Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate (Q34058435)

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English	Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Human insulin receptor monoclonal antibody undergoes high affinity binding to human brain capillaries in vitro and rapid transcytosis through the blood-brain barrier in vivo in the primate (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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blood–brain barrier

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based on heuristic

inferred from title

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based on heuristic

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monoclonal antibody

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William M Pardridge

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Kang YS

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

Buciak JL

3

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Europe PubMed Central

PubMed publication ID

30 July 2017

Yang J

4

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Europe PubMed Central

PubMed publication ID

30 July 2017

publication date

1 June 1995

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Europe PubMed Central

PubMed publication ID

30 July 2017

Pharmaceutical Research

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Europe PubMed Central

PubMed publication ID

30 July 2017

12

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Europe PubMed Central

PubMed publication ID

30 July 2017

6

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30 July 2017

807-816

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Europe PubMed Central

PubMed publication ID

30 July 2017

Relationship between plasma and cerebrospinal fluid insulin levels of dogs

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Human brain microvascular DR-antigen

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Absorptive-mediated endocytosis of cationized albumin and a beta-endorphin-cationized albumin chimeric peptide by isolated brain capillaries. Model system of blood-brain barrier transport

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood-brain barrier transcytosis of insulin in developing rabbits

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Pharmacokinetics and saturable blood-brain barrier transport of biotin bound to a conjugate of avidin and a monoclonal antibody to the transferrin receptor

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Morphology of blood-brain interfaces

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Pharmacologic effects in vivo in brain by vector-mediated peptide drug delivery.

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Human blood-brain barrier insulin receptor

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Transport of recombinant CD4 through the rat blood-brain barrier in vivo.

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Quantitative anatomy of the cerebral vascular bed with especial emphasis on homogeneity and inhomogeneity in small ports of the gray and white matter

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Transferrin receptor on endothelium of brain capillaries

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Biotin delivery to brain with a covalent conjugate of avidin and a monoclonal antibody to the transferrin receptor

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Ultrastructural study on the interaction of insulin-albumin-gold complex with mouse brain microvascular endothelial cells

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Macromolecular permeability across the blood-nerve and blood-brain barriers

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Use of neutral avidin improves pharmacokinetics and brain delivery of biotin bound to an avidin-monoclonal antibody conjugate

1 reference

https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Human blood-brain barrier transferrin receptor

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Internalization of the human insulin receptor. The insulin-independent pathway

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Quantitative autoradiographic evidence for insulin receptors in the choroid plexus of the rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

based on heuristic

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Selective transport of an anti-transferrin receptor antibody through the blood-brain barrier in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

based on heuristic

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Monoclonal antibodies to the insulin receptor mimic metabolic effects of insulin but do not stimulate receptor autophosphorylation in transfected NIH 3T3 fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

based on heuristic

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Analysis of lymphopoietic stem cells with a monoclonal antibody to the rat transferrin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

based on heuristic

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Receptor-mediated transcytosis of transferrin across the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

based on heuristic

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Cross-linking of a B25 azidophenylalanine insulin derivative to the carboxyl-terminal region of the alpha-subunit of the insulin receptor. Identification of a new insulin-binding domain in the insulin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

based on heuristic

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Blood-brain barrier penetration and in vivo activity of an NGF conjugate

1 reference

https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Identification of epitopes on the human insulin receptor reacting with rabbit polyclonal antisera and mouse monoclonal antibodies

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https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

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Deletion of residues 485-599 from the human insulin receptor abolishes antireceptor antibody binding and influences tyrosine kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

based on heuristic

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A comparative study of the peroxidase-antiperoxidase method and an avidin-biotin complex method for studying polypeptide hormones with radioimmunoassay antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/7667183

12 December 2020

based on heuristic

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Identifiers

10.1023/A:1016244500596

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

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