Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms (Q34025149)

30 July 2017

title

Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms (English)

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30 July 2017

Anja Zeigerer

16

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Victor E. Koteliansky

23

object named as

Victor Koteliansky

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30 July 2017

Akin Akinc

1

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30 July 2017

William Querbes

2

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30 July 2017

Soma De

3

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30 July 2017

June Qin

4

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Maria Frank-Kamenetsky

5

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K Narayanannair Jayaprakash

6

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Muthusamy Jayaraman

7

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Kallanthottathil G Rajeev

8

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30 July 2017

William L Cantley

9

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30 July 2017

J Robert Dorkin

10

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James S Butler

11

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30 July 2017

Liuliang Qin

12

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Timothy Racie

13

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Andrew Sprague

14

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Eugenio Fava

15

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Michael J Hope

17

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Marino Zerial

18

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Dinah W Y Sah

19

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Kevin Fitzgerald

20

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Mark A Tracy

21

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Muthiah Manoharan

22

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Antonin de Fougerolles

24

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Martin A Maier

25

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30 July 2017

publication date

11 May 2010

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30 July 2017

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30 July 2017

volume

18

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30 July 2017

issue

7

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30 July 2017

page(s)

1357-1364

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Lipid-like materials for low-dose, in vivo gene silencing

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Development of lipidoid-siRNA formulations for systemic delivery to the liver

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Delivery vehicles for small interfering RNA in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Tumor-targeted delivery of siRNA by self-assembled nanoparticles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Administration in non-human primates of escalating intravenous doses of targeted nanoparticles containing ribonucleotide reductase subunit M2 siRNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

RGD-based strategies for selective delivery of therapeutics and imaging agents to the tumour vasculature

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Recycling of apolipoprotein E and lipoprotein lipase through endosomal compartments in vivo.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Design and synthesis of novel amphiphilic dendritic galactosides for selective targeting of liposomes to the hepatic asialoglycoprotein receptor.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Asialoglycoprotein receptor deficiency in mice lacking the minor receptor subunit

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

The binding of desialylated glycoproteins by plasma membranes of rat liver

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

The LDL-receptor-related protein, LRP, is an apolipoprotein E-binding protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Effects of apolipoproteins A-IV and A-I on the uptake of phospholipid liposomes by hepatocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Liposomes containing synthetic lipid derivatives of poly(ethylene glycol) show prolonged circulation half-lives in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Rational design of cationic lipids for siRNA delivery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

RNAi-mediated gene silencing in non-human primates.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Effective targeting of liposomes to liver and hepatocytes in vivo by incorporation of a Plasmodium amino acid sequence

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Design and synthesis of novel N-acetylgalactosamine-terminated glycolipids for targeting of lipoproteins to the hepatic asialoglycoprotein receptor

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Determination of the upper size limit for uptake and processing of ligands by the asialoglycoprotein receptor on hepatocytes in vitro and in vivo.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911264

Interactions of liposomes and lipid-based carrier systems with blood proteins: Relation to clearance behaviour in vivo

29 October 2018

1 reference

12 December 2020

The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI

1 reference

12 December 2020

The role of apolipoprotein E in the elimination of liposomes from blood by hepatocytes in the mouse

1 reference

12 December 2020

Gold nanoparticles as a versatile platform for optimizing physicochemical parameters for targeted drug delivery

1 reference

12 December 2020

A membrane receptor protein for asialoglycoproteins

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12 December 2020

Identifiers

DOI

10.1038/MT.2010.85

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30 July 2017

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30 July 2017

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