Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation (Q34305376)

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English	Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

1 August 2017

Quercetin and allopurinol ameliorate kidney injury in STZ-treated rats with regulation of renal NLRP3 inflammasome activation and lipid accumulation (English)

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

inflammasome complex

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Chuang Wang

1

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Europe PubMed Central

PubMed publication ID

1 August 2017

Ying Pan

2

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Europe PubMed Central

PubMed publication ID

1 August 2017

Qing-Yu Zhang

3

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Europe PubMed Central

PubMed publication ID

1 August 2017

Fu-Meng Wang

4

1 reference

Europe PubMed Central

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1 August 2017

Ling-Dong Kong

5

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Europe PubMed Central

PubMed publication ID

1 August 2017

language of work or name

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publication date

11 June 2012

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Europe PubMed Central

PubMed publication ID

1 August 2017

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Europe PubMed Central

PubMed publication ID

1 August 2017

7

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Europe PubMed Central

PubMed publication ID

1 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

e38285

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

copyright license

Creative Commons Attribution 4.0 International

11 June 2012

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April 2022 Public Data File from Crossref

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Inflammasome is a central player in the induction of obesity and insulin resistance

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Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy.

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Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice.

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Type 2 diabetes as an inflammatory disease

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The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

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6 July 2018

Serum uric acid as a new player in the development of diabetic nephropathy

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6 July 2018

Lipotoxicity in diabetic nephropathy: the potential role of fatty acid oxidation

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An inflammasome-independent role for epithelial-expressed Nlrp3 in renal ischemia-reperfusion injury

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6 July 2018

Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-{alpha}-mediated inflammation and insulin resistance in primary human adipocytes.

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Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

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The NLRP3 inflammasome promotes renal inflammation and contributes to CKD.

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Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation

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Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis

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Role of IL-1beta in type 2 diabetes

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6 July 2018

PPARalpha: an emerging therapeutic target in diabetic microvascular damage.

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NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

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6 July 2018

Expression of apolipoprotein B in the kidney attenuates renal lipid accumulation

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The role of potassium in inflammasome activation by bacteria

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Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

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Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

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Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism

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6 July 2018

Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid

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6 July 2018

Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice

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6 July 2018

Serum uric acid as a predictor for development of diabetic nephropathy in type 1 diabetes: an inception cohort study

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6 July 2018

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

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Fatty acid metabolism: target for metabolic syndrome.

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6 July 2018

Inflammation is associated with a decrease of lipogenic factors in omental fat in women

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Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

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The role of inflammatory cytokines in diabetic nephropathy.

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6 July 2018

Quercetin reduces blood pressure in hypertensive subjects

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6 July 2018

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6 July 2018

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6 July 2018

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Renal tubular triglyercide accumulation following endotoxic, toxic, and ischemic injury.

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Fatty acid import into mitochondria

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Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis

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Allopurinol, rutin, and quercetin attenuate hyperuricemia and renal dysfunction in rats induced by fructose intake: renal organic ion transporter involvement.

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Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese Zucker rats

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Quercetin, an anti-oxidant bioflavonoid, attenuates diabetic nephropathy in rats

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Erythromycin ameliorates renal injury via anti-inflammatory effects in experimental diabetic rats

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Protective effect of quercetin against gentamicin-induced nephrotoxicity in rats.

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Quercetin allievates oxidative stress in streptozotocin-induced diabetic rats

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Effects of allopurinol, a xanthine oxidase inhibitor, on renal injury in hypercholesterolemia-induced hypertensive rats

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Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes

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Glucose directly links to lipid metabolism through high affinity interaction with peroxisome proliferator-activated receptor alpha

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Short term effects of L-carnitine on serum lipids in STZ-induced diabetic rats

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Carnitine as a preventive agent in experimental renal ischemia-reperfusion injury

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Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus.

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Effect of allopurinol in decreasing proteinuria in type 2 diabetic patients

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28 October 2018

Relations of serum interleukin 18 levels to serum lipid and glucose concentrations in an apparently healthy adult population

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28 October 2018

Thiazide diuretics exacerbate fructose-induced metabolic syndrome

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https://pubmed.ncbi.nlm.nih.gov/22701621

12 December 2020

based on heuristic

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Elevated levels of interleukin-18 and tumor necrosis factor-alpha in serum of patients with type 2 diabetes mellitus: relationship with diabetic nephropathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701621

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperuricemia-hyperlipemia association in the absence of obesity and alcohol abuse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701621

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extent and persistence of streptozotocin-induced DNA damage and cell proliferation in rat kidney as determined by in vivo alkaline elution and BrdUrd labeling assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/22701621

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0038285

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

2012PLoSO...738285W

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

1 August 2017

ResearchGate publication ID

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