The future of human gene therapy (Q34317814)

1 August 2017

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title

The future of human gene therapy (English)

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1 August 2017

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Rubanyi GM

1

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1 August 2017

publication date

1 June 2001

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Molecular Aspects of Medicine

1 August 2017

published in

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1 August 2017

volume

22

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1 August 2017

issue

3

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1 August 2017

page(s)

113-142

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Lentiviral vectors--the promise of gene therapy within reach?

1 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

The delivery of angiogenic factors to the heart by microsphere therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Stem cell therapy and gene transfer for regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Inhibition of intimal hyperplasia after vein grafting by in vivo transfer of human senescent cell-derived inhibitor-1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Angiogenic-induced enhancement of collateral blood flow to ischemic myocardium by vascular endothelial growth factor in dogs

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Dendritic cells and the control of immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Constitutive expression of phVEGF165 after intramuscular gene transfer promotes collateral vessel development in patients with critical limb ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Reports of adenovector "death" are greatly exaggerated

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene therapy as drug development

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Adenovirus-mediated over-expression of the cyclin/cyclin-dependent kinase inhibitor, p21 inhibits vascular smooth muscle cell proliferation and neointima formation in the rat carotid artery model of balloon angioplasty

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Cytostatic gene therapy for vascular proliferative disorders with a constitutively active form of the retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Modulation of the inflammatory properties and hepatotoxicity of recombinant adenovirus vectors by the viral E4 gene products.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Controlling mammalian gene expression with small molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Regulated gene expression systems

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene therapy for restenosis: are we ready?

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Targeted gene delivery by tropism-modified adenoviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Progress and potential for gene-based medicines

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Molecular therapies for vascular diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Intracoronary gene transfer of fibroblast growth factor-5 increases blood flow and contractile function in an ischemic region of the heart

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Dimeric ligands define a role for transcriptional activation domains in reinitiation

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Researchers and regulators reflect on first gene therapy death

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Human gene marker/therapy clinical protocols

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Inhibition of cellular ras prevents smooth muscle cell proliferation after vascular injury in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Development of a novel fusogenic viral liposome system (HVJ-liposomes) and its applications to the treatment of acquired diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Genetic targeting of adenoviral vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: results of a phase I randomized, double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Catheter-mediated vascular endothelial growth factor gene transfer to human coronary arteries after angioplasty

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Ultrasound enhances reporter gene expression after transfection of vascular cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Reversed-phase high-performance liquid chromatographic assay for the adenovirus type 5 proteome.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Virus treatment questioned after gene therapy death

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Nonviral gene therapy: promises and challenges

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Systemic gene delivery expands the repertoire of effective antiangiogenic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Pharmacologic control of a humanized gene therapy system implanted into nude mice

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: the PREVENT single-centre, randomised, controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene therapy for cancer--managing expectations

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

High-efficiency gene transfer into skeletal muscle mediated by electric pulses

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

AAV vectors: is clinical success on the horizon?

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

A gene therapy strategy using a transcription factor decoy of the E2F binding site inhibits smooth muscle proliferation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

In vivo transfection of cis element "decoy" against nuclear factor-kappaB binding site prevents myocardial infarction

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Nitric oxide synthase modulates angiogenesis in response to tissue ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Complex models for the study of gene function in cardiovascular biology

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Vascular endothelial growth factor (VEGF) and its receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Adenovirus-mediated gene transfer into normal rabbit arteries results in prolonged vascular cell activation, inflammation, and neointimal hyperplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene therapy for vascular smooth muscle cell proliferation after arterial injury

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Specific tumor-cell killing with adenovirus vectors containing the apoptin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Immunotherapy of malignancy by in vivo gene transfer into tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Inhibition of neointimal cell bcl-x expression induces apoptosis and regression of vascular disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

A humanized system for pharmacologic control of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene therapy for restenosis: getting nearer the heart of the matter

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Induction of neoangiogenesis in ischemic myocardium by human growth factors: first clinical results of a new treatment of coronary heart disease

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Therapeutic angiogenesis with basic fibroblast growth factor: technique and early results

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Development of a hypoxia-responsive vector for tumor-specific gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Direct intramuscular injection of plasmid DNA encoding angiopoietin-1 but not angiopoietin-2 augments revascularization in the rabbit ischemic hindlimb

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Antisense c-myb oligonucleotides inhibit intimal arterial smooth muscle cell accumulation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

VEGF gene delivery to muscle: potential role for vasculogenesis in adults

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

A new cationic liposome DNA complex enhances the efficiency of arterial gene transfer in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Efficient and stable transduction of cardiomyocytes after intramyocardial injection or intracoronary perfusion with recombinant adeno-associated virus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene therapy with vascular endothelial growth factor for inoperable coronary artery disease

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Enhanced inhibition of hepatitis B virus production by asialoglycoprotein receptor-directed interferon

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Targeting angiogenesis: genetic intervention which strikes at the weak link of tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Expression of cyclin-dependent kinase inhibitors in vascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Glucose regulated production of human insulin in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Direct intramuscular gene transfer of naked DNA encoding vascular endothelial growth factor augments collateral development and tissue perfusion

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Efficient adventitial gene delivery to rabbit carotid artery with cationic polymer-plasmid complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Vascular endothelial growth factor/vascular permeability factor augments nitric oxide release from quiescent rabbit and human vascular endothelium.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Physiologically responsive gene therapy

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https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene therapy -- promises, problems and prospects

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https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Strategies for achieving multiple layers of selectivity in gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Microbubbles targeted to intercellular adhesion molecule-1 bind to activated coronary artery endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

A regulatory system for use in gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

The human genome project: past, present, and future

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A2 in endothelial cells via p42/p44 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

1 reference

7 January 2021

Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Adenovirus targeted to heparan-containing receptors increases its gene delivery efficiency to multiple cell types

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Increased in vitro and in vivo gene transfer by adenovirus vectors containing chimeric fiber proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Adenoviruses as gene-delivery vehicles

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Effects of epidermal growth factor, transferrin, and insulin on lipofection efficiency in human lung carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Gene gun and other non-viral approaches for cancer gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Angiotensin-converting enzyme inhibition increases collateral-dependent muscle blood flow.

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Role of the p21 cyclin-dependent kinase inhibitor in limiting intimal cell proliferation in response to arterial injury

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Vascular gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Cardiovascular gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Transfer of wild-type p53 gene effectively inhibits vascular smooth muscle cell proliferation in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

Roles of adeno-associated virus Rep protein and human chromosome 19 in site-specific recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0098-2997%2801%2900004-8

7 January 2021

10.1016/S0098-2997(01)00004-8

Identifiers

DOI

1 reference

release_5s3lkoerenaz3cmk2qrpv4y454

1 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5s3lkoerenaz3cmk2qrpv4y454

24 November 2022

mapped directly with Wikidata item

1 reference