complement factor properdin (Q22677535)

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mammalian protein found in Homo sapiens

• properdin P factor, complement
• properdin
• CFP
• complement factor P

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Language	Label	Description	Also known as
English	complement factor properdin	mammalian protein found in Homo sapiens	properdin P factor, complement properdin CFP complement factor P

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P27918

subclass of

protein

1 reference

stated in

UniProt

retrieved

1 December 2016

UniProt protein ID

P27918

part of

Thrombospondin type-1 (TSP1) repeat superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P27918

Thrombospondin type-1 (TSP1) repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P27918

encoded by

CFP

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P27918

molecular function

protein binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

Complement factor P is a ligand for the natural killer cell-activating receptor NKp46.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

IPI

serine-type endopeptidase activity

determination method

TAS

1 reference

retrieved

1 January 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27918&geneProductId=UniProtKB:P27918

determination method

TAS

cell component

extracellular matrix

determination method

IDA

1 reference

retrieved

17 October 2017

stated in

Proteomics characterization of extracellular space components in the human aorta

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27918&geneProductId=UniProtKB:P27918

determination method

IDA

endoplasmic reticulum lumen

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

TAS

extracellular region

determination method

IEA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P27918

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

IEA

extracellular space

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Sequence-based analysis of properdin deficiency: identification of point mutations in two phenotypic forms of an X-linked immunodeficiency

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

TAS

specific granule lumen

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

TAS

tertiary granule lumen

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

TAS

collagen-containing extracellular matrix

determination method

HDA

1 reference

retrieved

8 April 2019

stated in

Proteomics characterization of extracellular space components in the human aorta

GOA

curator

British Heart Foundation

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

HDA

biological process

immune response

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Sequence-based analysis of properdin deficiency: identification of point mutations in two phenotypic forms of an X-linked immunodeficiency

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

TAS

regulation of complement activation

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

TAS

defense response to bacterium

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

Sequence-based analysis of properdin deficiency: identification of point mutations in two phenotypic forms of an X-linked immunodeficiency

GOA

curator

Proteome Inc.

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

TAS

immune system process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P27918

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

IEA

complement activation

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

TAS

protein O-linked fucosylation

determination method

TAS

1 reference

retrieved

17 October 2017

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27918&geneProductId=UniProtKB:P27918

determination method

TAS

complement activation, alternative pathway

determination method

IEA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P27918

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

IEA

innate immune response

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

P27918

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

IEA

neutrophil degranulation

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27918

determination method

TAS

proteolysis

determination method

IEA

1 reference

retrieved

1 January 2018

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=P27918&geneProductId=UniProtKB:P27918

determination method

IEA

has part(s)

Thrombospondin type-1 (TSP1) repeat

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P27918

Identifiers

MeSH descriptor ID

D011414

subject named as

Properdin

0 references

MeSH tree code

D12.776.124.486.274.965

0 references

D12.776.124.790.223.624

0 references

D12.776.377.715.182.624

0 references

RefSeq protein ID

NP_001138724

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5199

NP_002612

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5199

XP_016885064

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

5199

UniProt protein ID

P27918

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

P27918

Ensembl protein ID

ENSP00000247153

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000247153

ENSP00000380189

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000380189

ENSP00000366204

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000366204

ENSP00000418258

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000418258

PDB structure ID

1W0R

1 reference

stated in

UniProt

UniProt protein ID

P27918

retrieved

2 August 2016

language of work or name

English

1W0S

1 reference

stated in

UniProt

UniProt protein ID

P27918

retrieved

2 August 2016

language of work or name

English

UMLS CUI

C0033452

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

stated in

UMLS 2023

retrieved

24 May 2023

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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