Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan (Q34312222)

1 August 2017

title

Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan (English)

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1 August 2017

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Ugur Ozerdem

1

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1 August 2017

William B Stallcup

series ordinal

2

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1 August 2017

publication date

1 January 2004

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1 August 2017

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1 August 2017

volume

7

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1 August 2017

issue

3

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1 August 2017

page(s)

269-276

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Adult bone marrow-derived cells recruited during angiogenesis comprise precursors for periendothelial vascular mural cells

1 August 2017

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Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

6 July 2018

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6 July 2018

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The glial precursor proteoglycan, NG2, is expressed on tumour neovasculature by vascular pericytes in human malignant brain tumours.

6 July 2018

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NG2 proteoglycan mediates beta1 integrin-independent cell adhesion and spreading on collagen VI.

6 July 2018

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Endothelium-specific platelet-derived growth factor-B ablation mimics diabetic retinopathy

6 July 2018

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Analysis of mural cell recruitment to tumor vessels

6 July 2018

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NG2 proteoglycan is expressed exclusively by mural cells during vascular morphogenesis

6 July 2018

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Time course of endothelial cell proliferation and microvascular remodeling in chronic inflammation

6 July 2018

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Pericytes: cell biology and pathology

6 July 2018

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Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis

6 July 2018

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Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood

6 July 2018

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Diversity within pericytes

6 July 2018

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Retinal and choroidal neovascularization

6 July 2018

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Cytoskeletal reorganization induced by engagement of the NG2 proteoglycan leads to cell spreading and migration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Angiogenesis in the bovine corpus luteum: an immunocytochemical and ultrastructural study

6 July 2018

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High-affinity binding of basic fibroblast growth factor and platelet-derived growth factor-AA to the core protein of the NG2 proteoglycan

6 July 2018

1 reference

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PDGF (alpha)-receptor is unresponsive to PDGF-AA in aortic smooth muscle cells from the NG2 knockout mouse

6 July 2018

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Blood vessel maturation: vascular development comes of age

6 July 2018

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Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

A central segment of the NG2 proteoglycan is critical for the ability of glioma cells to bind and migrate toward type VI collagen

6 July 2018

1 reference

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Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

6 July 2018

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Vascular development: cellular and molecular regulation.

6 July 2018

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Mechanisms of angiogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Blood vessel formation: what is its molecular basis?

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Aminopeptidase a is a constituent of activated pericytes in angiogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

6 July 2018

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Angiogenesis in cancer, vascular, rheumatoid and other disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Flow cytometric measurement of total DNA content and incorporated bromodeoxyuridine

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Altering the genome by homologous recombination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Recent advances in pericyte biology--implications for health and disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Expression of the high molecular weight melanoma-associated antigen by pericytes during angiogenesis in tumors and in healing wounds.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

NG2 proteoglycan expression by pericytes in pathological microvasculature.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Chondroitin sulfate and cytoplasmic domain-dependent membrane targeting of the NG2 proteoglycan promotes retraction fiber formation and cell polarization.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Binding of the NG2 proteoglycan to kringle domains modulates the functional properties of angiostatin and plasmin(ogen).

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Vasculogenesis in the day 6.5 to 9.5 mouse embryo.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Microvascular pericytes express platelet-derived growth factor-beta receptors in human healing wounds and colorectal adenocarcinoma.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Early and extensive contribution of pericytes/vascular smooth muscle cells to microvascular proliferation in glioblastoma multiforme: an immuno-light and immuno-electron microscopic study.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Participation of the NG2 Proteoglycan in Rat Aortic Smooth Muscle Cell Responses to Platelet-Derived Growth Factor

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Cell-cycle analysis using a monoclonal antibody to BrdUrd.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1350818

Engagement of the NG2 proteoglycan triggers cell spreading via rac and p130cas

28 October 2018

1 reference

12 December 2020

Pericyte involvement in capillary sprouting during angiogenesis in situ

1 reference

12 December 2020

Oxygen-induced retinopathy in the mouse

1 reference

12 December 2020

A model of angiogenesis in the mouse cornea

1 reference

12 December 2020

Capillaropathy and capillaroneogenesis in the pathogenesis of rosacea

1 reference

12 December 2020

Endothelial Cells Modulate the Proliferation of Mural Cell Precursors via Platelet-Derived Growth Factor-BB and Heterotypic Cell Contact

1 reference

12 December 2020

Evidence for a role of capillary pericytes in vascular growth of the developing ovine corpus luteum

1 reference

12 December 2020

10.1007/S10456-004-4182-6

Identifiers

DOI

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1 August 2017

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1 August 2017

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