Selecting optimal antisense reagents (Q34062626)

30 July 2017

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title

Selecting optimal antisense reagents (English)

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30 July 2017

Sohail M

1

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30 July 2017

Southern EM

series ordinal

2

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30 July 2017

language of work or name

English

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publication date

1 October 2000

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Advanced Drug Delivery Reviews

30 July 2017

published in

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30 July 2017

volume

44

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30 July 2017

issue

1

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30 July 2017

page(s)

23-34

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Selecting effective antisense reagents on combinatorial oligonucleotide arrays

30 July 2017

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Searching for the ideal partner

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Theoretical design of antisense RNA structures substantially improves annealing kinetics and efficacy in human cells

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Anti-sense phosphorothioate oligonucleotides have both specific and non-specific effects on cells containing human papillomavirus type 16

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Ending the message is not so simple

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Tetranucleotide GGGA motif in primary RNA transcripts. Novel target site for antisense design

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Bias in nucleotide composition of antisense oligonucleotides

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Target site selection for an RNA-cleaving catalytic DNA

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Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase

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A method for screening antisense oligodeoxyribonucleotides effective for mRNA translation-arrest

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Inhibition of human TNF alpha and LT in cell-free extracts and in cell culture by antisense oligonucleotides.

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In vitro efficacy of morpholino-modified antisense oligomers directed against tumor necrosis factor-alpha mRNA

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Core specific antisense phosphorothioate oligodeoxynucleotides as potent and specific inhibitors of hepatitis C viral translation

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On finding all suboptimal foldings of an RNA molecule

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Implication of RNA structure on antisense oligonucleotide hybridization kinetics

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Overcoming multidrug resistance in human tumor cells using free and liposomally encapsulated antisense oligodeoxynucleotides

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Specific inhibition of expression of a human collagen gene (COL1A1) with modified antisense oligonucleotides. The most effective target sites are clustered in double-stranded regions of the predicted secondary structure for the mRNA.

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Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis

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Molecular interactions on microarrays

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Three-Dimensional Tertiary Structure of Yeast Phenylalanine Transfer RNA

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Protein Enhancement of Hammerhead Ribozyme Catalysis

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7 January 2021

Site specific enzymatic cleavage of RNA

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7 January 2021

Specificity of antisense oligonucleotides in vivo

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Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping RNA-accessible sites with oligonucleotide libraries

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A DNA enzyme that cleaves RNA

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7 January 2021

A general purpose RNA-cleaving DNA enzyme

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7 January 2021

Construction of a directed hammerhead ribozyme library: towards the identification of optimal target sites for antisense-mediated gene inhibition

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Mapping adenines, guanines, and pyrimidines in RNA

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7 January 2021

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Identifiers

DOI

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30 July 2017

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