The genetic basis of kidney cancer: a metabolic disease (Q34087148)

30 July 2017

1 reference

title

The genetic basis of kidney cancer: a metabolic disease (English)

1 reference

30 July 2017

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1 reference

W Marston Linehan

1

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30 July 2017

Ramaprasad Srinivasan

series ordinal

2

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30 July 2017

Laura S Schmidt

series ordinal

3

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30 July 2017

language of work or name

English

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publication date

1 May 2010

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30 July 2017

published in

Nature Reviews Urology

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30 July 2017

volume

7

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30 July 2017

issue

5

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30 July 2017

page(s)

277-285

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Molecular diagnosis and therapy of kidney cancer

30 July 2017

cites work

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dubé syndrome: a new series of 50 families and a review of published reports

5 July 2018

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Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys

5 July 2018

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5 July 2018

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5 July 2018

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Lung cysts, spontaneous pneumothorax, and genetic associations in 89 families with Birt-Hogg-Dubé syndrome

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

5 July 2018

1 reference

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HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

5 July 2018

1 reference

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Novel mutations in FH and expansion of the spectrum of phenotypes expressed in families with hereditary leiomyomatosis and renal cell cancer

5 July 2018

1 reference

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Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dubé syndrome

5 July 2018

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5 July 2018

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma

5 July 2018

1 reference

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The genetic basis of cancer of the kidney

5 July 2018

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5 July 2018

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Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America

5 July 2018

1 reference

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

5 July 2018

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Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype

5 July 2018

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

5 July 2018

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5 July 2018

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Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

5 July 2018

1 reference

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The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

5 July 2018

1 reference

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Tuberous sclerosis-associated renal cell carcinoma. Clinical, pathological, and genetic features

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929006

Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein

5 July 2018

1 reference

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Identification of the von Hippel-Lindau disease tumor suppressor gene

5 July 2018

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Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas.

5 July 2018

1 reference

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Mutations of the VHL tumour suppressor gene in renal carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929006

Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929006

Inhibition of Transcription Elongation by the VHL Tumor Suppressor Protein

5 July 2018

1 reference

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Renal medullary carcinoma. The seventh sickle cell nephropathy

5 July 2018

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Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma

5 July 2018

1 reference

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Isolation and regional localization of a large collection (2,000) of single-copy DNA fragments on human chromosome 3 for mapping and cloning tumor suppressor genes

5 July 2018

1 reference

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5 July 2018

1 reference

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Molecular and genetic characterization and physical mapping of 11 new markers detecting multiallele restriction fragment length polymorphisms on the short arm of human chromosome 3

5 July 2018

1 reference

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Hereditary Multiple Fibrofolliculomas With Trichodiscomas and Acrochordons

5 July 2018

1 reference

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Attacking cancer at its root

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929006

Clinical manifestations of familial paraganglioma and phaeochromocytomas in succinate dehydrogenase B (SDH-B) gene mutation carriers

28 October 2018

1 reference

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High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors.

28 October 2018

1 reference

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In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship.

28 October 2018

1 reference

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Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.

28 October 2018

1 reference

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The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma

28 October 2018

1 reference

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Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929006

Improved detection of germline mutations in the von Hippel-Lindau disease tumor suppressor gene

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929006

Genetic linkage between von Hippel-Lindau disease and three microsatellite polymorphisms refines the localisation of the VHL locus

28 October 2018

1 reference

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Renal Tumors in the Birt-Hogg-Dubé Syndrome

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2010.47

Evaluation and management of renal tumors in the Birt-Hogg-Dubé syndrome

31 March 2020

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The morphologic spectrum of kidney tumors in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRUROL.2010.47

Renal epithelial neoplasms: the diagnostic implications of electron microscopic study in 55 cases

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRUROL.2010.47

Obesity, hypertension, and the risk of kidney cancer in men

31 March 2020

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Screening for von Hippel-Lindau disease by DNA polymorphism analysis

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20448661

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRUROL.2010.47

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference