The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function (Q34103308)

31 July 2017

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title

The ITAM-bearing transmembrane adaptor DAP12 in lymphoid and myeloid cell function (English)

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31 July 2017

main subject

transmembrane protein

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cell function

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author name string

L L Lanier

series ordinal

1

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31 July 2017

A B Bakker

series ordinal

2

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31 July 2017

publication date

1 December 2000

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31 July 2017

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31 July 2017

volume

21

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31 July 2017

issue

12

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31 July 2017

page(s)

611-614

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The Syk family of protein tyrosine kinases in T-cell activation and development

31 July 2017

cites work

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ITAM multiplicity and thymocyte selection: how low can you go?

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Regulation of immune responses through inhibitory receptors

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Existence of both inhibitory (p58) and activatory (p50) receptors for HLA-C molecules in human natural killer cells

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A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation

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Gene structure, expression pattern, and biological activity of mouse killer cell activating receptor-associated protein (KARAP)/DAP-12

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Signaling through human killer cell activating receptors triggers tyrosine phosphorylation of an associated protein complex

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7 January 2021

Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells

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Interaction of Ly-49D+ NK cells with H-2Dd target cells leads to Dap-12 phosphorylation and IFN-gamma secretion

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Induction of DAP12 phosphorylation, calcium mobilization, and cytokine secretion by Ly49H

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Association of DAP12 with activating CD94/NKG2C NK cell receptors

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NKp44, a novel triggering surface molecule specifically expressed by activated natural killer cells, is involved in non-major histocompatibility complex-restricted tumor cell lysis

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DAP12-mediated signal transduction in natural killer cells. A dominant role for the Syk protein-tyrosine kinase

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Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells

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Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes

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7 January 2021

Cutting edge: signal-regulatory protein beta 1 is a DAP12-associated activating receptor expressed in myeloid cells

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7 January 2021

Association of signal-regulatory proteins beta with KARAP/DAP-12

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High expression of inhibitory receptor SHPS-1 and its association with protein-tyrosine phosphatase SHP-1 in macrophages

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MFR, a putative receptor mediating the fusion of macrophages

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A family of proteins that inhibit signalling through tyrosine kinase receptors

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Role of CD47 as a marker of self on red blood cells

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Nasu-Hakola syndrome: polycystic lipomembranous osteodysplasia with sclerosing leucoencephalopathy and presenile dementia

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7 January 2021

Assignment of the locus for PLO-SL, a frontal-lobe dementia with bone cysts, to 19q13.

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7 January 2021

Loss-of-function mutations in TYROBP (DAP12) result in a presenile dementia with bone cysts.

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DAP12-deficient mice fail to develop autoimmunity due to impaired antigen priming

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Combined natural killer cell and dendritic cell functional deficiency in KARAP/DAP12 loss-of-function mutant mice.

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Identifiers

DOI

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31 July 2017

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