Regulation of metallothionein gene expression (Q34070583)

30 July 2017

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title

Regulation of metallothionein gene expression. (English)

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30 July 2017

Ghoshal K

1

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30 July 2017

Jacob ST

series ordinal

2

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30 July 2017

publication date

1 January 2001

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Progress in Molecular Biology and Translational Science

30 July 2017

published in

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30 July 2017

volume

66

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30 July 2017

page(s)

357-384

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A CADMIUM PROTEIN FROM EQUINE KIDNEY CORTEX

30 July 2017

cites work

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CTG Triplet Repeat in Mouse Growth Inhibitory Factor/Metallothionein III Gene Promoter Represses the Transcriptional Activity of the Heterologous Promoters

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Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia

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Expression of the gene encoding metallothionein-3 in organs of the reproductive system

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7 January 2021

Bioactivity of Metallothionein-3 Correlates with Its Novel .beta. Domain Sequence Rather Than Metal Binding Properties

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2 Definitions and nomenclature of metallothioneins

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Metallothionein in physiological and physiopathological processes

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Biological significance of non-acetylated metallothionein

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59 Determination of the three-dimensional structure of metallothioneins by nuclear magnetic resonance spectroscopy in solution

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69 Overview of metallothionein

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Thionein (apometallothionein) can modulate DNA binding and transcription activation by zinc finger containing factor Sp1.

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A murine model of Menkes disease reveals a physiological function of metallothionein

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Yeast and mammalian metallothioneins functionally substitute for yeast copper-zinc superoxide dismutase

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Deletion in human chromosome region 12q13-15 by integration of human papillomavirus DNA in a cervical carcinoma cell line.

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Overexpression of metallothionein in the heart of transgenic mice suppresses doxorubicin cardiotoxicity

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Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases

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7 January 2021

Liver metallothionein expression in thioacetamide-intoxicated rats

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7 January 2021

Transcriptional induction of metallothionein-I and -II genes in the livers of Cu,Zn-superoxide dismutase knockout mice.

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The nature of antioxidant defense mechanisms: a lesson from transgenic studies

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The significance of the nuclear and cytoplasmic localization of metallothionein in human liver and tumor cells

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Nuclear import of metallothionein requires its mRNA to be associated with the perinuclear cytoskeleton

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7 January 2021

Metallothionein overexpression suppresses hepatic hyperplasia induced by hepatitis B surface antigen

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Metallothioneins in brain--the role in physiology and pathology.

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7 January 2021

Disruption of the metallothionein-III gene in mice: analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures.

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7 January 2021

Constitutive expression of metallothionein-III (MT-III), but not MT-I, inhibits growth when cells become zinc deficient

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7 January 2021

Ectopic expression of metallothionein-III causes pancreatic acinar cell necrosis in transgenic mice

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7 January 2021

Metallothioneins: proteins in search of function

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7 January 2021

Molecular analyses of metallothionein gene regulation.

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7 January 2021

Metal-regulated transcription in eukaryotes

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7 January 2021

Antioxidant response element

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7 January 2021

Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements

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7 January 2021

Participation of upstream stimulator factor (USF) in cadmium-induction of the mouse metallothionein-I gene

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7 January 2021

Purification and characterization of a rat liver protein that recognizes CCAAT-homologous sequences of the metallothionein promoter and trans-activates this promoter

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7 January 2021

Distinct rat proteins can recognize CCAAT-homologous sequences of the metallothionein promoter and trans-activate this promoter

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7 January 2021

Roles of the NFI/CTF gene family in transcription and development

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7 January 2021

Constitutive and metal-inducible protein:DNA interactions at the mouse metallothionein I promoter examined by in vivo and in vitro footprinting

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7 January 2021

Oxidative stress activates metal-responsive transcription factor-1 binding activity. Occupancy in vivo of metal response elements in the metallothionein-I gene promoter

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7 January 2021

Hypermethylation of metallothionein-I promoter and suppression of its induction in cell lines overexpressing the large subunit of Ku protein

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7 January 2021

Suppression of metallothionein gene expression in a rat hepatoma because of promoter-specific DNA methylation

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7 January 2021

The DNA binding activity of metal response element-binding transcription factor-1 is activated in vivo and in vitro by zinc, but not by other transition metals

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7 January 2021

Cloned transcription factor MTF-1 activates the mouse metallothionein I promoter.

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7 January 2021

Purification of mouse MEP-1, a nuclear protein which binds to the metal regulatory elements of genes encoding metallothionein

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7 January 2021

Interactions of the zinc-regulated factor (ZiRF1) with the mouse metallothionein Ia promoter

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7 January 2021

Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1

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7 January 2021

Functional domains of the heavy metal-responsive transcription regulator MTF-1.

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7 January 2021

Analysis of the heavy metal-responsive transcription factor MTF-1 from human and mouse

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7 January 2021

Zinc and cadmium can promote rapid nuclear translocation of metal response element-binding transcription factor-1

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7 January 2021

Metal-induced metallothionein gene expression can be inactivated by protein kinase C inhibitor

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7 January 2021

Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.

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7 January 2021

Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc

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7 January 2021

Oxidative mechanisms in the toxicity of metal ions

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7 January 2021

Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes

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7 January 2021

Regulation of metallothionein gene expression by oxidative stress and metal ions

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7 January 2021

Transcriptional regulation of mouse liver metallothionein-I gene by glucocorticoids

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7 January 2021

Metallothionein mRNA induction in HeLa cells in response to zinc or dexamethasone is a primary induction response

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7 January 2021

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

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7 January 2021

Nuclear receptors: coactivators, corepressors and chromatin remodeling in the control of transcription

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7 January 2021

Steroid and nuclear receptors. Villefranche-sur-Mer, France, May 25-27, 1999.

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7 January 2021

Metallothionein induction in response to restraint stress. Transcriptional control, adaptation to stress, and role of glucocorticoid

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7 January 2021

METALLOTHIONEIN INDUCTION BY RESTRAINT STRESS: ROLE OF GLUCOCORTICOIDS AND IL-6

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7 January 2021

Blocking effect of anti-mouse interleukin-6 monoclonal antibody and glucocorticoid receptor antagonist, RU38486, on metallothionein-inducing activity of serum from lipopolysaccharide-treated mice

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7 January 2021

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

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7 January 2021

Identification of a signal transducer and activator of transcription (STAT) binding site in the mouse metallothionein-I promoter involved in interleukin-6-induced gene expression

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7 January 2021

Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic mice

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7 January 2021

Sensitivity to cadmium-induced genotoxicity in rat testicular cells is associated with minimal expression of the metallothionein gene

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7 January 2021

Metallothionein gene expression in testicular interstitial cells and liver of rats treated with cadmium

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7 January 2021

Cadmium-induced apoptosis and changes in expression of p53, c-jun and MT-I genes in testes and ventral prostate of rats

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7 January 2021

Metallothionein genes MTa and MTb expressed under distinct quantitative and tissue-specific regulation in sea urchin embryos.

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7 January 2021

Metallothionein Mto gene of Drosophila melanogaster: structure and regulation

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7 January 2021

Expression of metallothionein genes during the post-embryonic development of Drosophila melanogaster.

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7 January 2021

Regulation of metallothionein gene transcription. Identification of upstream regulatory elements and transcription factors responsible for cell-specific expression of the metallothionein genes from Caenorhabditis elegans

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7 January 2021

trans repression of the human metallothionein IIA gene promoter by PZ120, a novel 120-kilodalton zinc finger protein

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7 January 2021

Replication protein A is a component of a complex that binds the human metallothionein IIA gene transcription start site

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7 January 2021

Abundance of hepatic metallothionein mRNA is increased by protein-synthesis inhibitors. Evidence for transcriptional activation and post-transcriptional regulation

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7 January 2021

Signalling and superinduction

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7 January 2021

S-phase-dependent action of cycloheximide in relieving chromatin-mediated general transcriptional repression

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7 January 2021

Butyrate selectively activates the metallothionein gene in teratocarcinoma cells and induces hypersensitivity to metal induction

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7 January 2021

Regulation of the rat metallothionein-I gene by sodium butyrate

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7 January 2021

Butyrate-induced changes in nuclease sensitivity of chromatin cannot be correlated with transcriptional activation

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7 January 2021

Scaffold-attached regions (SAR elements) mediate transcriptional effects due to butyrate

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7 January 2021

Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA.

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7 January 2021

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

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7 January 2021

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

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7 January 2021

Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation

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7 January 2021

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

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7 January 2021

Roles of histone acetyltransferases and deacetylases in gene regulation

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7 January 2021

Control of histone modifications

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7 January 2021

Alternative inducers of the rat metallothionein I gene cause distinct changes in chromatin structure in the 5' region of the gene

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7 January 2021

Looping versus linking: toward a model for long-distance gene activation

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7 January 2021

The mystique of epigenetics

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7 January 2021

Epigenetics: regulation through repression

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DNA methylation and imprinting: why bother?

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Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

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7 January 2021

Gene expression profiles in normal and cancer cells

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7 January 2021

Role of metallothionein in carcinogenesis

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7 January 2021

DNA methylation controls the inducibility of the mouse metallothionein-I gene in lymphoid cells

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7 January 2021

Ultraviolet radiation-induced metallothionein-I gene activation is associated with extensive DNA demethylation.

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7 January 2021

Effect of 5-azacytidine on metallothionein inducibility and sensitivity to lethality of cadmium in rat osteosarcoma (ROS 17/2.8) cells

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7 January 2021

Silencing of metallothionein-I gene in mouse lymphosarcoma cells by methylation

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7 January 2021

Methylation-induced repression--belts, braces, and chromatin

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7 January 2021

High sensitivity mapping of methylated cytosines

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7 January 2021

Differential sensitivity of zinc finger transcription factors MTF-1, Sp1 and Krox-20 to CpG methylation of their binding sites.

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7 January 2021

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

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7 January 2021

Cytosine methylation prevents binding to DNA of a HeLa cell transcription factor required for optimal expression of the adenovirus major late promoter

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7 January 2021

How does DNA methylation repress transcription?

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7 January 2021

Role of DNA 5-methylcytosine transferase in cell transformation by fos

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7 January 2021

A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

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7 January 2021

Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases

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7 January 2021

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

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7 January 2021

Downregulation of metallothionein-IIA expression occurs at immortalization

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7 January 2021

10.1016/S0079-6603(00)66034-8

Identifiers

DOI

1 reference

30 July 2017

1 reference