Isolation of high affinity human antibodies directly from large synthetic repertoires. (Q34331136)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8045255%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

title

Isolation of high affinity human antibodies directly from large synthetic repertoires (English)

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23 October 2019

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Griffiths AD

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23 October 2019

Williams SC

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23 October 2019

Hartley O

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23 October 2019

Tomlinson IM

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Waterhouse P

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23 October 2019

Crosby WL

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Kontermann RE

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23 October 2019

Jones PT

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23 October 2019

Low NM

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23 October 2019

Allison TJ

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23 October 2019

language of work or name

English

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publication date

1 July 1994

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23 October 2019

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23 October 2019

volume

13

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23 October 2019

issue

14

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23 October 2019

page(s)

3245-3260

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Segregation of New Lysogenic Types during Growth of a Doubly Lysogenic Strain Derived from Escherichia Coli K12.

23 October 2019

cites work

1 reference

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Combinatorial infection and in vivo recombination: a strategy for making large phage antibody repertoires

6 July 2018

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Length distribution of CDRH3 in antibodies

6 July 2018

1 reference

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Tolerance and ways to break it.

6 July 2018

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"Diabodies": small bivalent and bispecific antibody fragments

6 July 2018

1 reference

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Selection of human anti-hapten antibodies from semisynthetic libraries

6 July 2018

1 reference

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A directory of human germ-line V kappa segments reveals a strong bias in their usage

6 July 2018

1 reference

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Heavy-chain directed B-cell maturation: continuous clonal selection beginning at the pre-B cell stage

6 July 2018

1 reference

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Making antibodies by phage display technology

6 July 2018

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Cloning and sequencing of human immunoglobulin V lambda gene segments

6 July 2018

1 reference

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Human antibody fragments specific for human blood group antigens from a phage display library.

6 July 2018

1 reference

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Human anti-self antibodies with high specificity from phage display libraries

6 July 2018

1 reference

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Antibody fragments from a 'single pot' phage display library as immunochemical reagents

6 July 2018

1 reference

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P1 site-specific recombination: nucleotide sequence of the recombining sites

6 July 2018

1 reference

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Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites

6 July 2018

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

6 July 2018

1 reference

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Formation, induction, and curing of bacteriophage P1 lysogens

6 July 2018

1 reference

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The role of the loxP spacer region in P1 site-specific recombination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Production of single-stranded plasmid DNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

High efficiency transformation of E. coli by high voltage electroporation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Direct clone characterization from plaques and colonies by the polymerase chain reaction.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Conformations of immunoglobulin hypervariable regions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Participation of the lytic replicon in bacteriophage P1 plasmid maintenance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Phage antibodies: filamentous phage displaying antibody variable domains

6 July 2018

1 reference

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Regulated expression of foreign genes fused to lac: control by glucose levels in growth medium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Structure and expression of the human immunoglobulin lambda genes

6 July 2018

1 reference

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Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

A surface expression vector for antibody screening

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Making antibody fragments using phage display libraries

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Kinetic maturation of an immune response

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Assembly of combinatorial antibody libraries on phage surfaces: the gene III site

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

By-passing immunization. Human antibodies from V-gene libraries displayed on phage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

The effect of antibody isotype and antigenic epitope density on the complement-fixing activity of immune complexes: a systematic study using chimaeric anti-NIP antibodies with human Fc regions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Analysis of macromolecular interactions using immobilized ligands.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Selection of phage antibodies by binding affinity. Mimicking affinity maturation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Structural repertoire of the human VH segments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Selective enhancement of the tumour necrotic activity of TNF alpha with monoclonal antibody

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Fab assembly and enrichment in a monovalent phage display system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

By-passing immunization: building high affinity human antibodies by chain shuffling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity

6 July 2018

1 reference

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Inheritance of antibody specificity V. Anti-2-phenyloxazolone in the mouse

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Introduction of a fluorescent label into the carbohydrate moiety of glycoconjugates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Theoretical studies of clonal selection: Minimal antibody repertoire size and reliability of self-non-self discrimination

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Human immunoglobulin VH and D segments on chromosomes 15q11.2 and 16p11.2.

6 July 2018

1 reference

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Mechanisms of ligand binding by monoclonal anti-fluorescyl antibodies.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=395221

Immobilization chemistries suitable for use in the BIAcore surface plasmon resonance detector

27 October 2018

1 reference

12 December 2020

Linkage of low and high affinity anti-fluorescein idiotype families

1 reference

12 December 2020

Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system

1 reference

12 December 2020

Definition of the human immunoglobulin variable lambda (IGLV) gene subgroups

1 reference

12 December 2020

Idiotypic cross-reactivity of low-affinity anti-fluorescyl monoclonal antibodies

1 reference

12 December 2020

Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors

1 reference

12 December 2020

Analysis of active antibody concentration. Separation of affinity and concentration parameters

1 reference

12 December 2020

Construction, characterization, and mutagenesis of an anti-fluorescein single chain antibody idiotype family

1 reference

12 December 2020

Partial elucidation of an anti-hapten repertoire in BALB/c mice: Comparative characterization of several monoclonal anti-fluorescyl antibodies

1 reference

12 December 2020

Canonical structures for the hypervariable regions of immunoglobulins

1 reference

12 December 2020

Somatic mutation and the maturation of immune response to 2-phenyl oxazolone

1 reference

12 December 2020

Comparative properties of monoclonal antibodies comprising a high-affinity anti-fluorescyl idiotype family

1 reference

12 December 2020

DETERMINATION OF ANTIBODY AFFINITY FOR HAPTENS AND ANTIGENS BY MEANS OF FLUORESCENCE QUENCHING

1 reference

12 December 2020

Structure of primary anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in normal and idiotypically suppressed C57BL/6 mice

1 reference

12 December 2020

Chemical and serological studies with an iodine-containing synthetic immunological determinant 4-hydroxy-3-iodo-5-nitrophenylacetic acid (NIP) and related compounds

1 reference

12 December 2020

Chemical basis for diversity in antibody specificity analysed by hapten binding to monoclonal anti-4-hydroxy-3-nitrophenacetyl (NP) immunoglobulins

1 reference

12 December 2020

Antibodies biotinylated via sugar moieties

1 reference

12 December 2020

10.1002/J.1460-2075.1994.TB06626.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8045255%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8045255%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

PubMed publication ID

8045255

1 reference