Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA. (Q34280883)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA (English)

1 reference

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9 November 2019

1 reference

0 references

2

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9 November 2019

author name string

Michelle A Booden

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Channing J Der

series ordinal

3

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9 November 2019

language of work or name

English

0 references

publication date

1 June 2002

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json

Molecular and Cellular Biology

9 November 2019

published in

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9 November 2019

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

12

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9 November 2019

page(s)

4053-4061

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json

Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEF

9 November 2019

cites work

1 reference

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Constitutive activation of NF-kappa B and secretion of interleukin-8 induced by the G protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus involve G alpha(13) and RhoA.

6 July 2018

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RETRACTED: Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A.

6 July 2018

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Leukemia-associated Rho guanine nucleotide exchange factor, a Dbl family protein found mutated in leukemia, causes transformation by activation of RhoA

6 July 2018

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The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways

6 July 2018

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RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?

6 July 2018

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Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins

6 July 2018

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Leukemia-associated Rho guanine nucleotide exchange factor (LARG) links heterotrimeric G proteins of the G(12) family to Rho

6 July 2018

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Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement.

6 July 2018

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Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins

6 July 2018

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GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins

6 July 2018

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G2A is an oncogenic G protein-coupled receptor

6 July 2018

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Acylation of Galpha(13) is important for its interaction with thrombin receptor, transforming activity and actin stress fiber formation.

6 July 2018

1 reference

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Rho GTPases and their effector proteins

6 July 2018

1 reference

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Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukemia

6 July 2018

1 reference

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Rho-specific binding and guanine nucleotide exchange catalysis by KIAA0380, a dbl family member

6 July 2018

1 reference

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Whither goest the RGS proteins?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Rho as a mediator of G protein-coupled receptor signaling.

6 July 2018

1 reference

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A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein alpha subunit Galpha13

6 July 2018

1 reference

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Specific involvement of G proteins in regulation of serum response factor-mediated gene transcription by different receptors

6 July 2018

1 reference

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Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Mas oncogene signaling and transformation require the small GTP-binding protein Rac

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Rho GTPases and the actin cytoskeleton

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

RGS2/G0S8 is a selective inhibitor of Gqalpha function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Signaling mechanistics: aluminum fluoride for molecule of the year

6 July 2018

1 reference

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Increasing complexity of Ras signal transduction: involvement of Rho family proteins

6 July 2018

1 reference

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Rho GTPases and signaling networks

6 July 2018

1 reference

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The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.

6 July 2018

1 reference

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Structure of RGS4 bound to AlF4--activated G(i alpha1): stabilization of the transition state for GTP hydrolysis

6 July 2018

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6 July 2018

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Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

6 July 2018

1 reference

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Lfc and Lsc oncoproteins represent two new guanine nucleotide exchange factors for the Rho GTP-binding protein

6 July 2018

1 reference

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Identification of a novel guanine nucleotide exchange factor for the Rho GTPase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Heterotrimeric G proteins.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

The Dbl family of oncogenes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Biological assays for Ras transformation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

A series of mammalian expression vectors and characterisation of their expression of a reporter gene in stably and transiently transfected cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Muscarinic acetylcholine receptor subtypes as agonist-dependent oncogenes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Mechanisms for reversible regulation between G13 and Rho exchange factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Constitutively active Galphaq and Galpha13 trigger apoptosis through different pathways

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

Cell cycle-dependent activation of Ras.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=133844

The GTPase-activating protein RGS4 stabilizes the transition state for nucleotide hydrolysis

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12024019

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.22.12.4053-4061.2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12024019%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

12024019

1 reference