Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111. (Q34300762)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22994368%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK-21273 in comparison with SB-612111 (English)

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13 February 2020

0 references

1

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13 February 2020

Mattia Volta

4

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13 February 2020

Davide Malfacini

5

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13 February 2020

author name string

F Mela

2

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13 February 2020

M Budri

3

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13 February 2020

S Molinari

6

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N T Zaveri

7

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13 February 2020

S Ronzoni

8

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P Petrillo

9

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13 February 2020

G Calò

10

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M Morari

11

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language of work or name

English

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publication date

1 February 2013

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British Journal of Pharmacology

13 February 2020

published in

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volume

168

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issue

4

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page(s)

863-879

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Further evidence for an involvement of nociceptin/orphanin FQ in the pathophysiology of Parkinson’s disease: a behavioral and neurochemical study in reserpinized mice

13 February 2020

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MPTP treatment increases expression of pre-pro-nociceptin/orphanin FQ mRNA in a subset of substantia nigra reticulata neurons

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The nociceptin/orphanin FQ (NOP) receptor antagonist J-113397 enhances the effects of levodopa in the MPTP-lesioned nonhuman primate model of Parkinson's disease

6 July 2018

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Nociceptin/orphanin FQ receptor blockade attenuates MPTP-induced parkinsonism.

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Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: in vivo studies.

6 July 2018

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Evidence in locomotion test for the functional heterogeneity of ORL-1 receptors

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Modification of Nociception and Morphine Tolerance by the Selective Opiate Receptor-Like Orphan Receptor Antagonist (–)-cis-1-Methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol (SB-612111)

6 July 2018

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Nociceptin/orphanin FQ and opioid receptor-like receptor mRNA expression in dopamine systems

6 July 2018

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The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family

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6 July 2018

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An automated rotarod method for quantitative drug-free evaluation of overall motor deficits in rat models of parkinsonism

6 July 2018

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Address and message sequences for the nociceptin receptor: a structure-activity study of nociceptin-(1-13)-peptide amide.

6 July 2018

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The mouse vas deferens: a pharmacological preparation sensitive to nociceptin

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6 July 2018

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Pharmacological profile of NOP receptors coupled with calcium signaling via the chimeric protein G alpha qi5.

21 January 2018

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Ro 64-6198 [(1S,3aS)-8-(2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one] acts differently from nociceptin/orphanin FQ in rat periaqueductal gray slices

21 January 2018

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Endogenous nociceptin/orphanin FQ (N/OFQ) contributes to haloperidol-induced changes of nigral amino acid transmission and parkinsonism: a combined microdialysis and behavioral study in naïve and nociceptin/orphanin FQ receptor knockout mice.

21 January 2018

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Striatal dopamine-NMDA receptor interactions in the modulation of glutamate release in the substantia nigra pars reticulata in vivo: opposite role for D1 and D2 receptors

21 January 2018

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Blockade of nociceptin/orphanin FQ transmission in rat substantia nigra reverses haloperidol-induced akinesia and normalizes nigral glutamate release

21 January 2018

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Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease.

21 January 2018

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The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway.

21 January 2018

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The novel nociceptin/orphanin FQ receptor antagonist Trap-101 alleviates experimental parkinsonism through inhibition of the nigro-thalamic pathway: positive interaction with L-DOPA.

21 January 2018

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Brain interstitial nociceptin/orphanin FQ levels are elevated in Parkinson's disease

21 January 2018

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Short-term effects of the nociceptin receptor antagonist Compound B on the development of methamphetamine sensitization in mice: a behavioral and c-fos expression mapping study

21 January 2018

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Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

21 January 2018

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Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: in vitro studies.

21 January 2018

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Identification of an achiral analogue of J-113397 as potent nociceptin/orphanin FQ receptor antagonist.

21 January 2018

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Dual motor response to l-dopa and nociceptin/orphanin FQ receptor antagonists in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) treated mice: Paradoxical inhibition is relieved by D(2)/D(3) receptor blockade

21 January 2018

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21 January 2018

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Chronic treatment with the selective NOP receptor antagonist [Nphe 1, Arg 14, Lys 15]N/OFQ-NH 2 (UFP-101) reverses the behavioural and biochemical effects of unpredictable chronic mild stress in rats

21 January 2018

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Pharmacological profile and antiparkinsonian properties of the novel nociceptin/orphanin FQ receptor antagonist 1-[1-cyclooctylmethyl-5-(1-hydroxy-1-methyl-ethyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-3-ethyl-1,3-dihydro-benzoimidazol-2-one (GF-4).

21 January 2018

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Further studies on the pharmacological features of the nociceptin/orphanin FQ receptor ligand ZP120

21 January 2018

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Dopamine–nociceptin/orphanin FQ interactions in the substantia nigra reticulata of hemiparkinsonian rats: Involvement of D2/D3 receptors and impact on nigro-thalamic neurons and motor activity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22994368

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1476-5381.2012.02219.X

1 reference

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13 February 2020

1 reference

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13 February 2020

PubMed publication ID

22994368

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22994368%20AND%20SRC:MED&resulttype=core&format=json