Genistein: does it prevent or promote breast cancer? (Q34018154)

30 July 2017

2 references

21 February 2023

19 January 2024

Genistein: does it prevent or promote breast cancer? (English)

1 reference

30 July 2017

2 references

21 February 2023

19 January 2024

1 reference

30 January 2021

1 reference

17 September 2019

1 reference

16 October 2020

1 reference

17 July 2021

Leena Hilakivi-Clarke

series ordinal

2

object named as

L Hilakivi-Clarke

1 reference

30 July 2017

K B Bouker

1

1 reference

30 July 2017

publication date

1 August 2000

12 references

30 July 2017

13 March 2019

3 April 2019

17 June 2019

9 August 2019

20 August 2019

17 September 2019

16 October 2020

30 January 2021

17 July 2021

21 February 2023

19 January 2024

8

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Environmental Health Perspectives

inferred from page(s)

published in

12 references

30 July 2017

13 March 2019

3 April 2019

17 June 2019

9 August 2019

20 August 2019

17 September 2019

16 October 2020

30 January 2021

17 July 2021

21 February 2023

19 January 2024

108

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30 July 2017

issue

8

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30 July 2017

page(s)

701-708

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Inhibition of CYP1A1 enzyme activity in mouse hepatoma cell culture by soybean isoflavones

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Prepubertal exposure to zearalenone or genistein reduces mammary tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Induction of apoptosis and inhibition of c-erbB-2 in MDA-MB-435 cells by genistein.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Maternal exposure to genistein during pregnancy increases carcinogen-induced mammary tumorigenesis in female rat offspring.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Differentiation between vasculoprotective and uterotrophic effects of ligands with different binding affinities to estrogen receptors alpha and beta

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

The risk of breast cancer following reproductive surgery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Chemoprevention of N-nitroso-N-methylurea-induced rat mammary carcinogenesis by soy foods or biochanin A.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Body size in different periods of life and breast cancer risk in post-menopausal women

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Effect of soybean phytoestrogen intake on low density lipoprotein oxidation resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Human topoisomerase II function, tyrosine phosphorylation and cell cycle checkpoints

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Evolution, nutrition, intestinal microflora, and prevention of cancer: a hypothesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

The chemopreventive properties of soy isoflavonoids in animal models of breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Case-control study of phyto-oestrogens and breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Differential ligand activation of estrogen receptors ERalpha and ERbeta at AP1 sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Genistein inhibits proliferation and in vitro invasive potential of human prostatic cancer cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Tamoxifen treatment for breast cancer: concept to gold standard.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Inhibition of protein tyrosine phosphorylation in endothelial cells: relationship to antiproliferative action of genistein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Tofu and risk of breast cancer in Asian-Americans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Stimulatory influence of soy protein isolate on breast secretion in pre- and postmenopausal women.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Diet, nutrition, and avoidable cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Molecular effects of genistein on estrogen receptor mediated pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Role of 17 beta-hydroxysteroid dehydrogenase type 1 in endocrine and intracrine estradiol biosynthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Growth factors in breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Migration patterns and breast cancer risk in Asian-American women

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Soy intake and cancer risk: a review of the in vitro and in vivo data

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Lignans and flavonoids inhibit aromatase enzyme in human preadipocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

EGF receptor expression, regulation, and function in breast cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Thrombotic mechanisms in atherosclerosis: potential impact of soy proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Diet and breast cancer in Shanghai and Tianjin, China

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

A prospective study of endogenous estrogens and breast cancer in postmenopausal women

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Genistein, a dietary-derived inhibitor of in vitro angiogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Breast cancer: cause and prevention

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Effect of neonatally administered estrogen or prolactin on normal and neoplastic mammary growth and serum estradiol-17 beta level in rats.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Chemoprevention of N-nitroso-N-methylurea-induced mammary cancers by pretreatment with 17 beta-estradiol and progesterone

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Occurrence of breast cancer in relation to diet and reproductive history: a case-control study in Fukuoka, Japan

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Body size at different periods of life and breast cancer risk

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Effects of perinatal exposure to a synthetic estrogen and progestin on mammary tumorigenesis in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Genistein, a specific inhibitor of tyrosine-specific protein kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Sex hormones in women in rural China and in Britain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Factors associated with obtaining nipple aspirate fluid: analysis of 1428 women and literature review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Cerumen phenotype and proliferative epithelium in breast fluids of U.S.-born vs. immigrant Asian women: a possible genetic-environmental interaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Dietary Soybean Isolate and Methionine Supplementation Affect Mammary Tumor Progression in Rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Dietary effects on breast-cancer risk in Singapore

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Tyrosine phosphorylation of membrane proteins mediates cellular invasion by transformed cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

The lessons of life: keynote address to the nutrition and cancer conference

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Phytoestrogens: Adverse Effects on Reproduction in California Quail

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Cancer epidemiology in populations of the United States--with emphasis on Hawaii and California--and Japan

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Phytoestrogen interaction with estrogen receptors in human breast cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Soy isoflavones exert modest hormonal effects in premenopausal women

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Dietary genistein: perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Soy intake and risk of breast cancer in Asians and Asian Americans

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Effect of soymilk consumption on serum estrogen concentrations in premenopausal Japanese women

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Maternal genistein exposure mimics the effects of estrogen on mammary gland development in female mouse offspring.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Flavonoids inhibit estrogen binding to rat alpha-fetoprotein

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

The effective free fraction of estradiol and xenoestrogens in human serum measured by whole cell uptake assays: physiology of delivery modifies estrogenic activity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Diet and premenopausal bilateral breast cancer: a case-control study

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Regulation of sex hormone-binding globulin production by isoflavonoids and patterns of isoflavonoid conjugation in HepG2 cell cultures

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Antiestrogens are partial estrogen agonists for prolactin production in primary pituitary cultures

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Dietary intervention study to assess estrogenicity of dietary soy among postmenopausal women

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1638285

Genistein alters the ontogeny of mammary gland development and protects against chemically-induced mammary cancer in rats

29 October 2018

1 reference

12 December 2020

Cytotoxic activity of epidermal growth factor-genistein against breast cancer cells

1 reference

12 December 2020

Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo

1 reference

12 December 2020

Genistein exerts multiple suppressive effects on human breast carcinoma cells

1 reference

12 December 2020

Timing of dietary fat exposure and mammary tumorigenesis: role of estrogen receptor and protein kinase C activity

1 reference

12 December 2020

Mechanisms of action of the soy isoflavone genistein: emerging role for its effects via transforming growth factor beta signaling pathways

1 reference

12 December 2020

The interaction in the immature mouse of potent oestrogens with coumestrol, genistein and other utero-vaginotrophic compounds of low potency

1 reference

12 December 2020

Steroid and phyto-oestrogen binding to sheep uterine receptors in vitro

1 reference

12 December 2020

The relationship between estrogen levels and diets of Caucasian American and Oriental immigrant women

1 reference

12 December 2020

Cancer in first and second generation Americans

1 reference

12 December 2020

Acute and subacute effects of naturally occurring estrogens on luteinizing hormone secretion in the ovariectomized rat: Part 1

1 reference

12 December 2020

Genistein arrests cell cycle progression at G2-M

1 reference

12 December 2020

Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women

1 reference

12 December 2020

Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases

1 reference

12 December 2020

Genistein suppresses mammary cancer in rats

1 reference

12 December 2020

Biological effects of isoflavones in young women: importance of the chemical composition of soyabean products

1 reference

12 December 2020

Premenopausal breast cancer after in-utero exposure to stilboestrol

1 reference

12 December 2020

Effects of soya consumption for one month on steroid hormones in premenopausal women: implications for breast cancer risk reduction

1 reference

12 December 2020

Inhibition of 17 -Hydroxysteroid Oxidoreductase by Flavonoids in Breast and Prostate Cancer Cells

1 reference

12 December 2020

Biphasic effects of genistein on bone tissue in the ovariectomized, lactating rat model

1 reference

12 December 2020

Effects of soy-protein supplementation on epithelial proliferation in the histologically normal human breast

1 reference

12 December 2020

Regulation of c-fos transcription by chemopreventive isoflavonoids and lignans in MDA-MB-468 breast cancer cells

1 reference

12 December 2020

Prepubertal genistein treatment modulates TGF-alpha, EGF and EGF-receptor mRNAs and proteins in the rat mammary gland

1 reference

12 December 2020

Effects of soy isoflavones on estrogen and phytoestrogen metabolism in premenopausal women.

1 reference

12 December 2020

Urinary excretion of isoflavonoids and the risk of breast cancer

1 reference

12 December 2020

Maternal and neonatal phytoestrogens in Japanese women during birth

1 reference

12 December 2020

Selective effects of genistein, a soybean isoflavone, on B-lymphopoiesis and bone loss caused by estrogen deficiency

1 reference

12 December 2020

3rd International Symposium on the Role of Soy in Preventing and Treating Chronic Disease. Washington DC, USA. October 31-November 3, 1999. Proceedings and abstracts

1 reference

12 December 2020

Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells

1 reference

12 December 2020

Estrogenic and antiproliferative properties of genistein and other flavonoids in human breast cancer cells in vitro

1 reference

12 December 2020

Intrauterine environment and breast cancer risk in women: a population-based study

1 reference

12 December 2020

Dietary genistein exerts estrogenic effects upon the uterus, mammary gland and the hypothalamic/pituitary axis in rats

1 reference

12 December 2020

Mitogenic growth factors in breast fluid obtained from healthy women: evaluation of biological and extraneous sources of variability

1 reference

12 December 2020

Effects of dietary menhaden oil, soy, and a cyclooxygenase inhibitor on human breast cancer cell growth and metastasis in nude mice

1 reference

12 December 2020

Identifiers

DOI

10.1289/EHP.00108701

1 reference

30 July 2017

1 reference

30 July 2017

1 reference