The c-Jun N-terminal protein kinase family of mitogen-activated protein kinases (JNK MAPKs). (Q34365448)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551821%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

review article

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title

The c-Jun N-terminal protein kinase family of mitogen-activated protein kinases (JNK MAPKs) (English)

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11 November 2019

2

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11 November 2019

author name string

R K Barr

series ordinal

1

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11 November 2019

publication date

1 November 2001

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International Journal of Biochemistry & Cell Biology

11 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551821%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

33

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11 November 2019

issue

11

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11 November 2019

page(s)

1047-1063

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Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

11 November 2019

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Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

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c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

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Crystal structure of JNK3: a kinase implicated in neuronal apoptosis

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JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

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Selective interaction of JNK protein kinase isoforms with transcription factors

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Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

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Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

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Cellular Stresses Differentially Activate c-Jun N-terminal Protein Kinases and Extracellular Signal-regulated Protein Kinases in Cultured Ventricular Myocytes

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Stimulation of the stress-activated mitogen-activated protein kinase subfamilies in perfused heart. p38/RK mitogen-activated protein kinases and c-Jun N-terminal kinases are activated by ischemia/reperfusion

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Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

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Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7

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The MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinases

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Identification of a new family of human epithelial protein kinases containing two leucine/isoleucine-zipper domains

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MLK-3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6

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Guanine-nucleotide exchange protein C3G activates JNK1 by a ras-independent mechanism. JNK1 activation inhibited by kinase negative forms of MLK3 and DLK mixed lineage kinases

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

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TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction

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TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase

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Signaling by the germinal center kinase family of protein kinases

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Tumor necrosis factor receptor-associated factor (TRAF) 2 and its role in TNF signaling.

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Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

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Tumor necrosis factor signaling to stress-activated protein kinase (SAPK)/Jun NH2-terminal kinase (JNK) and p38. Germinal center kinase couples TRAF2 to mitogen-activated protein kinase/ERK kinase kinase 1 and SAPK while receptor interacting [...]

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7 January 2021

MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

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Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)

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7 January 2021

TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related

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7 January 2021

Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase

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7 January 2021

Activation of c-Jun-NH2-kinase by UV irradiation is dependent on p21ras

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7 January 2021

Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae

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7 January 2021

MEKK1 binds directly to the c-Jun N-terminal kinases/stress-activated protein kinases

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7 January 2021

A cytoplasmic inhibitor of the JNK signal transduction pathway

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A mammalian scaffold complex that selectively mediates MAP kinase activation

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Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.

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Islet-brain1/JNK-interacting protein-1 is required for early embryogenesis in mice

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c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions

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Transcription factor ATF2 regulation by the JNK signal transduction pathway

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The p38 and ERK MAP kinase pathways cooperate to activate Ternary Complex Factors and c-fos transcription in response to UV light.

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Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

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Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

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7 January 2021

Stress signaling in Drosophila

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7 January 2021

JNK is required for effector T-cell function but not for T-cell activation

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7 January 2021

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

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7 January 2021

SEK1 deficiency reveals mitogen-activated protein kinase cascade crossregulation and leads to abnormal hepatogenesis

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7 January 2021

SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development

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7 January 2021

MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation

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7 January 2021

Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

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7 January 2021

Mekk3 is essential for early embryonic cardiovascular development

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

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7 January 2021

c-Jun and the transcriptional control of neuronal apoptosis

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Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

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7 January 2021

The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival

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Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-alpha in rat mesangial cells.

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Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1.

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Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease

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7 January 2021

The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat

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c-Jun NH2-terminal kinase regulation of the apoptotic response of small cell lung cancer cells to ultraviolet radiation

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Direct inhibition of c-Jun N-terminal kinase in sympathetic neurones prevents c-jun promoter activation and NGF withdrawal-induced death.

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Inhibition of c-Jun N-terminal kinase 1, but not c-Jun N-terminal kinase 2, suppresses apoptosis induced by ischemia/reoxygenation in rat cardiac myocytes

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Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner

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7 January 2021

Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates

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7 January 2021

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

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Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1)

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

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Lack of correlation between activation of Jun-NH2-terminal kinase and induction of apoptosis after detachment of epithelial cells

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7 January 2021

JNK activation is not required for Fas-mediated apoptosis

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7 January 2021

Apoptosis of cerebellar granule cells induced by serum withdrawal, glutamate or beta-amyloid, is independent of Jun kinase or p38 mitogen activated protein kinase activation.

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7 January 2021

Early activation of c-Jun N-terminal kinase and p38 kinase regulate cell survival in response to tumor necrosis factor alpha

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7 January 2021

The Activation of the c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase Signaling Pathways Protects HeLa Cells from Apoptosis Following Photodynamic Therapy with Hypericin

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Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis

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A role for JNK/SAPK in proliferation, but not apoptosis, of IL-3-dependent cells

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Prolactin-induced cell proliferation in PC12 cells depends on JNK but not ERK activation

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The Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells

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7 January 2021

Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons.

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7 January 2021

The JNK and P38 MAP kinase signaling pathways in T cell-mediated immune responses

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7 January 2021

Possible involvement of stress-activated protein kinase signaling pathway and Fas receptor expression in prevention of ischemia/reperfusion-induced cardiomyocyte apoptosis by carvedilol

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7 January 2021

Inhibition of the c-Jun N-terminal kinase (JNK) signaling pathway by curcumin

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7 January 2021

Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages

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Inhibitory effect of curcumin on epidermal growth factor receptor kinase activity in A431 cells

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c-Jun N-terminal kinase mediates apoptotic signaling induced by N-(4-hydroxyphenyl)retinamide.

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7 January 2021

Cep-1347 (KT7515), a semisynthetic inhibitor of the mixed lineage kinase family.

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CEP-1347/KT7515, a JNK pathway inhibitor, supports the in vitro survival of chick embryonic neurons.

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11551821%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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