Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP (Q34258188)

31 July 2017

title

Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP (English)

1 reference

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24 September 2022

author name string

A. A. Hyman

1

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24 September 2022

S. Salser

2

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24 September 2022

D. N. Drechsel

3

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24 September 2022

N. Unwin

4

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24 September 2022

T. J. Mitchison

5

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24 September 2022

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1421572

24 September 2022

publication date

1 October 1992

1 reference

full work available at URL

31 July 2017

https://europepmc.org/articles/PMC275679

1 reference

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https://europepmc.org/articles/PMC275679?pdf=render

24 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1421572

Molecular Biology of the Cell

24 September 2022

published in

1 reference

31 July 2017

volume

3

1 reference

31 July 2017

issue

10

1 reference

31 July 2017

page(s)

1155-1167

1 reference

Cells injected with guanosine 5'-[alpha, beta-methylene]triphosphate, an alpha, beta-nonhydrolyzable analog of GTP, show anomalous patterns of tubulin polymerization affecting cell translocation, intracellular movement, and the organization of Golgi

31 July 2017

cites work

1 reference

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Dynamic instability of microtubule growth

6 July 2018

1 reference

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Microtubule assembly: a review of progress, principles, and perspectives.

6 July 2018

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Monte Carlo study of the GTP cap in a five-start helix model of a microtubule

6 July 2018

1 reference

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Beyond self-assembly: from microtubules to morphogenesis

6 July 2018

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Polewards chromosome movement driven by microtubule depolymerization in vitro

6 July 2018

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Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequencies

6 July 2018

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Direct incorporation of guanosine 5'-diphosphate into microtubules without guanosine 5'-triphosphate hydrolysis

6 July 2018

1 reference

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Direct observation of steady-state microtubule dynamics

6 July 2018

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Role of nucleotide hydrolysis in the dynamics of actin filaments and microtubules

6 July 2018

1 reference

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The structure of microtubule ends during the elongation and shortening phases of dynamic instability examined by negative-stain electron microscopy

6 July 2018

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Role of GTP hydrolysis in microtubule polymerization: evidence for a coupled hydrolysis mechanism

6 July 2018

1 reference

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Modulation of microtubule stability by kinetochores in vitro

6 July 2018

1 reference

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Dilution of individual microtubules observed in real time in vitro: evidence that cap size is small and independent of elongation rate

6 July 2018

1 reference

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Preparation of modified tubulins

6 July 2018

1 reference

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Microtubule dynamics and microtubule caps: a time-resolved cryo-electron microscopy study

6 July 2018

1 reference

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Preparation of marked microtubules for the assay of the polarity of microtubule-based motors by fluorescence

6 July 2018

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Microtubule dynamics: mechanism, regulation, and function.

6 July 2018

1 reference

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Gamma-tubulin is a centrosomal protein required for cell cycle-dependent microtubule nucleation

6 July 2018

1 reference

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Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau

6 July 2018

1 reference

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Tubulin-nucleotide interactions during the polymerization and depolymerization of microtubules

6 July 2018

1 reference

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Examination of tubulin-nucleotide interactions by protein fluorescence quenching measurements

6 July 2018

1 reference

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Nucleotide specificity in microtubule assembly in vitro

6 July 2018

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Microtubule Assembly and Nucleation

6 July 2018

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Role of nucleotides in tubulin polymerization: effect of guanosine 5'-methylene diphosphonate

6 July 2018

1 reference

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Nucleotide binding and phosphorylation in microtubule assembly in vitro

6 July 2018

1 reference

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Role of nucleotides in tubulin polymerization: effect of guanylyl 5'-methylenediphosphonate

6 July 2018

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Effect of guanine nucleotides on the assembly of brain microtubules: Ability of 5′-guanylyl imidodiphosphate to replace GTP in promoting the polymerization of microtubules in vitro

6 July 2018

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6 July 2018

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Interactions of tubulin with guanylyl-(beta-gamma-methylene)diphosphonate. Formation and assembly of a stoichiometric complex

6 July 2018

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Buffer conditions and non-tubulin factors critically affect the microtubule dynamic instability of sea urchin egg tubulin

28 October 2018

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GTP analogues interact with the tubulin exchangeable site during assembly and upon binding

28 October 2018

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12 December 2020

Kinetic analysis of guanosine 5'-triphosphate hydrolysis associated with tubulin polymerization

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12 December 2020

PHOSPHONIC ACID ANALOGS OF NUCLEOSIDE PHOSPHATES. 3. THE SYNTHESIS OF ADENOSINE-5'-METHYLENEDIPHOSPHONATE, A PHOSPHONIC ACID ANALOG OF ADENOSINE-5'-DIPHOSPHATE

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12 December 2020

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12 December 2020

Assembly of pure tubulin in the absence of free GTP: effect of magnesium, glycerol, ATP, and the nonhydrolyzable GTP analogues

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12 December 2020

Microtubule assembly in living cells after release from nocodazole block: the effects of metabolic inhibitors, taxol and PH

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12 December 2020

Guanasone 5'-(alpha,beta-methylene)triphosphate enhances specifically microtubule nucleation and stops the treadmill of tubulin protomers

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12 December 2020

Role of nucleotide hydrolysis in microtubule assembly

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12 December 2020

Identifiers

DOI

10.1091/MBC.3.10.1155

1 reference

31 July 2017

1 reference

31 July 2017

1 reference