Caretaker or undertaker? The role of the proteasome in aging (Q34224564)

31 July 2017

1 reference

title

Caretaker or undertaker? The role of the proteasome in aging (English)

1 reference

31 July 2017

Gaczynska M

1

1 reference

31 July 2017

Osmulski PA

series ordinal

2

1 reference

31 July 2017

Ward WF

series ordinal

3

1 reference

31 July 2017

publication date

1 March 2001

1 reference

Mechanisms of Ageing and Development

31 July 2017

published in

1 reference

31 July 2017

volume

122

1 reference

31 July 2017

issue

3

1 reference

31 July 2017

page(s)

235-254

1 reference

Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Proteasome-mediated proteolysis of estrogen receptor: a novel component in autologous down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Proteolytic cleavage of N-Succ-Leu-Leu-Val-Tyr-AMC by the proteasome in lens epithelium from clear and cataractous human lenses

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Dietary self-selection can compensate an age-related decrease of rat liver 20 S proteasome activity observed with standard diet

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Identification of the yeast 20S proteasome catalytic centers and subunit interactions required for active-site formation

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Eukaryotic 20S proteasome catalytic subunit propeptides prevent active site inactivation by N-terminal acetylation and promote particle assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Changes in 20S proteasome activity during ageing of the LOU rat

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

1 reference

7 January 2021

Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

The base of the proteasome regulatory particle exhibits chaperone-like activity

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

ER protein quality control and proteasome-mediated protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

HEC binds to the seventh regulatory subunit of the 26 S proteasome and modulates the proteolysis of mitotic cyclins

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Proteasome inactivation upon aging and on oxidation-effect of HSP 90

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Structure and functions of the 20S and 26S proteasomes

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

The proteasome, a novel protease regulated by multiple mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Programmed cell death and the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Multiubiquitin chain binding and protein degradation are mediated by distinct domains within the 26 S proteasome subunit Mcb1.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Gamma-interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Proteasome subunits X and Y alter peptidase activities in opposite ways to the interferon-gamma-induced subunits LMP2 and LMP7.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

A giant protease with potential to substitute for some functions of the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Functional analysis of the proteasome regulatory particle

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Functions of the proteasome in antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Regulation of cell proliferation by the E2F transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Simultaneous binding of PA28 and PA700 activators to 20 S proteasomes

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

1 reference

7 January 2021

Ubiquitin-dependent protein degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Ubiquitin and ubiquitin conjugates in human lens

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Aging and cellular maturation cause changes in ubiquitin-eye lens protein conjugates

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Possible involvement of proteasome inhibition in aging: implications for oxidative stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

How proteolysis drives the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Proteasome inhibitors: valuable new tools for cell biologists

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Gene expression profile of aging and its retardation by caloric restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

The ubiquitin pathway in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Mitotic misregulation and human aging

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Nutrition and aging--a current assessment

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Effects of calorie restriction and aging on the expression of antioxidant enzymes and ubiquitin in the liver of Emory mice

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Evidence for the presence of five distinct proteolytic components in the pituitary multicatalytic proteinase complex. Properties of two components cleaving bonds on the carboxyl side of branched chain and small neutral amino acids

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Atomic force microscopy reveals two conformations of the 20 S proteasome from fission yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Lactacystin, a specific inhibitor of the proteasome, inhibits human platelet lysosomal cathepsin A-like enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Ubiquitin pools, ubiquitin mRNA levels, and ubiquitin-mediated proteolysis in aging human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Decreased proteasome-mediated degradation in T cells from the elderly: A role in immune senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Impaired immunoproteasome assembly and immune responses in PA28-/- mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Degradation of cell proteins and the generation of MHC class I-presented peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Inhibitory effect of p21 in MCF-7 cells is overcome by its coordinated stabilization with D-type cyclins

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Aging, calorie restriction and ubiquitin-dependent proteolysis in the livers of Emory mice

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Calorie restriction, stress and the ubiquitin-dependent pathway in mouse livers

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Alteration of rat liver 20S proteasome activities by age and food restriction.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Total synthesis of the potent proteasome inhibitor epoxomicin: a useful tool for understanding proteasome biology.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Differential gene expression in male and female rat lenses undergoing cataract induction by transforming growth factor-beta (TGF-beta).

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Hybrid proteasomes. Induction by interferon-gamma and contribution to ATP-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Proteasomes: structure and biology

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Tumour progression and angiogenesis in bone metastasis from breast cancer: new approaches to an old problem

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Altered peptidase and viral-specific T cell response in LMP2 mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

The 26S proteasome: a molecular machine designed for controlled proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

The Saccharomyces cerevisiae DNA repair gene RAD23 encodes a nuclear protein containing a ubiquitin-like domain required for biological function

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Food Restriction Enhances the Proteolytic Capacity of the Aging Rat Liver

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

Role of Proteasomes in Antigen Presentation

1 reference

https://api.crossref.org/works/10.1016%2FS0047-6374%2800%2900246-3

7 January 2021

10.1016/S0047-6374(00)00246-3

Identifiers

DOI

1 reference

31 July 2017

1 reference