Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses. (Q34192331)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21670730%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

review article

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title

Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21670730%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21670730%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Michael Goddard

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21670730%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Eske M Derks

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21670730%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

Naomi R. Wray

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21670730%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

4

N R Wray

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31 July 2017

M E Goddard

2

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31 July 2017

E M Derks

3

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31 July 2017

language of work or name

English

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publication date

14 June 2011

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4 February 2020

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4 February 2020

volume

17

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4 February 2020

issue

5

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4 February 2020

page(s)

474-485

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21670730%20AND%20SRC:MED&resulttype=core&format=json

The surprisingly rich contours of schizophrenia epidemiology

4 February 2020

cites work

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A polygenic theory of schizophrenia

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Resolving genetic models for the transmission of schizophrenia.

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Narrowing the boundaries of the genetic architecture of schizophrenia.

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Sporadic cases are the norm for complex disease

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Exchangeable models of complex inherited diseases

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Multi-locus models of genetic risk of disease

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The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study

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Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies

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Onset of major depression in early adulthood. Increased familial loading and specificity.

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A hospital-based twin register of the heritability of DSM-IV unipolar depression

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The lifetime history of major depression in women. Reliability of diagnosis and heritability

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Reliability of a lifetime history of major depression: implications for heritability and co-morbidity

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Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

21 January 2018

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Twin studies of schizophrenia: from bow-and-arrow concordances to star wars Mx and functional genomics

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Reproductive patterns in psychotic patients.

21 January 2018

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The role of genetic variation in the causation of mental illness: an evolution-informed framework

21 January 2018

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Evolutionary Rate at the Molecular Level

21 January 2018

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Statistical properties of segregating sites

21 January 2018

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Evolution in health and medicine Sackler colloquium: Genetic architecture of a complex trait and its implications for fitness and genome-wide association studies

21 January 2018

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Schizophrenia: a common disease caused by multiple rare alleles

21 January 2018

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On the allelic spectrum of human disease

21 January 2018

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Genetics of psychosis; insights from views across the genome

21 January 2018

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The role of copy number variation in schizophrenia

21 January 2018

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Synthetic associations created by rare variants do not explain most GWAS results

21 January 2018

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Copy number variations and risk for schizophrenia in 22q11.2 deletion syndrome

21 January 2018

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Chromosome 22-specific low copy repeats and the 22q11.2 deletion syndrome: genomic organization and deletion endpoint analysis

21 January 2018

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Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits

21 January 2018

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Finding the missing heritability of complex diseases

21 January 2018

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Common SNPs explain a large proportion of the heritability for human height

21 January 2018

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Estimating Effects and Making Predictions from Genome-Wide Marker Data

21 January 2018

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A commentary on 'common SNPs explain a large proportion of the heritability for human height' by Yang et al. (2010).

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.65

Hundreds of variants clustered in genomic loci and biological pathways affect human height

21 January 2018

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Support for the involvement of large copy number variants in the pathogenesis of schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.65

Strong association of de novo copy number mutations with sporadic schizophrenia

21 January 2018

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Rare chromosomal deletions and duplications increase risk of schizophrenia

21 January 2018

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Large recurrent microdeletions associated with schizophrenia

21 January 2018

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Analyze multivariate phenotypes in genetic association studies by combining univariate association tests

21 January 2018

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Not really identical: epigenetic differences in monozygotic twins and implications for twin studies in psychiatry.

21 January 2018

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Genetic or epigenetic difference causing discordance between monozygotic twins as a clue to molecular basis of mental disorders

21 January 2018

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Estimating missing heritability for disease from genome-wide association studies

21 January 2018

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Prediction of individual genetic risk to disease from genome-wide association studies

21 January 2018

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Genome-wide association study of recurrent major depressive disorder in two European case–control cohorts

21 January 2018

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Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

21 January 2018

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Genome-wide association study of recurrent early-onset major depressive disorder

21 January 2018

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Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies

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Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression

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Genome-wide association study identifies novel breast cancer susceptibility loci

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Rethinking the genetic architecture of schizophrenia.

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Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories?

21 January 2018

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Familiality of symptom dimensions in depression.

21 January 2018

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Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

21 January 2018

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21 January 2018

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Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk

21 January 2018

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The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia

21 January 2018

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The beginning of the end for the Kraepelinian dichotomy.

21 January 2018

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Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype

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The use of multiple thresholds in determining the mode of transmission of semi-continuous traits.

21 January 2018

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Data and theory point to mainly additive genetic variance for complex traits

21 January 2018

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Identification of loci associated with schizophrenia by genome-wide association and follow-up

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.65

Genome-wide association identifies a common variant in the reelin gene that increases the risk of schizophrenia only in women

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.65

Neurexin 1 (NRXN1) deletions in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.65

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.65

Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.65

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMP.2011.65

A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.65

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

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Phenotypic and genetic complexity of psychosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.65

Heritability of liability and concordance in monozygous twins

21 January 2018

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https://api.crossref.org/works/10.1038%2FMP.2011.65

7 January 2021

Multivariate stabilizing selection and pleiotropy in the maintenance of quantitative genetic variation

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7 January 2021

The new genomics: global views of biology

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https://api.crossref.org/works/10.1038%2FMP.2011.65

7 January 2021

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

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https://api.crossref.org/works/10.1038%2FMP.2011.65

7 January 2021

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

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https://api.crossref.org/works/10.1038%2FMP.2011.65

7 January 2021

Common variants on chromosome 6p22.1 are associated with schizophrenia

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7 January 2021

Common variants conferring risk of schizophrenia

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7 January 2021

Identifiers

DOI

10.1038/MP.2011.65

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21670730%20AND%20SRC:MED&resulttype=core&format=json

4 February 2020

1 reference