety of metformin during pregnancy in women with gestational diabetes mellitus or polycystic ovary syndrome: a systematic review

Statements

scholarly article

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systematic review

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based on heuristic

inferred from title

Efficacy and safety of metformin during pregnancy in women with gestational diabetes mellitus or polycystic ovary syndrome: A systematic review (English)

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gestational diabetes

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polycystic ovary syndrome

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based on heuristic

inferred from title

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based on heuristic

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human pregnancy

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based on heuristic

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systematic review

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based on heuristic

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polycystic ovary

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author name string

Maria-Elena Lautatzis

1

author given names

Maria-Elena

author last names

Lautatzis

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PubMed publication ID

29 March 2023

Dimitrios G. Goulis

2

author given names

Dimitrios G

author last names

Goulis

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PubMed publication ID

29 March 2023

Maria Vrontakis

3

author given names

Maria

author last names

Vrontakis

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PubMed publication ID

29 March 2023

language of work or name

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publication date

November 2013

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62

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11

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1522-1534

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Continuation of metformin in the first trimester of women with polycystic ovarian syndrome is not associated with increased perinatal morbidity

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https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of hepatic gluconeogenesis by metformin. Synergism with insulin.

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin--an update

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https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Gestational diabetes: the consequences of not treating

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Oral hypoglycemic agents vs insulin in management of gestational diabetes: a systematic review and metaanalysis

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin treatment for Type 2 diabetes in pregnancy?

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin compared with insulin in the management of gestational diabetes mellitus: a randomized clinical trial

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

The administration of metformin during pregnancy reduces polycystic ovary syndrome related gestational complications

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Introduction of metformin for gestational diabetes mellitus in clinical practice: Has it had an impact?

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Placental passage of metformin in women with polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of gestational diabetes by metformin plus diet in patients with polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin in the treatment of infertility in polycystic ovarian syndrome: an alternative perspective

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin therapy throughout pregnancy reduces the development of gestational diabetes in women with polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin-induced resumption of normal menses in 39 of 43 (91%) previously amenorrheic women with the polycystic ovary syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired glucose tolerance in pregnant women with polycystic ovary syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment--metformin

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Gestational diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metabolic effects of metformin in non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy of metformin in non-insulin-dependent diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Lactic acidosis in patients with diabetes treated with metformin

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin for the treatment of the polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of treatment of gestational diabetes mellitus on pregnancy outcomes

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Clomiphene, Metformin, or Both for Infertility in the Polycystic Ovary Syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin versus insulin for the treatment of gestational diabetes

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of in utero and early-life conditions on adult health and disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin reduces abortion in pregnant women with polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Neonatal outcome in polycystic ovarian syndrome patients treated with metformin during pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Pregnancy outcomes among women with polycystic ovary syndrome treated with metformin

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Height, weight, and motor-social development during the first 18 months of life in 126 infants born to 109 mothers with polycystic ovary syndrome who conceived on and continued metformin through pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin reduces pregnancy complications without affecting androgen levels in pregnant polycystic ovary syndrome women: results of a randomized study

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Combined lifestyle modification and metformin in obese patients with polycystic ovary syndrome. A randomized, placebo-controlled, double-blind multicentre study

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of metformin in polycystic ovary syndrome: a systematic review

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Population pharmacokinetics of metformin in late pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

On the potential of metformin to prevent preterm delivery in women with polycystic ovary syndrome - an epi-analysis

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Does continuous use of metformin throughout pregnancy improve pregnancy outcomes in women with polycystic ovarian syndrome?

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Prevention of gestational diabetes mellitus by continuing metformin therapy throughout pregnancy in women with polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of pregnancy on the pharmacokinetics of metformin

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin use and diabetic pregnancy-has its time come?

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

A 10-year retrospective analysis of pregnancy outcome in pregestational Type 2 diabetes: comparison of insulin and oral glucose-lowering agents

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Pregnancy outcomes in women with gestational diabetes treated with metformin or insulin: a case-control study

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin for gestational diabetes in routine clinical practice.

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin should be considered in the treatment of gestational diabetes: a prospective randomised study

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of metformin on glucose metabolism in the splanchnic bed

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin in polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Contraindications to use of metformin. Age and creatinine clearance need to be taken into consideration

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Impact of insulin resistance on pregnancy complications and outcome in women with polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Continuation of metformin reduces early pregnancy loss in obese Pakistani women with polycystic ovarian syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of metformin-diet intervention before and throughout pregnancy on obstetric and neonatal outcomes in patients with polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence-based and potential benefits of metformin in the polycystic ovary syndrome: a comprehensive review

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin Versus Placebo from First Trimester to Delivery in Polycystic Ovary Syndrome: A Randomized, Controlled Multicenter Study

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin improves pregnancy and live-birth rates in women with polycystic ovary syndrome (PCOS): a multicenter, double-blind, placebo-controlled randomized trial

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: a randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of metformin on early pregnancy loss in the polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects.

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Oral hypoglycemic agents for gestational diabetes mellitus?

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of metformin and insulin in the treatment of gestational diabetes: a retrospective, case-control study

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

A risk-benefit assessment of metformin in type 2 diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Oral Antidiabetic Agents

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin in gestational diabetes: the offspring follow-up (MiG TOFU): body composition at 2 years of age.

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Gestational diabetes. Incidence, maternal characteristics, and perinatal outcome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism of metformin action in non-insulin-dependent diabetes

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of metformin on carbohydrate and lipoprotein metabolism in NIDDM patients

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Biguanides and NIDDM

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Impaired glucose tolerance in adolescent offspring of diabetic mothers. Relationship to fetal hyperinsulinism

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin: a multitasking medication

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of metformin use in pregnant patients with polycystic ovary syndrome

1 reference

https://api.crossref.org/works/10.1016%2FJ.METABOL.2013.06.006

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.METABOL.2013.06.006

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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