Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers (Q34331346)

1 August 2017

title

Drusen deposits associated with aging and age-related macular degeneration contain nonfibrillar amyloid oligomers (English)

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1 August 2017

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4

Charles G Glabe

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1 August 2017

3

Rakez Kayed

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1 August 2017

5

Ralf Langen

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1 August 2017

Volker Luibl

1

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1 August 2017

Jose M Isas

series ordinal

2

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1 August 2017

Jeannie Chen

series ordinal

6

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1 August 2017

language of work or name

English

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publication date

1 February 2006

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Journal of Clinical Investigation

1 August 2017

published in

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1 August 2017

volume

116

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1 August 2017

issue

2

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1 August 2017

page(s)

378-385

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Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates.

1 August 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

6 July 2018

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6 July 2018

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Drusen in age-related macular degeneration: pathogenesis, natural course, and laser photocoagulation-induced regression

6 July 2018

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6 July 2018

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Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

6 July 2018

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Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

6 July 2018

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6 July 2018

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Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

6 July 2018

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Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes

27 October 2018

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Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers

27 October 2018

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Self-assembly of Abeta(1-42) into globular neurotoxins.

27 October 2018

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Humoral Immune Response to Fibrillar β-Amyloid Peptide

27 October 2018

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Drusen-Associated Degeneration in the Retina

27 October 2018

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Vitronectin is a constituent of ocular drusen and the vitronectin gene is expressed in human retinal pigmented epithelial cells

27 October 2018

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12 December 2020

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

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12 December 2020

Human ocular drusen possess novel core domains with a distinct carbohydrate composition

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12 December 2020

Protofibrillar islet amyloid polypeptide permeabilizes synthetic vesicles by a pore-like mechanism that may be relevant to type II diabetes

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12 December 2020

Immunoreactivity against tau, amyloid precursor protein, and beta-amyloid in the human retina

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12 December 2020

Identifiers

DOI

10.1172/JCI25843

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1 August 2017

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1 August 2017

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