Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension. (Q34168724)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12388768%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

title

Mad2 and BubR1 function in a single checkpoint pathway that responds to a loss of tension (English)

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14 December 2019

1

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14 December 2019

author name string

Julie C Canman

series ordinal

2

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14 December 2019

E D Salmon

series ordinal

3

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14 December 2019

publication date

1 October 2002

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Molecular Biology of the Cell

14 December 2019

published in

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14 December 2019

volume

13

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14 December 2019

issue

10

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14 December 2019

page(s)

3706-3719

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Inducing precocious anaphase in cultured mammalian cells

14 December 2019

cites work

1 reference

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Spindle checkpoint requires Mad1-bound and Mad1-free Mad2.

5 July 2018

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Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex

5 July 2018

1 reference

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The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20

5 July 2018

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Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells

5 July 2018

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Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint

5 July 2018

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Mad2-Independent inhibition of APCCdc20 by the mitotic checkpoint protein BubR1.

5 July 2018

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Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

5 July 2018

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5 July 2018

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Spindle checkpoint protein Bub1 is required for kinetochore localization of Mad1, Mad2, Bub3, and CENP-E, independently of its kinase activity

5 July 2018

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Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints

5 July 2018

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Dynein is a transient kinetochore component whose binding is regulated by microtubule attachment, not tension

5 July 2018

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Visualization of Mad2 dynamics at kinetochores, along spindle fibers, and at spindle poles in living cells

5 July 2018

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Kinetochore "memory" of spindle checkpoint signaling in lysed mitotic cells

5 July 2018

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The role of pre- and post-anaphase microtubules in the cytokinesis phase of the cell cycle

5 July 2018

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The polarity and dynamics of microtubule assembly in the budding yeast Saccharomyces cerevisiae

5 July 2018

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The kinetochore of higher eucaryotes: a molecular view

5 July 2018

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Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC

5 July 2018

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Whose end is destruction: cell division and the anaphase-promoting complex

5 July 2018

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Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores

5 July 2018

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Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1

5 July 2018

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The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

5 July 2018

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The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

5 July 2018

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Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129977

Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129977

MAD2 associates with the cyclosome/anaphase-promoting complex and inhibits its activity

5 July 2018

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Kinetochore fiber maturation in PtK1 cells and its implications for the mechanisms of chromosome congression and anaphase onset

5 July 2018

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Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage

5 July 2018

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How proteolysis drives the cell cycle

5 July 2018

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Identification of a human mitotic checkpoint gene: hsMAD2

5 July 2018

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5 July 2018

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The force for poleward chromosome motion in Haemanthus cells acts along the length of the chromosome during metaphase but only at the kinetochore during anaphase

5 July 2018

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Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle

5 July 2018

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Mitotic forces control a cell-cycle checkpoint

5 July 2018

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5 July 2018

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Microinjection of mitotic cells with the 3F3/2 anti-phosphoepitope antibody delays the onset of anaphase

5 July 2018

1 reference

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Differential expression of a phosphoepitope at the kinetochores of moving chromosomes

5 July 2018

1 reference

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The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129977

Kinetochore chemistry is sensitive to tension and may link mitotic forces to a cell cycle checkpoint

5 July 2018

1 reference

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The attachment of kinetochores to the pro-metaphase spindle in PtK1 cells. Recovery from low temperature treatment

5 July 2018

1 reference

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Newt lung epithelial cells: cultivation, use, and advantages for biomedical research.

5 July 2018

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Chromosome fiber dynamics and congression oscillations in metaphase PtK2 cells at 23 degrees C.

5 July 2018

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Feedback control of mitosis in budding yeast

5 July 2018

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S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

5 July 2018

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Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpoint

5 July 2018

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Checkpoint signals in grasshopper meiosis are sensitive to microtubule attachment, but tension is still essential.

28 October 2018

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Lack of tension at kinetochores activates the spindle checkpoint in budding yeast

28 October 2018

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12 December 2020

Effect of hypothermia (20-25 degrees C) on mitosis in PtK1 cells

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12 December 2020

Microtubule dynamics in the chromosomal spindle fiber: analysis by fluorescence and high-resolution polarization microscopy

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Oscillating mitotic newt lung cell kinetochores are, on average, under tension and rarely push

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The spindle checkpoint

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12 December 2020

Identifiers

DOI

10.1091/MBC.E02-03-0137

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12388768%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

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14 December 2019

PubMed publication ID

12388768

1 reference