Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors (Q34126142)

31 July 2017

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title

Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors (English)

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G protein-coupled receptor

31 July 2017

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author name string

Pyne S

series ordinal

1

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31 July 2017

Pyne N

series ordinal

2

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31 July 2017

publication date

1 November 2000

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Pharmacology & Therapeutics

31 July 2017

published in

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31 July 2017

volume

88

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31 July 2017

issue

2

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31 July 2017

page(s)

115-131

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Formyl peptide receptor signaling in HL-60 cells through sphingosine kinase

31 July 2017

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes

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Structure-activity relationship of short-chain sphingoid bases as inhibitors of sphingosine kinase

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

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Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation

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7 January 2021

Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate.

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7 January 2021

The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways.

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7 January 2021

EDG6, a novel G-protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue

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Effects of sphingosine 1-phosphate on pacemaker activity in rabbit sino-atrial node cells

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Ceramide in apoptosis--does it really matter?

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Sphingosine-1-phosphate modulates growth and adhesion of ovarian cancer cells

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Induction of apoptosis by sphingosine-1-phosphate in human hepatoma cells is associated with enhanced expression of bax gene product

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7 January 2021

Characterization of a novel sphingosine 1-phosphate receptor, Edg-8

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7 January 2021

Activation and translocation of Rho (and ADP ribosylation factor) by insulin in rat adipocytes. Apparent involvement of phosphatidylinositol 3-kinase

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7 January 2021

Inhibition of chemotactic motility and trans-endothelial migration of human neutrophils by sphingosine 1-phosphate

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7 January 2021

Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber disease

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7 January 2021

Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras

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Molecular cloning and functional characterization of murine sphingosine kinase

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Comparison of intrinsic activities of the putative sphingosine 1-phosphate receptor subtypes to regulate several signaling pathways in their cDNA-transfected Chinese hamster ovary cells

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Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

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p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

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Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1

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7 January 2021

Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist

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7 January 2021

Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

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7 January 2021

Sphingosine 1-phosphate induces angiogenesis: its angiogenic action and signaling mechanism in human umbilical vein endothelial cells

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7 January 2021

Signalling sphingomyelinases: which, where, how and why?

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7 January 2021

A putative G-protein-coupled receptor, H218, is down-regulated during the retinoic acid-induced differentiation of F9 embryonal carcinoma cells

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7 January 2021

Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione

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7 January 2021

Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death

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7 January 2021

Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma

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7 January 2021

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Cloning and characterization of a putative G-protein coupled receptor potentially involved in development

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7 January 2021

Signal transduction of stress via ceramide

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7 January 2021

Receptor-mediated activation of phospholipase D by sphingosine 1-phosphate in skeletal muscle C2C12 cells. A role for protein kinase C

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7 January 2021

FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking

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7 January 2021

Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors

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7 January 2021

Bioactive lysophospholipids and their G protein-coupled receptors

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7 January 2021

EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibitio

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7 January 2021

EDG3 is a functional receptor specific for sphingosine 1-phosphate and sphingosylphosphorylcholine with signaling characteristics distinct from EDG1 and AGR16

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7 January 2021

Molecular cloning of a novel putative G protein-coupled receptor expressed in the cardiovascular system

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Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

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7 January 2021

Purification and characterization of rat kidney sphingosine kinase

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7 January 2021

Platelet-derived growth factor-induced activation of sphingosine kinase requires phosphorylation of the PDGF receptor tyrosine residue responsible for binding of PLCgamma

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7 January 2021

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

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7 January 2021

Sphingosine-1-phosphate activates phospholipase D in human airway epithelial cells via a G protein-coupled receptor

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7 January 2021

The role of ceramide in cell signaling

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7 January 2021

The balance between sphingosine and sphingosine-1-phosphate is decisive for mast cell activation after Fc epsilon receptor I triggering

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7 January 2021

The differential regulation of cyclic AMP by sphingomyelin-derived lipids and the modulation of sphingolipid-stimulated extracellular signal regulated kinase-2 in airway smooth muscle

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7 January 2021

Sphingomyelin-derived lipids differentially regulate the extracellular signal-regulated kinase 2 (ERK-2) and c-Jun N-terminal kinase (JNK) signal cascades in airway smooth muscle

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7 January 2021

Sphingosine 1-phosphate stimulation of the p42/p44 mitogen-activated protein kinase pathway in airway smooth muscle. Role of endothelial differentiation gene 1, c-Src tyrosine kinase and phosphoinositide 3-kinase

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7 January 2021

Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors

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7 January 2021

Evidence that lipoproteins are carriers of bioactive factors

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7 January 2021

Exogenous sphingosine 1-phosphate induces neurite retraction possibly through a cell surface receptor in PC12 cells

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7 January 2021

Downregulation of mRNA expression of Edg-3, a putative sphingosine 1-phosphate receptor coupled to Ca2+ signaling, during differentiation of HL-60 leukemia cells

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7 January 2021

Possible involvement of cell surface receptors in sphingosine 1-phosphate-induced activation of extracellular signal-regulated kinase in C6 glioma cells

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Sphingosine-1-phosphate mobilizes intracellular calcium and activates transcription factor NF-kappa B in U937 cells

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7 January 2021

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling

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7 January 2021

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits

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Distribution and properties of dihydrosphingosine-1-phosphate aldolase (sphinganine-1-phosphate alkanal-lyase).

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7 January 2021

Ceramidase and ceramide synthesis in human kidney and cerebellum. Description of a new alkaline ceramidase

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7 January 2021

Sphingosine 1-phosphate mobilizes sequestered calcium, activates calcium entry, and stimulates deoxyribonucleic acid synthesis in thyroid FRTL-5 cells

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7 January 2021

Dual actions of sphingosine-1-phosphate: extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival

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7 January 2021

Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218

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7 January 2021

Sphinganine 1-phosphate metabolism in cultured skin fibroblasts: evidence for the existence of a sphingosine phosphatase.

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7 January 2021

Sphingosine 1-phosphate stimulates rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts

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7 January 2021

Involvement of focal adhesion kinase in inhibition of motility of human breast cancer cells by sphingosine 1-phosphate

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7 January 2021

Sphingosine 1-phosphate stimulates cell migration through a G(i)-coupled cell surface receptor. Potential involvement in angiogenesis

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7 January 2021

Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins

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7 January 2021

Sphingosine 1-phosphate rapidly activates the mitogen-activated protein kinase pathway by a G protein-dependent mechanism

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7 January 2021

Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

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7 January 2021

High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL

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7 January 2021

Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells

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7 January 2021

Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway

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7 January 2021

Activation of protein-tyrosine kinase Syk in human platelets stimulated with lysophosphatidic acid or sphingosine 1-phosphate

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7 January 2021

Metabolism and functional effects of sphingolipids in blood cells

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7 January 2021

N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets

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7 January 2021

Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation

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7 January 2021

Identification of the first mammalian sphingosine phosphate lyase gene and its functional expression in yeast

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7 January 2021

Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1.

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7 January 2021

10.1016/S0163-7258(00)00084-X

Identifiers

DOI

1 reference

31 July 2017

1 reference