Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase. (Q34034787)

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20 February 2020

title

Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase (English)

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20 February 2020

2

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Kenji Hashimoto

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Jesse Alt

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Barbara S Slusher

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Camilo Rojas

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20 February 2020

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Ajit G Thomas

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20 February 2020

author name string

James F Berry

1

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20 February 2020

Bridget Duvall

3

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20 February 2020

Niyada Hin

4

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Rana Rais

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20 February 2020

Takashi Tsukamoto

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publication date

16 September 2012

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ACS Medicinal Chemistry Letters

20 February 2020

published in

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volume

3

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issue

10

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page(s)

839-843

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Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice

20 February 2020

cites work

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From revolution to evolution: the glutamate hypothesis of schizophrenia and its implication for treatment

28 July 2018

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Recent advances in the discovery of D-amino acid oxidase inhibitors and their therapeutic utility in schizophrenia

28 July 2018

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Glutamatergic theories of schizophrenia.

28 July 2018

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High dose D-serine in the treatment of schizophrenia

28 July 2018

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Discovery, SAR, and pharmacokinetics of a novel 3-hydroxyquinolin-2(1H)-one series of potent D-amino acid oxidase (DAAO) inhibitors

28 July 2018

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The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors

28 July 2018

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In vitro and in vivo pharmacological profile of AS057278, a selective d-amino acid oxidase inhibitor with potential anti-psychotic properties

28 July 2018

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Structural basis of D-DOPA oxidation by D-amino acid oxidase: alternative pathway for dopamine biosynthesis

28 July 2018

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Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection

28 July 2018

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Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine

28 July 2018

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The behavioral and neurochemical effects of a novel D-amino acid oxidase inhibitor compound 8 [4H-thieno [3,2-b]pyrrole-5-carboxylic acid] and D-serine.

29 October 2018

1 reference

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Synthesis and biological evaluation of D-amino acid oxidase inhibitors.

29 October 2018

1 reference

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D-amino-acid oxidase is involved in D-serine-induced nephrotoxicity

29 October 2018

1 reference

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Sodium benzoate attenuates D-serine induced nephrotoxicity in the rat.

29 October 2018

1 reference

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29 October 2018

Identifiers

DOI

10.1021/ML300212A

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20 February 2020

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20 February 2020

PubMed publication ID

23243487

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