Thrombospondin1 deficiency reduces obesity-associated inflammation and improves insulin sensitivity in a diet-induced obese mouse model (Q34062545)

30 July 2017

title

Thrombospondin1 deficiency reduces obesity-associated inflammation and improves insulin sensitivity in a diet-induced obese mouse model (English)

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30 July 2017

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Yanzhang Li

1

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30 July 2017

Xiaopeng Tong

2

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30 July 2017

Courtney Rumala

3

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30 July 2017

Kate Clemons

4

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30 July 2017

Shuxia Wang

5

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30 July 2017

language of work or name

English

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publication date

24 October 2011

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

10

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30 July 2017

page(s)

e26656

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

24 October 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Thrombospondin-4 Regulates Vascular Inflammation and Atherogenesis

5 July 2018

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CD11c expression in adipose tissue and blood and its role in diet-induced obesity

5 July 2018

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Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals

5 July 2018

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Thrombospondin 1 promotes tumor macrophage recruitment and enhances tumor cell cytotoxicity of differentiated U937 cells

5 July 2018

1 reference

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Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance

5 July 2018

1 reference

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A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways

5 July 2018

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

5 July 2018

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TLR4 links innate immunity and fatty acid-induced insulin resistance

5 July 2018

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Modulation of angiogenesis during adipose tissue development in murine models of obesity

5 July 2018

1 reference

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Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans

5 July 2018

1 reference

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Thrombospondin-1 is a major activator of TGF-beta in fibrotic renal disease in the rat in vivo.

5 July 2018

1 reference

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

5 July 2018

1 reference

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Obesity is associated with macrophage accumulation in adipose tissue

5 July 2018

1 reference

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Genes induced by growth hormone in a model of adipogenic differentiation.

5 July 2018

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Isolation of up- or down-regulated genes in PPARgamma-expressing NIH-3T3 cells during differentiation into adipocytes

5 July 2018

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Thrombospondins as matricellular modulators of cell function

5 July 2018

1 reference

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Cell contact-dependent activation of alpha3beta1 integrin modulates endothelial cell responses to thrombospondin-1

5 July 2018

1 reference

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5 July 2018

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Thrombospondin-1 is a major activator of TGF-beta1 in vivo

5 July 2018

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Elevated expression of transforming growth factor-beta in adipose tissue from obese mice

5 July 2018

1 reference

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Cellular internalization and degradation of thrombospondin-1 is mediated by the amino-terminal heparin binding domain (HBD). High affinity interaction of dimeric HBD with the low density lipoprotein receptor-related protein

5 July 2018

1 reference

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Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism

5 July 2018

1 reference

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A thrombin-sensitive protein of human platelet membranes

5 July 2018

1 reference

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Thrombospondin-induced tumor cell migration: haptotaxis and chemotaxis are mediated by different molecular domains

5 July 2018

1 reference

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Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors

5 July 2018

1 reference

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Interactions of thrombospondin with endothelial cells: receptor-mediated binding and degradation

5 July 2018

1 reference

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Thrombospondin gene expression is associated with mitogenesis in 3T3 cells: induction by basic fibroblast growth factor

5 July 2018

1 reference

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Isolation and characterization of a high molecular weight glycoprotein from human blood platelets

5 July 2018

1 reference

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Evaluating the glucose tolerance test in mice

5 July 2018

1 reference

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Among inflammation and coagulation markers, PAI-1 is a true component of the metabolic syndrome

28 October 2018

1 reference

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Molecular interactions that confer latency to transforming growth factor-beta

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200349

Carboxypeptidase E and thrombospondin-1 are differently expressed in subcutaneous and visceral fat of obese subjects.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200349

Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3200349

Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1

28 October 2018

1 reference

12 December 2020

Thrombospondin mediates focal adhesion disassembly through interactions with cell surface calreticulin

1 reference

12 December 2020

The type 1 repeats of thrombospondin 1 activate latent transforming growth factor-beta

1 reference

12 December 2020

Thrombospondin promotes chemotaxis and haptotaxis of human peripheral blood monocytes

1 reference

12 December 2020

Thrombospondin 1 is expressed by proliferating mesangial cells and is up-regulated by PDGF and bFGF in vivo

1 reference

12 December 2020

Hypoxia increases thrombospondin-1 transcript and protein in cultured endothelial cells

1 reference

12 December 2020

The thrombospondin receptor integrin-associated protein (CD47) functionally couples to heterotrimeric Gi

1 reference

12 December 2020

Deficiency of thrombospondin-1 in mice does not affect adipose tissue development

1 reference

12 December 2020

Inflammation and insulin resistance

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0026656

Identifiers

DOI

1 reference

release_r2gti7dgjvdmfa2davycwiwnka

30 July 2017

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Fatcat

https://api.fatcat.wiki/v0/release/r2gti7dgjvdmfa2davycwiwnka

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3200349

1 reference

30 July 2017

1 reference