International Myeloma Working Group molecular classification of multiple myeloma: spotlight review. (Q34241661)

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8 February 2020

review article

1 reference

title

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review (English)

1 reference

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8 February 2020

1 reference

1

1 reference

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8 February 2020

Norma C. Gutiérrez

5

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8 February 2020

Gareth J. Morgan

7

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8 February 2020

Antonino Neri

11

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8 February 2020

Herve Avet-Loiseau

22

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8 February 2020

S Minvielle

10

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Faith E Davies

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F Davies

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Brian Durie

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B G M Durie

1 reference

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8 February 2020

author name string

P L Bergsagel

2

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8 February 2020

J Drach

3

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8 February 2020

J Shaughnessy

4

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8 February 2020

A K Stewart

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8 February 2020

B Van Ness

8

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8 February 2020

M Chesi

9

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8 February 2020

B Barlogie

12

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8 February 2020

W M Kuehl

13

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8 February 2020

P Liebisch

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8 February 2020

S Chen-Kiang

16

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8 February 2020

R Carrasco

18

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8 February 2020

Orhan Sezer

19

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8 February 2020

Tony Reiman

20

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8 February 2020

Linda Pilarski

21

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8 February 2020

International Myeloma Working Group

23

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8 February 2020

publication date

1 October 2009

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8 February 2020

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8 February 2020

volume

23

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8 February 2020

issue

12

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8 February 2020

page(s)

2210-2221

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Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma

8 February 2020

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An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma

6 July 2018

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Myeloma in patients younger than age 50 years presents with more favorable features and shows better survival: an analysis of 10 549 patients from the International Myeloma Working Group

6 July 2018

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Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

6 July 2018

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Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer

6 July 2018

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6q deletion discriminates Waldenström macroglobulinemia from IgM monoclonal gammopathy of undetermined significance

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The molecular classification of multiple myeloma

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Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transpla

6 July 2018

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Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma.

6 July 2018

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Clinical implications of t(11;14)(q13;q32), t(4;14)(p16.3;q32), and -17p13 in myeloma patients treated with high-dose therapy

6 July 2018

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A validated FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS.

6 July 2018

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Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma

6 July 2018

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6 July 2018

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Possible roles for activating RAS mutations in the MGUS to MM transition and in the intramedullary to extramedullary transition in some plasma cell tumors

6 July 2018

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Inhibition of fibroblast growth factor receptor 3 induces differentiation and apoptosis in t(4;14) myeloma.

6 July 2018

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6 July 2018

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Deletions of chromosome 13 in multiple myeloma identified by interphase FISH usually denote large deletions of the q arm or monosomy.

6 July 2018

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Deletion of 13q14 remains an independent adverse prognostic variable in multiple myeloma despite its frequent detection by interphase fluorescence in situ hybridization

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28 October 2018

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28 October 2018

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28 October 2018

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Ploidy status rarely changes in myeloma patients at disease progression.

28 October 2018

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p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation

28 October 2018

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The t(4;14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant

28 October 2018

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Methylation of p16 and p15 genes in multiple myeloma.

28 October 2018

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Clinical and biologic implications of recurrent genomic aberrations in myeloma

28 October 2018

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Myeloma and the t(11;14)(q13;q32); evidence for a biologically defined unique subset of patients.

28 October 2018

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Monosomy 13 is associated with the transition of monoclonal gammopathy of undetermined significance to multiple myeloma. Intergroupe Francophone du Myélome.

28 October 2018

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Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy.

28 October 2018

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Molecular Dissection of Hyperdiploid Multiple Myeloma by Gene Expression Profiling

28 October 2018

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Prognostic value of chromosome 1q21 gain by fluorescent in situ hybridization and increase CKS1B expression in myeloma

28 October 2018

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High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients

28 October 2018

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The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma

28 October 2018

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Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma

28 October 2018

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High incidence of N and K-Ras activating mutations in multiple myeloma and primary plasma cell leukemia at diagnosis

28 October 2018

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The (11;14)(q13;q32) Translocation in Multiple Myeloma

28 October 2018

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Activating mutations of N- and K-ras in multiple myeloma show different clinical associations: analysis of the Eastern Cooperative Oncology Group Phase III Trial

9 December 2018

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12 December 2020

Unique role of cytogenetics in the prognosis of patients with myeloma receiving high-dose therapy and autotransplants

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12 December 2020

A novel three-color, clone-specific fluorescence in situ hybridization procedure for monoclonal gammopathies

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12 December 2020

Jumping translocations of chromosome 1q in multiple myeloma: evidence for a mechanism involving decondensation of pericentromeric heterochromatin

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12 December 2020

Prognostic value of numerical chromosome aberrations in multiple myeloma: A FISH analysis of 15 different chromosomes

1 reference

12 December 2020

Chromosomal analysis in multiple myeloma: cytogenetic evidence of two different diseases

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12 December 2020

Characterization of p16(INK4A) expression in multiple myeloma and plasma cell leukemia

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12 December 2020

14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process for the oncogenesis of multiple myeloma. Intergroupe Francophone du Myélome

1 reference

12 December 2020

Genetic risk identifies multiple myeloma patients who do not benefit from autologous stem cell transplantation

1 reference

12 December 2020

Hyperdiploidy is a common finding in monoclonal gammopathy of undetermined significance and monosomy 13 is restricted to these hyperdiploid patients

1 reference

12 December 2020

Gene mapping and expression analysis of 16q loss of heterozygosity identifies WWOX and CYLD as being important in determining clinical outcome in multiple myeloma

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12 December 2020

Multicolour spectral karyotyping identifies new translocations and a recurring pathway for chromosome loss in multiple myeloma

1 reference

12 December 2020

Chromosome 13 abnormalities in multiple myeloma are mostly monosomy 13

1 reference

12 December 2020

Hypermethylation of p16INK4A gene promoter during the progression of plasma cell dyscrasia

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12 December 2020

The t(4;14)(p16.3;q32) is strongly associated with chromosome 13 abnormalities in both multiple myeloma and monoclonal gammopathy of undetermined significance

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12 December 2020

Translocations involving the immunoglobulin heavy-chain locus are possible early genetic events in patients with primary systemic amyloidosis

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12 December 2020

Biological and prognostic significance of interphase fluorescence in situ hybridization detection of chromosome 13 abnormalities (delta13) in multiple myeloma: an eastern cooperative oncology group study

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12 December 2020

Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation

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12 December 2020

Translocations of 14q32 and deletions of 13q14 are common chromosomal abnormalities in systemic amyloidosis

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12 December 2020

Genomic abnormalities in monoclonal gammopathy of undetermined significance

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12 December 2020

Methylation is an inactivating mechanism of the p16 gene in multiple myeloma associated with high plasma cell proliferation and short survival

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12 December 2020

Translocation t(11;14)(q13;q32) is the hallmark of IgM, IgE, and nonsecretory multiple myeloma variants

1 reference

12 December 2020

In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression

1 reference

12 December 2020

Different prognostic values of p15(INK4b) and p16(INK4a) gene methylations in multiple myeloma

1 reference

12 December 2020

Integration of global SNP-based mapping and expression arrays reveals key regions, mechanisms, and genes important in the pathogenesis of multiple myeloma

1 reference

12 December 2020

Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma

1 reference

12 December 2020

Bortezomib plus melphalan and prednisone in elderly untreated patients with multiple myeloma: results of a multicenter phase 1/2 study

1 reference

12 December 2020

The association of increased p14ARF/p16INK4a and p15INK4a gene expression with proliferative activity and the clinical course of multiple myeloma

1 reference

12 December 2020

Prognostic and biological implications of genetic abnormalities in multiple myeloma undergoing autologous stem cell transplantation: t(4;14) is the most relevant adverse prognostic factor, whereas RB deletion as a unique abnormality is not associated

1 reference

12 December 2020

Bortezomib appears to overcome the poor prognosis conferred by chromosome 13 deletion in phase 2 and 3 trials

1 reference

12 December 2020

t(11;14) and t(4;14) translocations correlated with mature lymphoplasmacytoid and immature morphology, respectively, in multiple myeloma

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12 December 2020

Multiple myeloma involving central nervous system: high frequency of chromosome 17p13.1 (p53) deletions

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12 December 2020

Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities

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12 December 2020

Prognostic significance of copy-number alterations in multiple myeloma

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FLEU.2009.174

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/LEU.2009.174

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19798094%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

8 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19798094%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

19798094

1 reference