Alzheimer's disease and Abeta toxicity: from top to bottom (Q34325378)

1 August 2017

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title

Alzheimer's disease and Abeta toxicity: from top to bottom (English)

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1 August 2017

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Small DH

1

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1 August 2017

Mok SS

series ordinal

2

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1 August 2017

Bornstein JC

series ordinal

3

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1 August 2017

language of work or name

English

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publication date

1 August 2001

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Nature Reviews Neuroscience

1 August 2017

published in

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1 August 2017

volume

2

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1 August 2017

issue

8

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1 August 2017

page(s)

595-598

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Alzheimer's disease and the amyloid beta protein: What is the role of amyloid?

1 August 2017

cites work

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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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Cell death or synaptic loss in Alzheimer disease

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Neural networks and physical systems with emergent collective computational abilities

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Neurons with graded response have collective computational properties like those of two-state neurons

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How do cell assemblies encode information in the brain?

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Associative memory neural network with low temporal spiking rates

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A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease.

21 January 2018

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A quantitative study of the neurofibrillary tangles and the choline acetyltransferase activity in the cerebral cortex and the amygdala in Alzheimer's disease

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A neural model of memory impairment in diffuse cerebral atrophy.

21 January 2018

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Synaptic plasticity: taming the beast

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Homeostatic plasticity in neuronal networks: the more things change, the more they stay the same

21 January 2018

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Hebb and homeostasis in neuronal plasticity

21 January 2018

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Effective neuronal learning with ineffective Hebbian learning rules.

21 January 2018

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Memory maintenance via neuronal regulation.

21 January 2018

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Mechanism for a sliding synaptic modification threshold

21 January 2018

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Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity

21 January 2018

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Requirement of ERK activation for visual cortical plasticity

21 January 2018

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Regulation of synaptic efficacy by coincidence of postsynaptic APs and EPSPs

21 January 2018

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A synaptically controlled, associative signal for Hebbian plasticity in hippocampal neurons.

21 January 2018

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Modeling synaptic plasticity in conjuction with the timing of pre- and postsynaptic action potentials

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Plaque-induced neurite abnormalities: implications for disruption of neural networks in Alzheimer's disease

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Imaging of calcium variations in living dendritic spines of cultured rat hippocampal neurons

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Alzheimer's disease as a disorder of mechanisms underlying structural brain self-organization

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Calcium-dependent alterations in dendritic architecture of hippocampal pyramidal neurons

21 January 2018

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Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

21 January 2018

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beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology

21 January 2018

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alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity

21 January 2018

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Hydrogen peroxide mediates amyloid beta protein toxicity

21 January 2018

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Amyloid peptides are toxic via a common oxidative mechanism

21 January 2018

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A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

21 January 2018

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Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione.

21 January 2018

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Molecular mechanism of neurodegeneration induced by Alzheimer's beta-amyloid protein: channel formation and disruption of calcium homeostasis

21 January 2018

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Alzheimer's beta-amyloid, human islet amylin, and prion protein fragment evoke intracellular free calcium elevations by a common mechanism in a hypothalamic GnRH neuronal cell line

21 January 2018

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Neurotoxicity induces cleavage of p35 to p25 by calpain

21 January 2018

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Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease.

21 January 2018

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Inhibition of the electrostatic interaction between β-amyloid peptide and membranes prevents β-amyloid-induced toxicity

21 January 2018

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Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease.

21 January 2018

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Inhibitors of V-type ATPases, bafilomycin A1 and concanamycin A, protect against beta-amyloid-mediated effects on 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction

21 January 2018

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Multiple pathways of apoptosis in PC12 cells. CrmA inhibits apoptosis induced by beta-amyloid

21 January 2018

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Neuronal apoptosis induced by beta-amyloid is mediated by caspase-8.

21 January 2018

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

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c-Jun contributes to amyloid beta-induced neuronal apoptosis but is not necessary for amyloid beta-induced c-jun induction.

21 January 2018

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beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation

21 January 2018

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Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death

21 January 2018

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E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3.

21 January 2018

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Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

21 January 2018

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RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

21 January 2018

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Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease

21 January 2018

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Activation of microglial cells by beta-amyloid protein and interferon-gamma.

21 January 2018

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Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

21 January 2018

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Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor

21 January 2018

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Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism

21 January 2018

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Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signalin

21 January 2018

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An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease

21 January 2018

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Involvement of auditory cortical and hippocampal neurons in auditory working memory and reference memory in the rat.

21 January 2018

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7 January 2021

Neuronal regulation versus synaptic unlearning in memory maintenance mechanisms

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7 January 2021

Distribution of a kainate/AMPA receptor mRNA in normal and Alzheimer brain.

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7 January 2021

Stable Hebbian learning from spike timing-dependent plasticity.

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7 January 2021

Dendritic spikes are enhanced by cooperative network activity in the intact hippocampus.

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7 January 2021

Nerve terminal remodeling visualized in living mice by repeated examination of the same neuron

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7 January 2021

L-Type calcium channels are required for one form of hippocampal mossy fiber LTP

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7 January 2021

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

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7 January 2021

Ca2+ channel blockers attenuate beta-amyloid peptide toxicity to cortical neurons in culture.

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7 January 2021

The amyloid beta-protein of Alzheimer's disease increases acetylcholinesterase expression by increasing intracellular calcium in embryonal carcinoma P19 cells.

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7 January 2021

Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease

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7 January 2021

beta -Amyloid peptide blocks the response of alpha 7-containing nicotinic receptors on hippocampal neurons

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7 January 2021

Astrocytes from cerebral cortex or striatum attract adult host serotoninergic axons into intrastriatal ventral mesencephalic co-grafts.

1 reference

7 January 2021

An Amyloid Peptide, βA4 25–35, Mimics the Function of Substance P on Modulation of Nicotine‐Evoked Secretion and Desensitization in Cultured Bovine Adrenal Chromaffin Cells

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7 January 2021

Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death

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7 January 2021

Amyloid beta-mediated oxidative and metabolic stress in rat cortical neurons: no direct evidence for a role for H2O2 generation

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7 January 2021

Caspase-2 mediates neuronal cell death induced by beta-amyloid

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7 January 2021

Differential induction of immediate early gene proteins in cultured neurons by beta-amyloid (A beta): association of c-Jun with A beta-induced apoptosis.

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7 January 2021

Aggregated amyloid-beta protein induces cortical neuronal apoptosis and concomitant "apoptotic" pattern of gene induction.

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7 January 2021

beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis.

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7 January 2021

beta-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes.

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7 January 2021

Identifiers

DOI

10.1038/35086072

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Dimensions Publication ID

1 August 2017

1000563080

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