Disruption of CREB function in brain leads to neurodegeneration (Q34124865)

31 July 2017

title

Disruption of CREB function in brain leads to neurodegeneration (English)

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31 July 2017

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Thomas Lemberger

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Theo Mantamadiotis

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Theo Mantamadiotis

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Ana Martín-Villalba

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object named as

Ana Martin Villalba

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François Tronche

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31 July 2017

Susanne C Bleckmann

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Heidrun Kern

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Oliver Kretz

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Christoph Kellendonk

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Daniel Gau

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Josef Kapfhammer

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Christiane Otto

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Wolfgang Schmid

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Günther Schütz

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language of work or name

English

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publication date

22 April 2002

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31 July 2017

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31 July 2017

volume

31

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issue

1

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page(s)

47-54

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Apoptosis in neurodegenerative disorders

31 July 2017

cites work

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7 January 2021

CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals

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7 January 2021

Transcriptional regulation by the phosphorylation-dependent factor CREB

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7 January 2021

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7 January 2021

CREB and its associated proteins act as survival factors for human melanoma cells

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7 January 2021

Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons

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7 January 2021

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

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7 January 2021

CREB couples neurotrophin signals to survival messages

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7 January 2021

CREB is a regulatory target for the protein kinase Akt/PKB

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7 January 2021

Targeted mutation of the CREB gene: compensation within the CREB/ATF family of transcription factors.

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7 January 2021

Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein

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7 January 2021

Spermiogenesis deficiency and germ-cell apoptosis in CREM-mutant mice

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Severe impairment of spermatogenesis in mice lacking the CREM gene

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7 January 2021

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

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7 January 2021

Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

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7 January 2021

Induction of bcl-2 expression by phosphorylated CREB proteins during B-cell activation and rescue from apoptosis

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7 January 2021

Targeted inactivation of Hoxb8 affects survival of a spinal ganglion and causes aberrant limb reflexes

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7 January 2021

Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice

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7 January 2021

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

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7 January 2021

Motor abnormalities in weaver mutant mice

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7 January 2021

Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1.

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A one-hit model of cell death in inherited neuronal degenerations

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7 January 2021

Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

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7 January 2021

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

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7 January 2021

CREB-binding protein sequestration by expanded polyglutamine

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7 January 2021

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

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7 January 2021

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

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7 January 2021

Neuropathological classification of Huntington's disease

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7 January 2021

Activating transcription factor 1 and CREB are important for cell survival during early mouse development

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7 January 2021

PCR-based strategy for genotyping mice and ES cells harboring loxP sites

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7 January 2021

Control of memory formation through regulated expression of a CaMKII transgene

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7 January 2021

Inducible site-specific recombination in the brain

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7 January 2021

Genomic analysis using a yeast artificial chromosome library with mouse DNA inserts

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7 January 2021

Identifiers

DOI

10.1038/NG882

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31 July 2017

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