Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease (Q34214842)

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English	Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Beta-synuclein displays an antiapoptotic p53-dependent phenotype and protects neurons from 6-hydroxydopamine-induced caspase 3 activation: cross-talk with alpha-synuclein and implication for Parkinson's disease (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

Parkinson's disease

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Eliezer Masliah

2

object named as

Eliezer Masliah

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Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Cristine Alves da Costa

1

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31 July 2017

Frédéric Checler

3

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31 July 2017

language of work or name

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publication date

16 July 2003

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31 July 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

31 July 2017

278

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Europe PubMed Central

PubMed publication ID

31 July 2017

39

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Europe PubMed Central

PubMed publication ID

31 July 2017

37330-37335

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

1 reference

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Alpha-synuclein in Lewy bodies

1 reference

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Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

1 reference

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NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease

1 reference

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Alpha-synuclein in Lewy body disease and Alzheimer's disease

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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Polyglutamine expansions: proteolysis, chaperones, and the dangers of promiscuity

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Mechanisms of neurodegenerative disorders: Part 1: protein aggregates.

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Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

1 reference

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Wild-type but not Parkinson's disease-related ala-53 --> Thr mutant alpha -synuclein protects neuronal cells from apoptotic stimuli

1 reference

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21 January 2018

Alpha-synuclein lowers p53-dependent apoptotic response of neuronal cells. Abolishment by 6-hydroxydopamine and implication for Parkinson's disease

1 reference

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beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

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A Drosophila model of Parkinson's disease

1 reference

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Identification of two distinct synucleins from human brain

1 reference

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21 January 2018

Residues in the synuclein consensus motif of the α-synuclein fragment, NAC, participate in transglutaminase-catalysed cross-linking to Alzheimer-disease amyloid βA4 peptide

1 reference

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21 January 2018

Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease

1 reference

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Parkinson's disease-associated alpha-synuclein is more fibrillogenic than beta- and gamma-synuclein and cannot cross-seed its homologs

1 reference

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21 January 2018

Development of a new treatment for Alzheimer's disease and Parkinson's disease using anti-aggregatory beta-synuclein-derived peptides

1 reference

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21 January 2018

Clonal cell lines produced by infection of neocortical neuroblasts using multiple oncogenes transduced by retroviruses

1 reference

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Alpha-synuclein and the Parkinson's disease-related mutant Ala53Thr-alpha-synuclein do not undergo proteasomal degradation in HEK293 and neuronal cells

1 reference

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Cellular prion protein sensitizes neurons to apoptotic stimuli through Mdm2-regulated and p53-dependent caspase 3-like activation

1 reference

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21 January 2018

Definition of a consensus binding site for p53

1 reference

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p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons

1 reference

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Recent advances on alpha-synuclein cell biology: functions and dysfunctions.

1 reference

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The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

1 reference

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21 January 2018

Properties of NACP/alpha-synuclein and its role in Alzheimer's disease

1 reference

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21 January 2018

Alpha-synuclein and neurodegenerative diseases

1 reference

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21 January 2018

Non-A.beta. Component of Alzheimer's Disease Amyloid (NAC) is Amyloidogenic

1 reference

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Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

1 reference

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Review: formation and properties of amyloid-like fibrils derived from alpha-synuclein and related proteins

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Molecular mechanisms of selective dopaminergic neuronal death in Parkinson's disease

1 reference

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21 January 2018

Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306083200

21 January 2018

The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart

1 reference

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21 January 2018

A potential role for apoptosis in neurodegeneration and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306083200

21 January 2018

Apoptosis decision cascades and neuronal degeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306083200

21 January 2018

p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism

1 reference

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M306083200

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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