Combining structural genomics and enzymology: completing the picture in metabolic pathways and enzyme active sites (Q34103432)

31 July 2017

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title

Combining structural genomics and enzymology: completing the picture in metabolic pathways and enzyme active sites (English)

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31 July 2017

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Erlandsen H

1

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31 July 2017

Abola EE

series ordinal

2

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31 July 2017

Stevens RC

series ordinal

3

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31 July 2017

publication date

1 December 2000

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Current Opinion in Structural Biology

31 July 2017

published in

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31 July 2017

volume

10

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31 July 2017

issue

6

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31 July 2017

page(s)

719-730

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Class-directed structure determination: foundation for a protein structure initiative

31 July 2017

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Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria

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Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria

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Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution

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Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase

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Mutation to phenylalanine of tyrosine 371 in tyrosine hydroxylase increases the affinity for phenylalanine

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Reversing the substrate specificities of phenylalanine and tyrosine hydroxylase: aspartate 425 of tyrosine hydroxylase is essential for L-DOPA formation

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The 1.25 A crystal structure of sepiapterin reductase reveals its binding mode to pterins and brain neurotransmitters

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Tetrahydrobiopterin biosynthesis, regeneration and functions

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The active site base controls cofactor reactivity in Escherichia coli amine oxidase: x-ray crystallographic studies with mutational variants

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The first structure of an aldehyde dehydrogenase reveals novel interactions between NAD and the Rossmann fold

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The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography

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One motif--many different reactions

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Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences

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Refined 1.83 Å structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 m-ammonium sulphate

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Structure of the R65Q mutant of yeast 3-phosphoglycerate kinase complexed with Mg-AMP-PNP and 3-phospho-D-glycerate

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Polyanionic inhibitors of phosphoglycerate mutase: combined structural and biochemical analysis

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Structure of a phosphoglycerate mutase:3-phosphoglyceric acid complex at 1.7 A

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The allosteric regulation of pyruvate kinase by fructose-1,6-bisphosphate

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Catalytic mechanism of the quinoenzyme amine oxidase from Escherichia coli: exploring the reductive half-reaction

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Structural and biochemical investigations of the catalytic mechanism of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans

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X-ray structure of human class IV sigmasigma alcohol dehydrogenase. Structural basis for substrate specificity

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Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes

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Structural basis of autoregulation of phenylalanine hydroxylase

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10.1016/S0959-440X(00)00154-8

Identifiers

DOI

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31 July 2017

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