Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype (Q34304761)

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English	Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype (English)

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Europe PubMed Central

PubMed publication ID

1 August 2017

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based on heuristic

inferred from title

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based on heuristic

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author name string

David J Mancuso

1

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1 August 2017

Harold F Sims

2

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1 August 2017

Xianlin Han

3

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Europe PubMed Central

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1 August 2017

Christopher M Jenkins

4

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1 August 2017

Shao Ping Guan

5

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Europe PubMed Central

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1 August 2017

Kui Yang

6

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Europe PubMed Central

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1 August 2017

Sung Ho Moon

7

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Europe PubMed Central

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1 August 2017

Terri Pietka

8

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Europe PubMed Central

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1 August 2017

Nada A Abumrad

9

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1 August 2017

Paul H Schlesinger

10

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1 August 2017

Richard W Gross

11

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1 August 2017

language of work or name

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publication date

8 October 2007

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1 August 2017

Journal of Biological Chemistry

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1 August 2017

282

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PubMed publication ID

1 August 2017

48

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Europe PubMed Central

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1 August 2017

34611-34622

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

Functional diagnostics in mitochondrial diseases

1 reference

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6 July 2018

Alterations in myocardial cardiolipin content and composition occur at the very earliest stages of diabetes: a shotgun lipidomics study

1 reference

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Mitochondrial diseases: a nosological update.

1 reference

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PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis

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Structures and physiological roles of 13 integral lipids of bovine heart cytochrome c oxidase

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Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis

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Mitochondrial disease--its impact, etiology, and pathology.

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Regulation of Triglyceride Metabolism. II. Function of mitochondrial GPAT1 in the regulation of triacylglycerol biosynthesis and insulin action

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Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance

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The enzymatic function of tafazzin

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Barth syndrome, a human disorder of cardiolipin metabolism

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Mitochondria: more than just a powerhouse

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Cardiac and clinical phenotype in Barth syndrome

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Characterization of the human patatin-like phospholipase family

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A new look at UCP 1.

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Calcium-independent phospholipase A2 localizes in and protects mitochondria during apoptotic induction by staurosporine

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Mitochondrial Ca2+ transport, permeability transition and oxidative stress in cell death: implications in cardiotoxicity, neurodegeneration and dyslipidemias

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Mechanisms of cytochrome c release from mitochondria

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Thermogenic mechanisms and their hormonal regulation

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Shotgun lipidomics of cardiolipin molecular species in lipid extracts of biological samples

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A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

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Thermoregulation: what role for UCPs in mammals and birds?

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Medium-chain acyl-CoA dehydrogenase deficiency in gene-targeted mice

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Hormonal regulation of mitochondrial energy production.

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Shotgun lipidomics: multidimensional MS analysis of cellular lipidomes

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Respiration uncoupling and metabolism in the control of energy expenditure

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Mitochondrial energy metabolism in heart failure: a question of balance

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PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

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Carnitine in type 2 diabetes

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6 July 2018

Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion

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Group VIA phospholipase A2 forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIbeta expressed in pancreatic islet beta-cells

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The expression and function of a group VIA calcium-independent phospholipase A2 (iPLA2beta) in beta-cells

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Mitochondrial signaling pathways: a receiver/integrator organelle

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Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples

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Male mice that do not express group VIA phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility.

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Heart mitochondria signaling pathways: appraisal of an emerging field

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Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta

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The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process

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Lysophosphatidic acid, LPA: a bad boy becomes good

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Cold-induced recruitment of brown adipose tissue thermogenesis.

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Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis

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Pleiotropic effects of fatty acids on pancreatic beta-cells

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Gluing the respiratory chain together. Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane

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Deficiency of tetralinoleoyl-cardiolipin in Barth syndrome

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Enzymatic properties of human cytosolic phospholipase A(2)gamma

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Inhibition of mitochondrial calcium-independent phospholipase A2 (iPLA2) attenuates mitochondrial phospholipid loss and is cardioprotective

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Life without UCP1: mitochondrial, cellular and organismal characteristics of the UCP1-ablated mice.

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Mitochondrial defects in neurodegenerative disease

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Defective remodeling of cardiolipin and phosphatidylglycerol in Barth syndrome

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Diabetes-induced changes in specific lipid molecular species in rat myocardium

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Remodeling of cardiolipin by phospholipid transacylation.

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Polymorphic Phase Behavior of Cardiolipin Derivatives Studied by Coarse-Grained Molecular Dynamics

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Identification of calcium-independent phospholipase A2gamma in mitochondria and its role in mitochondrial oxidative stress

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased mitochondrial proton leak in skeletal muscle mitochondria of UCP1-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17923475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M707795200

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

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