Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene (Q34005475)

30 July 2017

title

Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene (English)

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30 July 2017

Kexiao Guo

1

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30 July 2017

Alan Pourpak

2

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30 July 2017

Kara Beetz-Rogers

3

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30 July 2017

Vijay Gokhale

4

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30 July 2017

Daekyu Sun

5

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30 July 2017

Laurence H Hurley

6

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30 July 2017

language of work or name

English

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publication date

2 August 2007

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Journal of the American Chemical Society

30 July 2017

published in

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30 July 2017

volume

129

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30 July 2017

issue

33

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30 July 2017

page(s)

10220-10228

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G-quadruplexes in promoters throughout the human genome

30 July 2017

cites work

1 reference

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Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter

5 July 2018

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Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb)

5 July 2018

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The G691S RET polymorphism increases glial cell line-derived neurotrophic factor-induced pancreatic cancer cell invasion by amplifying mitogen-activated protein kinase signaling.

5 July 2018

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Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents

5 July 2018

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Putative DNA quadruplex formation within the human c-kit oncogene

5 July 2018

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RET proto-oncogene: a review and update of genotype-phenotype correlations in hereditary medullary thyroid cancer and associated endocrine tumors

5 July 2018

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Telomestatin and diseleno sapphyrin bind selectively to two different forms of the human telomeric G-quadruplex structure

5 July 2018

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RET tyrosine kinase signaling in development and cancer

5 July 2018

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Genetic aberrance of sporadic MEN 2A component tumours: analysis of RET.

5 July 2018

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The RET proto-oncogene: a molecular therapeutic target in thyroid cancer

5 July 2018

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Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells

5 July 2018

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Propeller-type parallel-stranded G-quadruplexes in the human c-myc promoter

5 July 2018

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5 July 2018

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The cationic porphyrin TMPyP4 down-regulates c-MYC and human telomerase reverse transcriptase expression and inhibits tumor growth in vivo

5 July 2018

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Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription

5 July 2018

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CD of single-stranded, double-stranded, and G-quartet nucleic acids in complexes with a single-stranded DNA-binding protein

5 July 2018

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Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus

5 July 2018

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The RET proto-oncogene in human cancers

5 July 2018

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Sp1 and Sp3 transactivate the RET proto-oncogene promoter

5 July 2018

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Induction of duplex to G-quadruplex transition in the c-myc promoter region by a small molecule

5 July 2018

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The solution structure and internal motions of a fragment of the cytidine-rich strand of the human telomere

5 July 2018

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A DNA polymerase stop assay for G-quadruplex-interactive compounds

5 July 2018

1 reference

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A 5'-CG-3'-rich region in the promoter of the transcriptionally frequently silenced RET protooncogene lacks methylated cytidine residues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566970

An intramolecular i-motif: the solution structure and base-pair opening kinetics of d(5mCCT3CCT3ACCT3CC)

5 July 2018

1 reference

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Centromeric pyrimidine strands fold into an intercalated motif by forming a double hairpin with a novel T:G:G:T tetrad: solution structure of the d(TCCCGTTTCCA) dimer

5 July 2018

1 reference

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Cytosine-specific chemical probing of DNA using bromide and monoperoxysulfate

5 July 2018

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Multiple single-stranded cis elements are associated with activated chromatin of the human c-myc gene in vivo

5 July 2018

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A tetrameric DNA structure with protonated cytosine.cytosine base pairs

5 July 2018

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Intramolecular folding of a fragment of the cytosine-rich strand of telomeric DNA into an i-motif

5 July 2018

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Cloning and expression of the ret proto-oncogene encoding a tyrosine kinase with two potential transmembrane domains

5 July 2018

1 reference

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Monovalent cation-induced structure of telomeric DNA: the G-quartet model

5 July 2018

1 reference

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The ret proto-oncogene is consistently expressed in human pheochromocytomas and thyroid medullary carcinomas

5 July 2018

1 reference

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A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene

5 July 2018

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Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566970

Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566970

Telomestatin, a potent telomerase inhibitor that interacts quite specifically with the human telomeric intramolecular g-quadruplex

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2566970

Expression of the RET proto-oncogene in normal human tissues, pheochromocytomas, and other tumors of neural crest origin

29 October 2018

1 reference

12 December 2020

Spectroscopic evidence for the formation of four-stranded solution structure of oligodeoxycytidine phosphorothioate

1 reference

12 December 2020

A nuclease hypersensitive element in the human c-myc promoter adopts several distinct i-tetraplex structures

1 reference

12 December 2020

The dynamic character of the G-quadruplex element in the c-MYC promoter and modification by TMPyP4

1 reference

12 December 2020

Human telomeric C–strand tetraplexes

1 reference

12 December 2020

Identifiers

DOI

10.1021/JA072185G

1 reference

30 July 2017

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30 July 2017

1 reference